7 research outputs found

    Research priorities in regional anaesthesia: an international Delphi study.

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    Regional anaesthesia use is growing worldwide, and there is an increasing emphasis on research in regional anaesthesia to improve patient outcomes. However, priorities for future study remain unclear. We therefore conducted an international research prioritisation exercise, setting the agenda for future investigators and funding bodies. We invited members of specialist regional anaesthesia societies from six continents to propose research questions that they felt were unanswered. These were consolidated into representative indicative questions, and a literature review was undertaken to determine if any indicative questions were already answered by published work. Unanswered indicative questions entered a three-round modified Delphi process, whereby 29 experts in regional anaesthesia (representing all participating specialist societies) rated each indicative question for inclusion on a final high priority shortlist. If ≥75% of participants rated an indicative question as 'definitely' include in any round, it was accepted. Indicative questions rated as 'definitely' or 'probably' by <50% of participants in any round were excluded. Retained indicative questions were further ranked based on the rating score in the final Delphi round. The final research priorities were ratified by the Delphi expert group. There were 1318 responses from 516 people in the initial survey, from which 71 indicative questions were formed, of which 68 entered the modified Delphi process. Eleven 'highest priority' research questions were short listed, covering themes of pain management; training and assessment; clinical practice and efficacy; technology and equipment. We prioritised unanswered research questions in regional anaesthesia. These will inform a coordinated global research strategy for regional anaesthesia and direct investigators to address high-priority areas

    Measurement of the Higgs boson production via vector boson fusion and its decay into bottom quarks in proton-proton collisions at √s=13 TeV

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    A measurement of the Higgs boson (H) production via vector boson fusion (VBF) and its decay into a bottom quark-antiquark pair (b (b) over bar) is presented using proton-proton collision data recorded by the CMS experiment at root s = 13TeV and corresponding to an integrated luminosity of 90.8 fb(-1). Treating the gluon-gluon fusion process as a background and constraining its rate to the value expected in the standard model (SM) within uncertainties, the signal strength of the VBF process, defined as the ratio of the observed signal rate to that predicted by the SM, is measured to be mu(qqH)(Hb (b) over bar) = 1.01(-0.46)(+0.55). The VBF signal is observed with a significance of 2.4 standard deviations relative to the background prediction, while the expected significance is 2.7 standard deviations. Considering inclusive Higgs boson production and decay into bottom quarks, the signal strength is measured to be mu(incl.)(Hb (b) over bar) = 0.99(-0.41)(+0.48), corresponding to an observed (expected) significance of 2.6 (2.9) standard deviations

    Measurement of the Higgs boson production via vector boson fusion and its decay into bottom quarks in proton-proton collisions at 1as=13 TeV

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    Abstract: A measurement of the Higgs boson (H) production via vector boson fusion (VBF) and its decay into a bottom quark-antiquark pair (b (b) over bar) is presented using proton-proton collision data recorded by the CMS experiment at root s = 13TeV and corresponding to an integrated luminosity of 90.8 fb(-1). Treating the gluon-gluon fusion process as a background and constraining its rate to the value expected in the standard model (SM) within uncertainties, the signal strength of the VBF process, defined as the ratio of the observed signal rate to that predicted by the SM, is measured to be mu(qqH)(Hb (b) over bar) = 1.01(-0.46)(+0.55). The VBF signal is observed with a significance of 2.4 standard deviations relative to the background prediction, while the expected significance is 2.7 standard deviations. Considering inclusive Higgs boson production and decay into bottom quarks, the signal strength is measured to be mu(incl.)(Hb (b) over bar) = 0.99(-0.41)(+0.48), corresponding to an observed (expected) significance of 2.6 (2.9) standard deviations

    Search for Nonresonant Pair Production of Highly Energetic Higgs Bosons Decaying to Bottom Quarks

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    International audienceA search for nonresonant Higgs boson (H) pair production via gluon and vector boson (V) fusion is performed in the four-bottom-quark final state, using proton-proton collision data at 13 TeV corresponding to 138  fb-1 collected by the CMS experiment at the LHC. The analysis targets Lorentz-boosted H pairs identified using a graph neural network. It constrains the strengths relative to the standard model of the H self-coupling and the quartic VVHH couplings, κ2V, excluding κ2V=0 for the first time, with a significance of 6.3 standard deviations when other H couplings are fixed to their standard model values

    Azimuthal correlations in Z plus jets events in proton-proton collisions at √s=13TeV

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    The production of Z bosons associated with jets is measured in pp collisions at s=13TeV with data recorded with the CMS experiment at the LHC corresponding to an integrated luminosity of 36.3 fb-1 . The multiplicity of jets with transverse momentum pT>30GeV is measured for different regions of the Z boson’s pT(Z) , from lower than 10 GeV to higher than 100 GeV . The azimuthal correlation Δφ between the Z boson and the leading jet, as well as the correlations between the two leading jets are measured in three regions of pT(Z) . The measurements are compared with several predictions at leading and next-to-leading orders, interfaced with parton showers. Predictions based on transverse-momentum dependent parton distributions and corresponding parton showers give a good description of the measurement in the regions where multiple parton interactions and higher jet multiplicities are not important. The effects of multiple parton interactions are shown to be important to correctly describe the measured spectra in the low pT(Z) regions
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