1,664 research outputs found
Analytic Examples, Measurement Models and Classical Limit of Quantum Backflow
We investigate the backflow effect in elementary quantum mechanics - the
phenomenon in which a state consisting entirely of positive momenta may have
negative current and the probability flows in the opposite direction to the
momentum. We compute the current and flux for states consisting of
superpositions of gaussian wave packets. These are experimentally realizable
but the amount of backflow is small. Inspired by the numerical results of Penz
et al (M.Penz, G.Gr\"ubl, S.Kreidl and P.Wagner, J.Phys. A39, 423 (2006)), we
find two non-trivial wave functions whose current at any time may be computed
analytically and which have periods of significant backflow, in one case with a
backwards flux equal to about 70 percent of the maximum possible backflow, a
dimensionless number , discovered by Bracken and Melloy
(A.J.Bracken and G.F.Melloy, J.Phys. A27, 2197 (1994)). This number has the
unusual property of being independent of (and also of all other
parameters of the model), despite corresponding to an obviously
quantum-mechanical effect, and we shed some light on this surprising property
by considering the classical limit of backflow. We discuss some specific
measurement models in which backflow may be identified in certain measurable
probabilities.Comment: 33 pages, 14 figures. Minor revisions. Published versio
Combined SEM-FIB-SPM-TOF-EDX-EBSD as a Multifunctional Tool
Extended abstract of a paper presented at Microscopy and Microanalysis 2012 in Phoenix, Arizona, USA, July 29 - August 2, 201
High purity nanoparticles exceed stoichiometry limits in rebox chemistry: the nano way to cleaner water
A potentially cheaper and more effective way of cleaning wastewater has been discovered by scientists
at Nazarbayev University and the University of Brighton researching nanotechnology [1]. It is well
established that when particles are reduced to the nanoscale unexpected effects occur. Silver, for example,
interacts with mercury ions in a fixed ratio of atoms (stoichiometry), typically 2:1, which presents a limit
that has never been exceeded. In this project we used an alternative chemical procedure based on modified
quartz sand to immobilise silver nanoparticles (NPs) with control over their size. We found that when the
size of the silver NPs decreased below 35 nm the amount of mercury ions reacting with silver increased
beyond the long-held limit and rose to a maximum of 1:1.2 for 10 nm sized silver
Cellular location and activity of Escherichia coli RecG proteins shed light on the function of its structurally unresolved C-terminus
RecG is a DNA translocase encoded by most species of bacteria. The Escherichia coli protein targets branched DNA substrates and drives the unwinding and rewinding of DNA strands. Its ability to remodel replication forks and to genetically interact with PriA protein have led to the idea that it plays an important role in securing faithful genome duplication. Here we report that RecG co-localises with sites of DNA replication and identify conserved arginine and tryptophan residues near its C-terminus that are needed for this localisation. We establish that the extreme C-terminus, which is not resolved in the crystal structure, is vital for DNA unwinding but not for DNA binding. Substituting an alanine for a highly conserved tyrosine near the very end results in a substantial reduction in the ability to unwind replication fork and Holliday junction structures but has no effect on substrate affinity. Deleting or substituting the terminal alanine causes an even greater reduction in unwinding activity, which is somewhat surprising as this residue is not uniformly present in closely related RecG proteins. More significantly, the extreme C-terminal mutations have little effect on localisation. Mutations that do prevent localisation result in only a slight reduction in the capacity for DNA repair. © 2014 The Author(s)
Polyurea-Functionalized Multiwalled Carbon Nanotubes
An in situ polycondensation approach was applied to functionalize multiwalled carbon nanotubes (MWNTs), resulting in various linear or hyperbranched polycondensed polymers [e.g., polyureas, polyurethanes, and poly(urea-urethane)-bonded carbon nanotubes]. The quantity of the grafted polymer can be easily controlled by the feed ratio of monomers. As a typical example, the polyurea-functionalized MWNTs were measured and characterized in detail. The oxidized MWNTs (MWNT-COOH) were converted into acyl chloride-functionalized MWNTs (MWNT-COCl) by reaction with neat thionyl chloride (SOCl2). MWNT-COCl was reacted with excess 1,6-diaminohexane, affording amino-functionalized MWNTs (MWNT-NH2). In the presence of MWNT-NH2, the polyurea was covalently coated onto the surfaces of the nanotube by in situ polycondensation of diisocyanate [e.g., 4,4‘-methylenebis(phenylisocyanate)] and 1,6-diaminohexane, followed by the removal of free polymer via repeated filtering and solvent washing. The coated polyurea content can be controlled to some extent by adjusting the feed ratio of the isocyanato and amino groups. The structure and morphology of the resulting nanocomposites were characterized by FTIR, NMR, Raman, confocal Raman, TEM, EDS, and SEM measurements. The polyurea-coated MWNTs showed interesting self-assembled flat- or flowerlike morphologies in the solid state. The signals corresponding to that of the D and G bands of the carbon nanotubes were strongly attenuated after polyurea was chemically tethered to the MWNT surfaces. Comparative experiments showed that the grafted polymer species and structures have a strong effect on the Raman signals of polymer-functionalized MWNTs
