Mutation-aware fault prediction

We introduce mutation-aware fault prediction, which leverages additional guidance from metrics constructed in terms of mutants and the test cases that cover and detect them. We report the results of 12 sets of experiments, applying 4 di↵erent predictive modelling techniques to 3 large real world systems (both open and closed source). The results show that our proposal can significantly (p 0.05) improve fault prediction performance. Moreover, mutation based metrics lie in the top 5% most frequently relied upon fault predictors in 10 of the 12 sets of experiments, and provide the majority of the top ten fault predictors in 9 of the 12 sets of experiments.http://www0.cs.ucl.ac.uk/staff/F.Sarro/resource/papers/ISSTA2016-Bowesetal.pd

Computational classifiers for predicting the short-term course of Multiple sclerosis

The aim of this study was to assess the diagnostic accuracy (sensitivity and specificity) of clinical, imaging and motor evoked potentials (MEP) for predicting the short-term prognosis of multiple sclerosis (MS). METHODS: We obtained clinical data, MRI and MEP from a prospective cohort of 51 patients and 20 matched controls followed for two years. Clinical end-points recorded were: 1) expanded disability status scale (EDSS), 2) disability progression, and 3) new relapses. We constructed computational classifiers (Bayesian, random decision-trees, simple logistic-linear regression-and neural networks) and calculated their accuracy by means of a 10-fold cross-validation method. We also validated our findings with a second cohort of 96 MS patients from a second center. RESULTS: We found that disability at baseline, grey matter volume and MEP were the variables that better correlated with clinical end-points, although their diagnostic accuracy was low. However, classifiers combining the most informative variables, namely baseline disability (EDSS), MRI lesion load and central motor conduction time (CMCT), were much more accurate in predicting future disability. Using the most informative variables (especially EDSS and CMCT) we developed a neural network (NNet) that attained a good performance for predicting the EDSS change. The predictive ability of the neural network was validated in an independent cohort obtaining similar accuracy (80%) for predicting the change in the EDSS two years later. CONCLUSIONS: The usefulness of clinical variables for predicting the course of MS on an individual basis is limited, despite being associated with the disease course. By training a NNet with the most informative variables we achieved a good accuracy for predicting short-term disability

User enhanceability for fast response to changing office needs

Key factors for developing user enhanceable office systems are: (i) an appropriate office model as a basis for office application systems; (ii) easily comprehensible visual formalisms to overcome the need for conventional programming. This paper proposes a method for user enhanceability that uses a distributed agent-based office model and a novel multi-paradigm visual programming language. To support dynamic organizations, the office model focusses on the organizational knowledge necessary to facilitate operative changes such as workload re-distributing and dynamic work-flow management. The visual language is designed to explicitly represent this organizational knowledge during all stages of the development