Seismotectonics of the active thrust front in southwestern Sicily: hints on the Belice and Selinunte seismogenic sources

We present a seismotectonic model of the active thrust front in western Sicily, which includes the area hit by the 1968 Belice earthquake sequence. The ~40 km long South-WEstern Sicilian Thrust (SWEST) is formed by two aligned albeit non-parallel fault arrays, the Granitola-Castelevetrano Thrust System (GCTS) in the west and the Partanna- Poggioreale Thrust System (PPTS) in the east. The ~NE-SW trending, NW-dipping GCTS straddles from the Pelagian coastline to Castelvetrano, is ~18 km long and composed of two segments, with the northern, ~12 km long one showing geodetic and geologic evidence of active deformation (Barreca et al., 2014). The segment is marked by a sharp gradient in Differential SAR interferometry (DinSAR and STAMPs) and GPS velocity fields. Geologic evidence include an up to 60 m high, and up to 15° steep scarp, which is the fore-limb of a broad fold involving Lower Pleistocene shore calcarenites, and cm-scale reverse displacement of an ancient road dated as early Bronze-Hellenistic age. Inversion of fault slip-lineation data from structures displacing the archaeological remains yields a ~N110°E shortening axis, consistent with the geodetic shortening direction estimated from GPS differential velocities. The ~ENE-WSW trending PPTS stretches from Partanna to the macro-seismic area of the 1968 earthquake sequence and is composed of two ~10 km long segments limited by relay ramps. Although geologic and geodetic evidence of deformation are less clear than for the GCTS, we nonetheless observe a gradient in interferometry data for the western segment, and evidence of slow deformation (creep?) in historical to recent (last ~400 yr?) man-made structures. Integration of geologic, geodetic and seismology data suggests the active folds and thrusts are the uppermost expression of steep (45°) crustal ramps (Monaco et al., 1996) which upthrust the Saccense platform at depth. Based on macroseismic and seismological evidence (Monaco et al., 1996), we contend that the PPTS was partly activated during the 1968 sequence, and that rupture stopped at the junction with the GCTS. The current geodetic strain accumulation on the GCTS, on the other hand, suggests that the fault array has been significantly loaded, and that its last important co-seismic event could have been caused the 4th–5th century A.D. destruction of Selinunte (Bottari et al., 2009)

Geodetic and geological evidence of active tectonics in south-westernSicily (Italy)

Integrated geological, geodetic and marine geophysical data provide evidence of active deformation insouth-western Sicily, in an area spatially coincident with the macroseismic zone of the destructive 1968Belice earthquake sequence. Even though the sequence represents the strongest seismic event recordedin Western Sicily in historical times, focal solutions provided by different authors are inconclusive onpossible faulting mechanism, which ranges from thrusting to transpression, and the seismogenic sourceis still undefined. Interferometric (DInSAR) observations reveal a differential ground motion on a SW–NEalignment between Campobello di Mazara and Castelvetrano (CCA), located just west of the maximummacroseismic sector. In addition, new GPS campaign-mode data acquired across the CCA alignment doc-uments NW–SE contractional strain accumulation. Morphostructural analysis allowed to associate thealignment detected through geodetic measurements with a topographic offset of Pleistocene marine sed-iments. The on-land data were complemented by new high-resolution marine geophysical surveys, whichindicate recent contraction on the offshore extension of the CCA alignment. The discovery of archaeo-logical remains displaced by a thrust fault associated with the alignment provided the first likely surfaceevidence of coseismic and/or aseismic deformation related to a seismogenic source in the area. Resultsof the integrated study supports the contention that oblique thrusting and folding in response to NW–SEoriented contraction is still active. Although we are not able to associate the CCA alignment to the 1968seismic sequence or to the historical earthquakes that destroyed the ancient Greek city of Selinunte,located on the nearby coastline, our result must be incorporated in the seismic hazard evaluation of thisdensely populated area of Sicily

Algebraic Comparison of Partial Lists in Bioinformatics

The outcome of a functional genomics pipeline is usually a partial list of genomic features, ranked by their relevance in modelling biological phenotype in terms of a classification or regression model. Due to resampling protocols or just within a meta-analysis comparison, instead of one list it is often the case that sets of alternative feature lists (possibly of different lengths) are obtained. Here we introduce a method, based on the algebraic theory of symmetric groups, for studying the variability between lists ("list stability") in the case of lists of unequal length. We provide algorithms evaluating stability for lists embedded in the full feature set or just limited to the features occurring in the partial lists. The method is demonstrated first on synthetic data in a gene filtering task and then for finding gene profiles on a recent prostate cancer dataset

Can We Really Prevent Suicide?

