System for MR image-guided prostate interventions: canine study

Cataloged from PDF version of article.The purpose of this study was to demonstrate the use of a transrectal system that enables precise magnetic resonance (MR) image guidance and monitoring of prostate interventions. The system used a closed-bore 1.5-T MR imaging unit and enables one to take advantage of the higher signal-to-noise ratio achieved with traditional magnet designs, which is crucial for accurate targeting and monitoring of prostate interventions. In the first of the four canine studies, reliable needle placement, with all needles placed within 2 mm of the desired target site, was achieved. In two other studies, MR imaging was used to monitor distribution of injected contrast agent solution (gadopentetate dimeglumine mixed with trypan blue dye) in and around the prostate, thereby confirming that solution had been delivered to the desired tissue and also detecting faulty injections. In the final study, accurate placement and MR imaging of brachytherapy seeds in the prostate were demonstrated. The described system provides a flexible platform for a variety of minimally invasive MR image-guided therapeutic and diagnostic prostate interventions

Increasing uptake of ecosystem service assessments: best practice check-lists for practitioners in Europe

Aiming at understanding the role of plural values in decision-making, the IPBES Values Assessment defined nature valuation broadly as including biophysical, economic and socio-cultural assessments, including ecosystem service assessment. IPBES reviews of scientific literature revealed a lack of documentation of uptake by stakeholders across method types. The EU project SELINA aims to contribute to increasing uptake of ES assessments at different governance levels. This paper reviews guidance in national and local applications by compiling study design recommendations for ES assessments from 111 guidance documents on ES assessments covering 12 European languages. Guidance documents are evaluated for seven diagnostic topics suggested to increase relevance and robustness of ES assessments: ecosystem condition variables; capacity-potential; supply-demand; spatial scaling and resolution capability; social and health benefit compatibility; economic valuation compatibility; and uncertainty assessment. The paper develops the guidance recommendations across these topics into a set of checklists for practitioners and contractors of ES assessments. We find synergies between these study design features and gaps in guidance in relation to the policy cycle. Checklists are aimed at projects self-assessing and improving their design and implementation to increase robustness of their ES assessment. From a knowledge supply perspective, this is expected to increase the likelihood of uptake of results by stakeholders. We end the paper with some cautions on limitations to uptake from different perspectives and the demand for and political uses of ES assessment knowledge

Transrectal prostate biopsy inside closed MRI scanner with remote actuation, under real-time image guidance

Abstract. We present the proof-of-concept prototype of a prostate biopsy robot to be used inside a conventional high-field MRI scanner. A three degree-offreedom (DOF) mechanical device translates and rotates inside the rectum and enters a needle into the body, and steers the needle to a target point pre-selected by the user. The device is guided by real-time images from the scanner. Networked computers process the medical images and enable the clinician to control the motion of the mechanical device that is operated remotely from outside the imager. The system is also applicable to localized prostate therapy and also demonstrates potential in other intra-cavitary procedures

Index terms:

Prostate neoplasms, therapeuti

Postoperative

Abstract We present the concept and prototype of an image-guided robotic system for accurate and consistent placement of percutaneous needles in soft tissue targets under CT-guidance. The system is a promising embodiment of the Surgical CAD/CAM paradigm and as such, easily adaptable to other image guidance modalities, like X-ray fluoroscopy. We also report the first results of pre-clinical experiments on phantoms.