1,717 research outputs found

    Some statistics on permutations avoiding generalized patterns

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    In the last decade a huge amount of articles has been published studying pattern avoidance on permutations. From the point of view of enumeration, typically one tries to count permutations avoiding certain patterns according to their lengths. Here we tackle the problem of refining this enumeration by considering the statistics "first/last entry". We give complete results for every generalized patterns of type (1,2)(1,2) or (2,1)(2,1) as well as for some cases of permutations avoiding a pair of generalized patterns of the above types.Comment: 5 figure

    The surface accessibility of α-bungarotoxin monitored by a novel paramagnetic probe

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    The surface accessibility of {alpha}-bungarotoxin has been investigated by using Gd2L7, a newly designed paramagnetic NMR probe. Signal attenuations induced by Gd2L7 on {alpha}-bungarotoxin C{alpha}H peaks of 1H-13C HSQC spectra have been analyzed and compared with the ones previously obtained in the presence of GdDTPA-BMA. In spite of the different molecular size and shape, for the two probes a common pathway of approach to the {alpha}-bungarotoxin surface can be observed with an equally enhanced access of both GdDTPA-BMA and Gd2L7 towards the protein surface side where the binding site is located. Molecular dynamics simulations suggest that protein backbone flexibility and surface hydration contribute to the observed preferential approach of both gadolinium complexes specifically to the part of the {alpha}-bungarotoxin surface which is involved in the interaction with its physiological target, the nicotinic acetylcholine receptor

    On the functional design of the DTU10 MW wind turbine scale model of LIFES50+ project

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    This paper illustrates the mechatronic design of the wind tunnel scale model of the DTU 10MW reference wind turbine, for the LIFES50+ H2020 European project. This model was designed with the final goal of controlling the angle of attack of each blade by means of miniaturized servomotors, for implementing advanced individual pitch control (IPC) laws on a Floating Offshore Wind Turbine (FOWT) 1/75 scale model. Many design constraints were to be respected: among others, the rotor-nacelle overall mass due to aero-elastic scaling, the limited space of the nacelle, where to put three miniaturized servomotors and the main shaft one, with their own inverters/controllers, the slip rings for electrical rotary contacts, the highest stiffness as possible for the nacelle support and the blade-rotor connections, for ensuring the proper kinematic constraint, considering the first flapwise blade natural frequency, the performance of the servomotors to guarantee the wide frequency band due to frequency scale factors, etc. The design and technical solutions are herein presented and discussed, along with an overview of the building and verification process. Also a discussion about the goals achieved and constraints respected for the rigid wind turbine scale model (LIFES50+ deliverable D.3.1) and the further possible improvements for the IPC-aero-elastic scale model, which is being finalized at the time of this paper

    Taxonomia de solos desenvolvidos sobre depósitos sedimentares da Formação Solimões no Estado do Acre.

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    Os solos do Estado do Acre na maioria são formados sobre material de origem com grande influência da orogênese Andina, com elevados teores de Ca2+, Mg2+ e Al3+ concomitantemente, associado às combinações diferenciadas dos valores da CTC, V e m. O objetivo deste trabalho foi caracterizar e classificar os solos de uma topossequência sobre material sedimentar da Formação Solimões, no município de Feijó, Acre. Foram abertas trincheiras em três pontos de uma topossequência: terço superior (P1), terço médio (P2) e terço inferior (P3). Os solos foram analisados quanto a morfologia, granulometria (areia, silte e argila), complexo sortivo (Ca2+, Mg2+, Na+, K+ e Al3+), acidez potencial (H+Al), P assimilável, pH (água e KCl), superfície específica, ataque sulfúrico (óxidos de Fe, Al, Ti e Si), mineralogia (frações areia, silte e argila). Os solos foram classificados segundo o Sistema Brasileiro de Classificação de Solos (SiBCS, 2006) e apresentada uma proposta de classificação considerando as peculiaridades do solos da região. Os solos têm baixo grau de desenvolvimento pedogenético, com minerais da fração argila de alta atividade, além da presença de minerais primários, como feldspatos e plagioclásios, nas frações areia e silte. Os solos foram classificados segundo o SiBCS atual como Argissolo Vermelho Álitico plíntico (P1), Argissolo Acinzentado Distrófico plíntico (P2) e Cambissolo Háplico Ta Eutrófico típico (P3)

    Quantification of aluminium in soil of the Solimões formation, Acre State, Brazil.