Every year, suicide is among the top 20 leading causes of death globally for all ages. Unfortunately, suicide is difficult to prevent, in large part because the prevalence of risk factors is high among the general population. In this review, clinical and psychological risk factors are examined and methods for suicide prevention are discussed. Prevention strategies found to be effective in suicide prevention include means restriction, responsible media coverage, and general public education, as well identification methods such as screening, gatekeeper training, and primary care physician education. Although the treatment for preventing suicide is difficult, follow-up that includes pharmacotherapy, psychotherapy, or both may be useful. However, prevention methods cannot be restricted to the individual. Community, social, and policy interventions will also be essentia

Landscape structure affects the prevalence and distribution of a tick-borne zoonotic pathogen

Background Landscape structure can affect pathogen prevalence and persistence with consequences for human and animal health. Few studies have examined how reservoir host species traits may interact with landscape structure to alter pathogen communities and dynamics. Using a landscape of islands and mainland sites we investigated how natural landscape fragmentation affects the prevalence and persistence of the zoonotic tick-borne pathogen complex Borrelia burgdorferi(sensu lato), which causes Lyme borreliosis. We hypothesized that the prevalence of B. burgdorferi (s.l.) would be lower on islands compared to the mainland and B. afzelii, a small mammal specialist genospecies, would be more affected by isolation than bird-associated B. garinii and B. valaisiana and the generalist B. burgdorferi (sensu stricto). Methods Questing (host-seeking) nymphal I. Ricinus ticks (n = 6567) were collected from 12 island and 6 mainland sites in 2011, 2013 and 2015 and tested for B. burgdorferi(s.l.). Deer abundance was estimated using dung transects. Results The prevalence of B. burgdorferi (s.l.) was significantly higher on the mainland (2.5%, 47/1891) compared to island sites (0.9%, 44/4673) (P < 0.01). While all four genospecies of B. burgdorferi (s.l.) were detected on the mainland, bird-associated species B. garinii and B. valaisiana and the generalist genospecies B. burgdorferi(s.s.) predominated on islands. Conclusion We found that landscape structure influenced the prevalence of a zoonotic pathogen, with a lower prevalence detected among island sites compared to the mainland. This was mainly due to the significantly lower prevalence of small mammal-associated B. afzelii. Deer abundance was not related to pathogen prevalence, suggesting that the structure and dynamics of the reservoir host community underpins the observed prevalence patterns, with the higher mobility of bird hosts compared to small mammal hosts leading to a relative predominance of the bird-associated genospecies B. garinii and generalist genospecies B. burgdorferi (s.s.) on islands. In contrast, the lower prevalence of B. afzelii on islands may be due to small mammal populations there exhibiting lower densities, less immigration and stronger population fluctuations. This study suggests that landscape fragmentation can influence the prevalence of a zoonotic pathogen, dependent on the biology of the reservoir host

Upper limb children action-observation training (UP-CAT): a randomised controlled trial in Hemiplegic Cerebral Palsy

BACKGROUND: Rehabilitation for children with hemiplegic cerebral palsy (HCP) aimed to improve function of the impaired upper limb (UL) uses a wide range of intervention programs. A new rehabilitative approach, called Action-Observation Therapy, based on the recent discovery of mirror neurons, has been used in adult stroke but not in children. The purpose of the present study is to design a randomised controlled trial (RCT) for evaluating the efficacy of Action-Observation Therapy in improving UL activity in children with HCP.METHODS/DESIGN: The trial is designed according to CONSORT Statement. It is a randomised, evaluator-blinded, match-pair group trial. Children with HCP will be randomised within pairs to either experimental or control group. The experimental group will perform an Action-Observation Therapy, called UP-CAT (Upper Limb-Children Action-Observation Training) in which they will watch video sequences showing goal-directed actions, chosen according to children UL functional level, combined with motor training with their hemiplegic UL. The control group will perform the same tailored actions after watching computer games. A careful revision of psychometric properties of UL outcome measures for children with hemiplegia was performed. Assisting Hand Assessment was chosen as primary measure and, based on its calculation power, a sample size of 12 matched pairs was established. Moreover, Melbourne and ABILHAND-Kids were included as secondary measures. The time line of assessments will be T0 (in the week preceding the onset of the treatment), T1 and T2 (in the week after the end of the treatment and 8 weeks later, respectively). A further assessment will be performed at T3 (24 weeks after T1), to evaluate the retention of effects. In a subgroup of children enrolled in both groups functional Magnetic Resonance Imaging, exploring the mirror system and sensory-motor function, will be performed at T0, T1 and T2.DISCUSSION: The paper aims to describe the methodology of a RCT for evaluating the efficacy of Action-Observation Therapy in improving UL activity in children with hemiplegia. This study will be the first to test this new type of treatment in childhood. The paper presents the theoretical background, study hypotheses, outcome measures and trial methodology

Early motor signs of attention-deficit hyperactivity disorder: a systematic review

ADHD is a common neurodevelopmental disorder with onset of symptoms typically in early childhood. First signs of the disorder, including language delay, motor delay and temperament characteristics, may be evident as early as infancy. The present review describes published evidence about early motor signs of either children with later symptoms of ADHD or a later diagnosis of the disorder. Nine published cohort studies were included after a systematic search of related terms in PubMed and PsycInfo databases. Study eligibility criteria included: (1) report on early motor function or any motor-related signs; (2) the presence of a participants’ assessment by/at 12 months of age; (3) report of a later presence of ADHD symptoms. The limited number of reports included suggests an association between mild early neurological markers and later developmental coordination disorder and motor overflow movements. Unfortunately, due to their small sample sizes and focus on group reports rather than individuals, they have limited power to find strong associations. Early motor indicators of ADHD, if present, appear to be non-specific, and therefore not yet useful in clinical screening. Spontaneous motility seems to be a promising measure for early ADHD detection, although further studies with large cohorts are recommended to determine its clinical role in children at risk for ADHD

Geologic Map of the Shakespeare Quadrangle (H03), Mercury

A 1:3M geological map of the H03 Shakespeare quadrangle of Mercury has been compiled through photointerpretation of the MESSENGER images. The most prominent geomorphological feature is the Caloris basin, the largest impact crater on Mercury