6,178 research outputs found
Creating exotic condensates via quantum-phase-revival dynamics in engineered lattice potentials
In the field of ultracold atoms in optical lattices a plethora of phenomena
governed by the hopping energy and the interaction energy have been
studied in recent years. However, the trapping potential typically present in
these systems sets another energy scale and the effects of the corresponding
time scale on the quantum dynamics have rarely been considered. Here we study
the quantum collapse and revival of a lattice Bose-Einstein condensate (BEC) in
an arbitrary spatial potential, focusing on the special case of harmonic
confinement. Analyzing the time evolution of the single-particle density
matrix, we show that the physics arising at the (temporally) recurrent quantum
phase revivals is essentially captured by an effective single particle theory.
This opens the possibility to prepare exotic non-equilibrium condensate states
with a large degree of freedom by engineering the underlying spatial lattice
potential.Comment: 9 pages, 6 figure
Ionization of clusters in intense laser pulses through collective electron dynamics
The motion of electrons and ions in medium-sized rare gas clusters (1000
atoms) exposed to intense laser pulses is studied microscopically by means of
classical molecular dynamics using a hierarchical tree code. Pulse parameters
for optimum ionization are found to be wavelength dependent. This resonant
behavior is traced back to a collective electron oscillation inside the charged
cluster. It is shown that this dynamics can be well described by a driven and
damped harmonic oscillator allowing for a clear discrimination against other
energy absorption mechanisms.Comment: 4 pages (4 figures
Prediction of gene–phenotype associations in humans, mice, and plants using phenologs
All authors are with the Center for Systems and Synthetic Biology, Institute for Cellular and Molecular Biology, The University of Texas at Austin, Austin, TX 78712, USA. -- Ulf Martin Singh-Blom is with the Program in Computational and Applied Mathematics, The University of Texas at Austin, Austin, TX 78712, USA, and th Unit of Computational Medicine, Department of Medicine, Karolinska Institutet, Stockholm 171 76, Sweden. -- Kriston L. McGary is with the Department of Biological Sciences, Vanderbilt University, Nashville, TN 37235, USA.Background: Phenotypes and diseases may be related to seemingly dissimilar phenotypes in other species by means of the orthology of underlying genes. Such “orthologous phenotypes,” or “phenologs,” are examples of deep homology, and may be used to predict additional candidate disease genes.
Results: In this work, we develop an unsupervised algorithm for ranking phenolog-based candidate disease genes through the integration of predictions from the k nearest neighbor phenologs, comparing classifiers and weighting functions by cross-validation. We also improve upon the original method by extending the theory to paralogous phenotypes. Our algorithm makes use of additional phenotype data — from chicken, zebrafish, and E. coli, as well as new datasets for C. elegans — establishing that several types of annotations may be treated as phenotypes. We demonstrate the use of our algorithm to predict novel candidate genes for human atrial fibrillation (such as HRH2, ATP4A, ATP4B, and HOPX) and epilepsy (e.g., PAX6 and NKX2-1). We suggest gene candidates for pharmacologically-induced seizures in mouse, solely based on orthologous phenotypes from E. coli. We also explore the prediction of plant gene–phenotype associations, as for the Arabidopsis response to vernalization phenotype.
Conclusions: We are able to rank gene predictions for a significant portion of the diseases in the Online Mendelian Inheritance in Man database. Additionally, our method suggests candidate genes for mammalian seizures based only on bacterial phenotypes and gene orthology. We demonstrate that phenotype information may come from diverse sources, including drug sensitivities, gene ontology biological processes, and in situ hybridization annotations. Finally, we offer testable candidates for a variety of human diseases, plant traits, and other classes of phenotypes across a wide array of species.Center for Systems and Synthetic BiologyInstitute for Cellular and Molecular [email protected]
The 5-hydroxytryptamine(4a) receptor is palmitoylated at two different sites and acylation is critically involved in regulation of receptor constitutive activity
Energy-momentum balance in quantum dielectrics
We calculate the energy-momentum balance in quantum dielectrics such as
Bose-Einstein condensates. In agreement with the experiment [G. K. Campbell et
al. Phys. Rev. Lett. 94, 170403 (2005)] variations of the Minkowski momentum
are imprinted onto the phase, whereas the Abraham tensor drives the flow of the
dielectric. Our analysis indicates that the Abraham-Minkowski controversy has
its root in the Roentgen interaction of the electromagnetic field in dielectric
media
A repulsive reference potential reproducing the dynamics of a liquid with attractions
A well-known result of liquid state theory is that the structure of dense
fluids is mainly determined by repulsive forces. The WCA potential, which cuts
intermolecular potentials at their minima, is therefore often used as a
reference. However, this reference gives quite wrong results for the viscous
dynamics of the Kob-Andersen binary Lennard-Jones liquid [Berthier and Tarjus,
Phys. Rev. Lett. 103, 170601 (2009)]. We show that repulsive inverse-power law
potentials provide a useful reference for this liquid by reproducing its
structure, dynamics, and isochoric heat capacity
Towards an understanding of isospin violation in pion-nucleon scattering
We investigate isospin breaking in low-energy pion-nucleon scattering in the
framework of chiral perturbation theory. This work extends the systematic
analysis of [1] to the energy range above threshold. Various relations, which
identically vanish in the limit of isospin symmetry, are used to quantify
isospin breaking effects. We study the energy dependence of the S- and P-wave
projections of these ratios and find dramatic effects in the S-waves of those
two relations which are given in terms of isoscalar quantities only. This
effect drops rather quickly with growing center-of-mass energy.Comment: 12 pp, REVTeX, 8 figs, FZJ-IKP(TH)-2000-2
Perfect imaging with positive refraction in three dimensions
Maxwell's fish eye has been known to be a perfect lens within the validity
range of ray optics since 1854. Solving Maxwell's equations we show that the
fish-eye lens in three dimensions has unlimited resolution for electromagnetic
waves
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