Reduction of intra- and interlaboratory variation in CD34+ stem cell enumeration using stable test material, standard protocols and targeted training
Reputation Agent: Prompting Fair Reviews in Gig Markets
Our study presents a new tool, Reputation Agent, to promote fairer reviews
from requesters (employers or customers) on gig markets. Unfair reviews,
created when requesters consider factors outside of a worker's control, are
known to plague gig workers and can result in lost job opportunities and even
termination from the marketplace. Our tool leverages machine learning to
implement an intelligent interface that: (1) uses deep learning to
automatically detect when an individual has included unfair factors into her
review (factors outside the worker's control per the policies of the market);
and (2) prompts the individual to reconsider her review if she has incorporated
unfair factors. To study the effectiveness of Reputation Agent, we conducted a
controlled experiment over different gig markets. Our experiment illustrates
that across markets, Reputation Agent, in contrast with traditional approaches,
motivates requesters to review gig workers' performance more fairly. We discuss
how tools that bring more transparency to employers about the policies of a gig
market can help build empathy thus resulting in reasoned discussions around
potential injustices towards workers generated by these interfaces. Our vision
is that with tools that promote truth and transparency we can bring fairer
treatment to gig workers.Comment: 12 pages, 5 figures, The Web Conference 2020, ACM WWW 202
Trends in Kaposi's sarcoma-associated Herpesvirus antibodies prior to the development of HIV-associated Kaposi's sarcoma: a nested case-control study.
HIV-associated Kaposi's sarcoma (KS) is a public health challenge in sub-Saharan Africa since both the causative agent, Kaposi's sarcoma associated-herpesvirus (KSHV), and the major risk factor, HIV, are prevalent. In a nested case-control study within a long-standing clinical cohort in rural Uganda, we used stored sera to examine the evolution of antibody titres against the KSHV antigens K8.1 and latency-associated nuclear antigen (LANA) among 30 HIV-infected subjects who subsequently developed HIV-related KS (cases) and among 108 matched HIV/KSHV coinfected controls who did not develop KS. Throughout the 6 years prior to diagnosis, antibody titres to K8.1 and LANA were significantly higher among cases than controls (p < 0.0001), and titres increased prior to diagnosis in the cases. K8.1 titres differed more between KS cases and controls, compared to LANA titres. These differences in titre between cases and controls suggest a role for lytic viral replication in the pathogenesis of HIV-related KS in this setting
Robot rights? Towards a social-relational justification of moral consideration \ud
Should we grant rights to artificially intelligent robots? Most current and near-future robots do not meet the hard criteria set by deontological and utilitarian theory. Virtue ethics can avoid this problem with its indirect approach. However, both direct and indirect arguments for moral consideration rest on ontological features of entities, an approach which incurs several problems. In response to these difficulties, this paper taps into a different conceptual resource in order to be able to grant some degree of moral consideration to some intelligent social robots: it sketches a novel argument for moral consideration based on social relations. It is shown that to further develop this argument we need to revise our existing ontological and social-political frameworks. It is suggested that we need a social ecology, which may be developed by engaging with Western ecology and Eastern worldviews. Although this relational turn raises many difficult issues and requires more work, this paper provides a rough outline of an alternative approach to moral consideration that can assist us in shaping our relations to intelligent robots and, by extension, to all artificial and biological entities that appear to us as more than instruments for our human purpose
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Flow-induced dynamic surface tension effects at nanoscale
The aim of this study is to investigate flow-induced dynamic surface tension effects, similar to the well-known Marangoni phenomena, but solely generated by the nanoscale topography of the substrates. The flow-induced surface tension effects are examined on the basis of a sharp interface theory. It is demonstrated how nanoscale objects placed at the boundary of the flow domain result in the generation of substantial surface forces acting on the bulk flow
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