598 research outputs found
Comparative methods of cleaning meat cutting tables
Digitized 2007 AES.Includes bibliographical references (page 8)
Dehydrated pork studies : removal of glucose by yeast fermentation
This bulletin reports research undertaken in cooperation with the Quarter-master Food and Container Institute for the Armed Forces, and has been assigned number 571 in the series of papers approved for publication...--P. [2].Digitized 2007 AES.Includes bibliographical references (page 12)
Microflora of prepackaged luncheon meats
Digitized 2007 AES.Includes bibliographical references (page 20)
Decisionmaking in practice: The dynamics of muddling through
An alternative to conventional models that treat decisions as open-loop independent choices is presented. The alterative model is based on observations of work situations such as healthcare, where decisionmaking is more typically a closed-loop, dynamic, problem-solving process. The article suggests five important distinctions between the processes assumed by conventional models and the reality of decisionmaking in practice. It is suggested that the logic of abduction in the form of an adaptive,muddling through process is more consistent with the realities of practice in domains such as healthcare.The practical implication is that the design goal should not be to improve consistency with normativemodels of rationality, but to tune the representations guiding the muddling process to increase functional perspicacity
Single Stranded DNA Translocation Through A Nanopore: A Master Equation Approach
We study voltage driven translocation of a single stranded (ss) DNA through a
membrane channel. Our model, based on a master equation (ME) approach,
investigates the probability density function (pdf) of the translocation times,
and shows that it can be either double or mono-peaked, depending on the system
parameters. We show that the most probable translocation time is proportional
to the polymer length, and inversely proportional to the first or second power
of the voltage, depending on the initial conditions. The model recovers
experimental observations on hetro-polymers when using their properties inside
the pore, such as stiffness and polymer-pore interaction.Comment: 7 pages submitted to PR
Butterflies, Busy Weekends, and Chicken Salad: Genetic Criticism and the Output of @Pentametron
Textual analysis places great emphasis on determining the development and direction of authorial intention to illuminate a text’s layers of meaning. How, though, is one to determine the development of authorial intention in a text that appears to remove the traditional human author? This paper explores issues of authorship presented to genetic criticism (critique génétique) by algorithmically-produced texts – that is, texts produced through programmed logic in a computer rather than through direct human agency – such as those of the Twitter bot Pentametron (twitter.com/pentametron). This paper considers the perceived importance of authorship and human agency in the creation of a text. Algorithmic texts challenge contemporary notions of textual creation and development, in turn posing challenges to genetic criticism that are similar to those posed by cut-up texts in other media. This paper argues that Pentametron’s rather nonsensical algorithmic output stresses the reader’s responsibility for meaning-making, and suggests that such algorithmic texts are not so much final texts to be subjected to genetic critique themselves, but are more aptly considered to be forms of avant-texte. These avant-textes serve as inspiration for human-computer symbioses, for re-creations wherein readers make sense out of the seemingly senseless
Evidence-based decision support for pediatric rheumatology reduces diagnostic errors.
BACKGROUND: The number of trained specialists world-wide is insufficient to serve all children with pediatric rheumatologic disorders, even in the countries with robust medical resources. We evaluated the potential of diagnostic decision support software (DDSS) to alleviate this shortage by assessing the ability of such software to improve the diagnostic accuracy of non-specialists.
METHODS: Using vignettes of actual clinical cases, clinician testers generated a differential diagnosis before and after using diagnostic decision support software. The evaluation used the SimulConsult® DDSS tool, based on Bayesian pattern matching with temporal onset of each finding in each disease. The tool covered 5405 diseases (averaging 22 findings per disease). Rheumatology content in the database was developed using both primary references and textbooks. The frequency, timing, age of onset and age of disappearance of findings, as well as their incidence, treatability, and heritability were taken into account in order to guide diagnostic decision making. These capabilities allowed key information such as pertinent negatives and evolution over time to be used in the computations. Efficacy was measured by comparing whether the correct condition was included in the differential diagnosis generated by clinicians before using the software ( unaided ), versus after use of the DDSS ( aided ).
