Impact of Inter-Country Distances on International Tourism

Tourism is a worldwide practice with international tourism revenues increasing from US\$495 billion in 2000 to US\$1340 billion in 2017. Its relevance to the economy of many countries is obvious. Even though the World Airline Network (WAN) is global and has a peculiar construction, the International Tourism Network (ITN) is very similar to a random network and barely global in its reach. To understand the impact of global distances on local flows, we map the flow of tourists around the world onto a complex network and study its topological and dynamical balance. We find that although the WAN serves as infrastructural support for the ITN, the flow of tourism does not correlate strongly with the extent of flight connections worldwide. Instead, unidirectional flows appear locally forming communities that shed light on global travelling behaviour inasmuch as there is only a 15% probability of finding bidirectional tourism between a pair of countries. We conjecture that this is a consequence of one-way cyclic tourism by analyzing the triangles that are formed by the network of flows in the ITN. Finally, we find that most tourists travel to neighbouring countries and mainly cover larger distances when there is a direct flight, irrespective of the time it takes

Fractional bioheat equation

In this work we develop a new mathematical model for the Pennes’ bioheat equation assuming a fractional time derivative of single order. A numerical method for the solu- tion of such equations is proposed, and, the suitability of the new model for modelling real physical problems is studied and discussedCOMPETE, FEDER and Fundação para a Ciência e a Tecnologia (the Portuguese Foundation for Science and Technology (FCT)) through Projects UID/CTM/50025/2013, PTDC/EME- MFE/113988/2009 and EXPL/CTM-POL/1299/2013. M. Rebelo acknowledge financial funding by the Portuguese Foundation for Science and Technology through the project PEstOE/MAT/UI0297/2013 (Centro de Matemática e Aplicacões

Radiocarbon and blue optically stimulated luminescence chronologies of the Oitavos consolidated dune (Western Portugal)

The dune of Oitavos, the underlying paleosol, and Helix sp. gastropod shells found within the paleosol were dated using a combination of radiocarbon and blue optically stimulated luminescence (OSL). The organic component of the paleosol produced a significantly older age (~20,000 cal BP) than the OSL age measurement (~15,000 yr), while 14C age measurements on the inorganic component and the gastropods produced ages of ~35,000 yr and ~34,000 yr, respectively. Rare-earth element analyses provide evidence that the gastropods incorporate geological carbonate, making them an unreliable indicator of the age of the paleosol. We propose that the 14C age of the small organic component of the paleosol is also likely to be unreliable due to incorporation of residual material. The OSL age measurement of the upper paleosol (~15,000 yr) is consistent with the age for the base of the dune (~14,500 yr). The younger OSL age for the top of the dune (~12,000 yr) suggests that it was built up by at least 2 sand pulses or that there was a remobilization of material at the top during its evolution, prior to consolidation

Influenza A(H1N1)pdm09 Resistance and Cross-Decreased Susceptibility to Oseltamivir and Zanamivir Antiviral Drugs

Neuraminidase inhibitors (NAIs) oseltamivir and zanamivir are currently the only effective antiviral drugs available worldwide for the management of influenza. The potential development of resistance is continually threatening their use, rationalizing and highlighting the need for a close and sustained evaluation of virus susceptibility. This study aimed to analyze and characterize the phenotypic and genotypic NAIs susceptibility profiles of A(H1N1)pdm09 viruses circulating in Portugal from 2009 to 2010/2011. A total of 144 cases of A(H1N1)pdm09 virus infection from community and hospitalized patients were studied, including three suspected cases of clinical resistance to oseltamivir. Oseltamivir resistance was confirmed for two of the suspected cases. Neuraminidase (NA) H275Y resistant marker was found in viruses from both cases but for one it was only present in 26.2% of virus population, raising questions about the minimal percentage of resistant virus that should be considered relevant. Cross-decreased susceptibility to oseltamivir and zanamivir (2-4 IC50 fold-change) was detected on viruses from two potentially linked community patients from 2009. Both viruses harbored the NA I223V mutation. NA Y155H mutation was found in 18 statistical non-outlier viruses from 2009, having no impact on virus susceptibility. The mutations at NA N369K and V241I may have contributed to the significantly higher baseline IC50 value obtained to oseltamivir for 2010/2011 viruses, compared to viruses from the pandemic period. These results may contribute to a better understanding of the relationship between phenotype and genotype, which is currently challenging, and to the global assessment of A(H1N1)pdm09 virus susceptibility profile and baseline level to NAIs

Vibration measurements on small to medium single-span railway bridges

Due to the need for increasing train speeds several existing small to medium span bridges in the track Linz-Wels (Austria) were re-evaluated. In a preliminary numerical calculation, considering conservative values for the dynamic parameters, very high vertical accelerations were computed for some of those structures. An experimental program was thus carried out in order to get a better estimation for the dynamic behaviour of the bridges, concerning mainly the first vertical eigenfrequency and the corresponding viscous damping. The paper reports on the results of this experimental investigation and identifies some areas where further research is necessary

A Genetic Algorithm solver for pest management control in Island systems

Island conservation management is a truly multidisciplinary problem that requires considerable knowledge of the characteristics of the ecosystem, species and their interactions. Nevertheless, this can be translated into an optimisation problem. Essentially, within a limited budget, a manager needs to select the conservation actions according to expected payoffs (in terms of protecting or restoring desired species) versus cost (the amount of resources/money) required for the actions. This paper presents the problem in terms of a knapsack formulation and develops optimisation techniques to solve it. From this, decision-support software is being developed, tailored to meet the needs of pest control on islands for conservation managers. The solver uses a Genetic Algorithm and incorporates a simplified model of the problem. The solver derives strategies that reduce the number of threats, allowing the preservation of desired species. However, the problem model needs further refinement to derive truly realistic options for conservation managers

D0−Dˉ0D^0 - \bar D^0 Mixing in the Presence of Isosinglet Quarks

We analyse $\Delta C=2$ transitions in the framework of a minimal extension of the Standard Model where either a $Q=2/3$ or a $Q=-1/3$ isosinglet quark is added to the standard quark spectrum. In the case of a $Q=2/3$ isosinglet quark, it is shown that there is a significant region of parameter space where $D^0 - \bar D^0$ mixing is sufficiently enhanced to be observed at the next round of experiments. On the contrary, in the case of a $Q=-1/3$ isosinglet quark, it is pointed out that obtaining a substancial enhancement of $D^0 - \bar D^0$ mixing, while complying with the experimental constraints on rare kaon decays, requires a contrived choice of parameters.Comment: 10 pages plus four figures. The figures are not included but are available upon reques

Aquaculture of the clam (Tapes decussatus) on a closed system.

43rd European Marine Biology Symposium. Ponta Delgada, Açores, 8-12 de Setembro de 2008