Dynamic Normalization for Compact Binary Coalescence Searches in Non-Stationary Noise

The output of gravitational-wave interferometers, such as LIGO and Virgo, can be highly non-stationary. Broadband detector noise can affect the detector sensitivity on the order of tens of seconds. Gravitational-wave transient searches, such as those for colliding black holes, estimate this noise in order to identify gravitational-wave events. During times of non-stationarity we see a higher rate of false events being reported. To accurately separate signal from noise, it is imperative to incorporate the changing detector state into gravitational-wave searches. We develop a new statistic which estimates the variation of the interferometric detector noise. We use this statistic to re-rank candidate events identified during LIGO-Virgo's second observing run by the PyCBC search pipeline. This results in a 7% improvement in the sensitivity volume for low mass binaries, particularly binary neutron stars mergers

The c-terminal extension of a hybrid immunoglobulin A/G heavy chain is responsible for its Golgi-mediated sorting to the vacuole

We have assessed the ability of the plant secretory pathway to handle the expression of complex heterologous proteins by investigating the fate of a hybrid immunoglobulin A/G in tobacco cells. Although plant cells can express large amounts of the antibody, a relevant proportion is normally lost to vacuolar sorting and degradation. Here we show that the synthesis of high amounts of IgA/G does not impose stress on the plant secretory pathway. Plant cells can assemble antibody chains with high efficiency and vacuolar transport occurs only after the assembled immunoglobulins have traveled through the Golgi complex. We prove that vacuolar delivery of IgA/G depends on the presence of a cryptic sorting signal in the tailpiece of the IgA/G heavy chain. We also show that unassembled light chains are efficiently secreted as monomers by the plant secretory pathway

Improving the Sensitivity of Advanced LIGO Using Noise Subtraction

This paper presents an adaptable, parallelizable method for subtracting linearly coupled noise from Advanced LIGO data. We explain the features developed to ensure that the process is robust enough to handle the variability present in Advanced LIGO data. In this work, we target subtraction of noise due to beam jitter, detector calibration lines, and mains power lines. We demonstrate noise subtraction over the entirety of the second observing run, resulting in increases in sensitivity comparable to those reported in previous targeted efforts. Over the course of the second observing run, we see a 30% increase in Advanced LIGO sensitivity to gravitational waves from a broad range of compact binary systems. We expect the use of this method to result in a higher rate of detected gravitational-wave signals in Advanced LIGO data.Comment: 15 pages, 6 figure

Large-Scale Image Processing with the ROTSE Pipeline for Follow-Up of Gravitational Wave Events

Electromagnetic (EM) observations of gravitational-wave (GW) sources would bring unique insights into a source which are not available from either channel alone. However EM follow-up of GW events presents new challenges. GW events will have large sky error regions, on the order of 10-100 square degrees, which can be made up of many disjoint patches. When searching such large areas there is potential contamination by EM transients unrelated to the GW event. Furthermore, the characteristics of possible EM counterparts to GW events are also uncertain. It is therefore desirable to be able to assess the statistical significance of a candidate EM counterpart, which can only be done by performing background studies of large data sets. Current image processing pipelines such as that used by ROTSE are not usually optimised for large-scale processing. We have automated the ROTSE image analysis, and supplemented it with a post-processing unit for candidate validation and classification. We also propose a simple ad hoc statistic for ranking candidates as more likely to be associated with the GW trigger. We demonstrate the performance of the automated pipeline and ranking statistic using archival ROTSE data. EM candidates from a randomly selected set of images are compared to a background estimated from the analysis of 102 additional sets of archival images. The pipeline's detection efficiency is computed empirically by re-analysis of the images after adding simulated optical transients that follow typical light curves for gamma-ray burst afterglows and kilonovae. We show that the automated pipeline rejects most background events and is sensitive to simulated transients to limiting magnitudes consistent with the limiting magnitude of the images

Statistical Communication Theory

Contains research objectives and reports on three research projects

Statistical Communication Theory

Contains reports on four research projects

Розробка модуля Ethernet контролю для дистанційного керування електроживильною установкою

Sound processing in the inner ear involves separation of the constituent frequencies along the length of the cochlea. Frequencies relevant to human speech (100 to 500 Hz) are processed in the apex region. Among mammals, the guinea pig cochlear apex processes similar frequencies and is thus relevant for the study of speech processing in the cochlea. However, the requirement for extensive surgery has challenged the optical accessibility of this area to investigate cochlear processing of signals without significant intrusion. A simple method is developed to provide optical access to the guinea pig cochlear apex in two directions with minimal surgery. Furthermore, all prior vibration measurements in the guinea pig apex involved opening an observation hole in the otic capsule, which has been questioned on the basis of the resulting changes to cochlear hydrodynamics. Here, this limitation is overcome by measuring the vibrations through the unopened otic capsule using phase-sensitive Fourier domain optical coherence tomography. The optically and surgically advanced method described here lays the foundation to perform minimally invasive investigation of speech-related signal processing in the cochlea. (C) The Authors. Published by SPIE under a Creative Commons Attribution 3.0 Unported License.Funding Agencies|NIH NIDCD [R01DC000141]; NIH [R01DC004554, R01DC010201, R01DC011796]; Swedish Research Council [K2014-63X-14061-14-5]; Torsten Soderberg Foundation</p

Electromagnetic follow-up of gravitational wave transient signal candidates

Pioneering efforts aiming at the development of multi-messenger gravitational wave and electromagnetic astronomy have been made. An electromagnetic observation follow-up program of candidate gravitational wave events has been performed (Dec 17 2009 to Jan 8 2010 and Sep 4 to Oct 20 2010) during the recent runs of the LIGO and Virgo gravitational wave detectors. It involved ground-based and space electromagnetic facilities observing the sky at optical, X-ray and radio wavelengths. The joint gravitational wave and electromagnetic observation study requires the development of specific image analysis procedures able to discriminate the possible electromagnetic counterpart of gravitational wave triggers from contaminant/background events. The paper presents an overview of the electromagnetic follow-up program and the image analysis procedures.Comment: Proceedings of the 12th International Conference on "Topics in Astroparticle and Underground Physics" (TAUP 2011), Munich, September 2011 (to appear in IoP Journal of Physics: Conference Series

Cost-benefit analysis for commissioning decisions in GEO600

Gravitational wave interferometers are complex instruments, requiring years of commissioning to achieve the required sensitivities for the detection of gravitational waves, of order 10^-21 in dimensionless detector strain, in the tens of Hz to several kHz frequency band. Investigations carried out by the GEO600 detector characterisation group have shown that detector characterisation techniques are useful when planning for commissioning work. At the time of writing, GEO600 is the only large scale laser interferometer currently in operation running with a high duty factor, 70%, limited chiefly by the time spent commissioning the detector. The number of observable gravitational wave sources scales as the product of the volume of space to which the detector is sensitive and the observation time, so the goal of commissioning is to improve the detector sensitivity with the least possible detector down time. We demonstrate a method for increasing the number of sources observable by such a detector, by assessing the severity of non-astrophysical noise contaminations to efficiently guide commissioning. This method will be particularly useful in the early stages and during the initial science runs of the aLIGO and adVirgo detectors, as they are brought up to design performance.Comment: 17 pages, 17 figures, 2 table