RESULTS: The 26 clinicians demonstrated a significant reduction in diagnostic errors following introduction of the software, from 28% errors while unaided to 15% using decision support (p \u3c 0.0001). Improvement was greatest for emergency medicine physicians (p = 0.013) and clinicians in practice for less than 10 years (p = 0.012). This error reduction occurred despite the fact that testers employed an open book approach to generate their initial lists of potential diagnoses, spending an average of 8.6 min using printed and electronic sources of medical information before using the diagnostic software.
CONCLUSIONS: These findings suggest that decision support can reduce diagnostic errors and improve use of relevant information by generalists. Such assistance could potentially help relieve the shortage of experts in pediatric rheumatology and similarly underserved specialties by improving generalists\u27 ability to evaluate and diagnose patients presenting with musculoskeletal complaints.
TRIAL REGISTRATION: ClinicalTrials.gov ID: NCT02205086
Stochastic volatility and leverage effect
We prove that a wide class of correlated stochastic volatility models exactly
measure an empirical fact in which past returns are anticorrelated with future
volatilities: the so-called ``leverage effect''. This quantitative measure
allows us to fully estimate all parameters involved and it will entail a deeper
study on correlated stochastic volatility models with practical applications on
option pricing and risk management.Comment: 4 pages, 2 figure
Leadership and Culture
This study is about the phenomenon of leadership. Existing studies of leadership have failed to address the complex, multidisciplinary, processual, and collective nature of leadership. Attempts to appear scientific have focused on the forms of leadership rather than its universal processes. Following an analysis of existing theories of leadership viewed from disciplinary frames, the purpose of this study is to propose a new theory of leadership constructed within a cultural frame. The nature of leadership can be understood best when it is defined as a cultural expression containing complex sets of interdependent variables. Insofar as the study presents a cultural theory of leadership, it is informed by anthropology and includes ethnographies as case studies on leadership, including the works of Barth, Leach, Bailey, and Kracke. Inasmuch as the case studies serve to instantiate the proposed theory and the study is founded on the possibility of comparison, integration, and generalization, the research methodology utilized is that of grounded theory as outlined by Glaser and Strauss (1967). The critical properties of both culture and leadership are identified, revealing an isomorphic congruence between the properties of both categories. A comparative analysis between the properties of culture and leadership reveals the coterminous relationship between the two, suggesting leadership is a cultural expression. Among the conclusions drawn are the following: (a) the nature of leadership is linked to the nature of culture; (b) leadership is essentially a cultural expression; (c) the universal dimension of leadership can only be defined in terms of process; and (d) leadership can only be studied as a multidisciplinary phenomenon
Anomalous Dynamics of Translocation
We study the dynamics of the passage of a polymer through a membrane pore
(translocation), focusing on the scaling properties with the number of monomers
. The natural coordinate for translocation is the number of monomers on one
side of the hole at a given time. Commonly used models which assume Brownian
dynamics for this variable predict a mean (unforced) passage time that
scales as , even in the presence of an entropic barrier. However, the time
it takes for a free polymer to diffuse a distance of the order of its radius by
Rouse dynamics scales with an exponent larger than 2, and this should provide a
lower bound to the translocation time. To resolve this discrepancy, we perform
numerical simulations with Rouse dynamics for both phantom (in space dimensions
and 2), and self-avoiding (in ) chains. The results indicate that
for large , translocation times scale in the same manner as diffusion times,
but with a larger prefactor that depends on the size of the hole. Such scaling
implies anomalous dynamics for the translocation process. In particular, the
fluctuations in the monomer number at the hole are predicted to be
non-diffusive at short times, while the average pulling velocity of the polymer
in the presence of a chemical potential difference is predicted to depend on
.Comment: 9 pages, 9 figures. Submitted to Physical Review
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