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    The variety of soils in the State of Acre is wide and their chemical profiles are still not fully understood. The nature of the material of origin of these soils is indicated by the high aluminium (Al) content, commonly associated with high calcium (Ca) and magnesium (Mg) contents. The study objective was to use different methods to quantify Al in soils from toposequences formed from material of a sedimentary nature originating from the Solimões Formation, in Acre, Brazil. Trenches were opened at three distinct points in the landscape: shoulder, backslope and footslope positions. Soil samples were collected for physical, chemical, mineralogical analyses. The Al content was quantified using different methods. High Al contents were found in most of these horizons, associated with high Ca and Mg levels, representing the predominant cations in the sum of exchangeable bases. The mineralogy indicates that the soils are still in a low weathering phase, with the presence of significant quantities of 2:1 minerals. Similar Al contents were determined by the methods of NaOH titration, xylenol orange spectrometry and inductively coupled plasma optical emission spectrometry. However, no consistent data were obtained by the pyrocatechol violet method. Extraction with KCl overestimated the exchangeable Al content due to its ability to extract the non-exchangeable Al present in the smectite interlayers. It was observed that high Al contents are related to the instability of the hydroxyl-Al smectite interlayers

    UNAFLOW project: UNsteady Aerodynamics of FLOating Wind turbines

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    UNAFLOW (UNsteady Aerodynamics for Floating Wind) is a joint EU-IRPWIND founded experiment on wind turbine rotor unsteady aerodynamics. It brings together four different academic contributors: Energy research Centre of the Netherlands (ECN), DTU Wind Energy, University of Stuttgart (USTUTT) and Politecnico di Milano (PoliMi) sharing knowledge both in numerical modelling and in experimental tests design, allowing direct numerical and experimental comparison. The experimental tests carried out for UNAFLOW are of the same type of the ones carried out during the ongoing EU H2020 project LIFES50+ [1], regarding both the unsteady behaviour of the 2d blade section and the entire turbine rotor, although with improved setup and wider test matrix. The project partners are already currently jointly collaborating in the AVATAR project [2], developing and validating numerical models of different accuracy level. The numerical models used in the UNALFOW project range from engineering tool (eg. BEM) to high fidelity CFD methods. Numerical simulations are used both in the design of experiment phase and in the results analysis allowing for an in depth understanding of the experimental findings through advanced modelling approach. The UNAFLOW project, together with a new understanding of the unsteady behaviour of the turbine rotor aerodynamics, will provide also an open database to be shared among the scientific community for future analysis and new models validation

    Alterations in vascular function in primary aldosteronism - a cardiovascular magnetic resonance imaging study

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    Introduction: Excess aldosterone is associated with increased cardiovascular risk. Aldosterone has a permissive effect on vascular fibrosis. Cardiovascular magnetic resonance imaging (CMR) allows study of vascular function by measuring aortic distensibility. We compared aortic distensibility in primary aldosteronism (PA), essential hypertension (EH) and normal controls and explored the relationship between aortic distensibility and pulse wave velocity (PWV).<p></p> Methods: We studied PA (n=14) and EH (n=33) subjects and age-matched healthy controls (n=17) with CMR, including measurement of aortic distensibility, and measured PWV using applanation tonometry. At recruitment, PA and EH patients had similar blood pressure and left ventricular mass.<p></p> Results: Subjects with PA had significantly lower aortic distensibilty and higher PWV compared to EH and healthy controls. These changes were independent of other factors associated with reduced aortic distensibility, including aging. There was a significant relationship between increasing aortic stiffness and age in keeping with physical and vascular aging. As expected, aortic distensibility and PWV were closely correlated.<p></p> Conclusion: These results demonstrate that PA patients display increased arterial stiffness compared to EH, independent of vascular aging. The implication is that aldosterone invokes functional impairment of arterial function. The long-term implications of arterial stiffening in aldosterone excess require further study.<p></p&gt
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