The nuisance due to the noise of automobile traffic: An investigation in the neighborhoods of freeways

An inquiry was held among 400 people living near freeways in an attempt to determine the characteristics of traffic noise nuisance. A nuisance index was compiled, based on the answers to a questionnaire. Nuisance expressed in these terms was then compared with the noise level measured on the most exposed side of each building. Correlation between the nuisance indexes and the average noise levels is quite good for dwellings with facades parallel to the freeway. At equal noise levels on the most exposed side, the nuisance given for these latter dwellings is lower than for others

Supporting health education policies: translation, cross-cultural adaptation and validation of a health literacy instrument, in French

Background: Oral health is a fundamental human right and is inseparable and indivisible from overall health and well-being. Oral Health Literacy (OHL) has been proved to be fundamental to promoting oral health and reducing oral health inequalities. To our knowledge, no OHL instrument to evaluate OHL level is currently validated in French language despite the fact it is the fifth most widely spoken languages on the planet. The Oral health literacy Instrument (OHLI) appears to be the most interesting OHL instrument to adapt into French because it is already available in English, Spanish, Russian, Malaysian, and it contains both reading comprehension and numeracy sections. Its psychometric properties have been rated as adequate. Objective: The aim of this study was to translate and adapt cross-culturally the OHLI into French, to evaluate its psychometric properties and to compare its results to oral health knowledge. Method: This study followed and applied well-established processes of translation, cross-cultural adaptation and validation, based on the recommendations of the World Health Organization guidelines and on the Consensus-Based Standards for the Selection of Health Measurement Instruments (COSMIN) study design checklist for patient-reported outcomes. Two psychometric assessments were planned, the comparison of OHLI-F scores according to education level and frequency of dental visits, and the test-retest reliability of the OHLI-F. Results: A total of 284 participants answered the OHLI-F. The OHLI-F scores were significantly different between participants with different levels of education and frequency of dental visits (p < 0.001). Participants with an education level lower than the baccalaureate, and those who never visit the dentist or only in case of pain, had significantly lower OHLI-F scores. Internal consistency was excellent (Cronbach's alpha = 0.881-0.914). Test-retest reliability was very high (intraclass correlation = 0.985 to 0.996). Conclusion: The OHLI-F has demonstrated adequate psychometric properties and can therefore be used to measure oral health literacy in French-speaking populations

Percepção sonora e conforto acústico em espaços urbanos do município de Belo Horizonte, MG

Resumo O presente artigo tem como objetivo apresentar e analisar as respostas dos usuários de espaços urbanos abertos com relação à percepção do volume sonoro e à avaliação de conforto acústico, com base em dados coletados em campo durante o ano de 2013, em duas praças do município de Belo Horizonte, MG. Durante os levantamentos, dados acústicos foram medidos simultaneamente à aplicação de questionários, utilizados para coleta de variáveis subjetivas e individuais. O LAeq,T foi o índice utilizado para caracterização dos ambientes sonoros. Os resultados demonstram que, sob as mesmas condições acústicas, tanto no que diz respeito à percepção do volume sonoro quanto à avaliação de conforto acústico, os indivíduos tendem a ser mais tolerantes na praça que possui a melhor ambiência e as melhores condições de conforto térmico. As faixas de percepção do volume sonoro definidas neste estudo foram: Baixo, LAeq < 35 dB(A); Normal, 36 < LAeq < 67 dB(A); Alto, LAeq > 68 dB(A). Com relação à avaliação do conforto acústico, as faixas definidas foram: Confortável, LAeq < 67 dB(A); e Desconfortável, LAeq > 68 dB(A). Espera-se que esses resultados contribuam para um maior entendimento das questões relativas ao conforto acústico urbano

COVID-19 infection in adult patients with hematological malignancies: a European Hematology Association Survey (EPICOVIDEHA)

Background: Patients with hematological malignancies (HM) are at high risk of mortality from SARS-CoV-2 disease 2019 (COVID-19). A better understanding of risk factors for adverse outcomes may improve clinical management in these patients. We therefore studied baseline characteristics of HM patients developing COVID-19 and analyzed predictors of mortality. Methods: The survey was supported by the Scientific Working Group Infection in Hematology of the European Hematology Association (EHA). Eligible for the analysis were adult patients with HM and laboratory-confirmed COVID-19 observed between March and December 2020. Results: The study sample includes 3801 cases, represented by lymphoproliferative (mainly non-Hodgkin lymphoma n = 1084, myeloma n = 684 and chronic lymphoid leukemia n = 474) and myeloproliferative malignancies (mainly acute myeloid leukemia n = 497 and myelodysplastic syndromes n = 279). Severe/critical COVID-19 was observed in 63.8% of patients (n = 2425). Overall, 2778 (73.1%) of the patients were hospitalized, 689 (18.1%) of whom were admitted to intensive care units (ICUs). Overall, 1185 patients (31.2%) died. The primary cause of death was COVID-19 in 688 patients (58.1%), HM in 173 patients (14.6%), and a combination of both COVID-19 and progressing HM in 155 patients (13.1%). Highest mortality was observed in acute myeloid leukemia (199/497, 40%) and myelodysplastic syndromes (118/279, 42.3%). The mortality rate significantly decreased between the first COVID-19 wave (March–May 2020) and the second wave (October–December 2020) (581/1427, 40.7% vs. 439/1773, 24.8%, p value < 0.0001). In the multivariable analysis, age, active malignancy, chronic cardiac disease, liver disease, renal impairment, smoking history, and ICU stay correlated with mortality. Acute myeloid leukemia was a higher mortality risk than lymphoproliferative diseases. Conclusions: This survey confirms that COVID-19 patients with HM are at high risk of lethal complications. However, improved COVID-19 prevention has reduced mortality despite an increase in the number of reported cases.EPICOVIDEHA has received funds from Optics COMMITTM (COVID-19 Unmet Medical Needs and Associated Research Extension) COVID-19 RFP program by GILEAD Science, United States (Project 2020-8223)

Decoding the historical tale: COVID-19 impact on haematological malignancy patients-EPICOVIDEHA insights from 2020 to 2022

The COVID-19 pandemic heightened risks for individuals with hematological malignancies due to compromised immune systems, leading to more severe outcomes and increased mortality. While interventions like vaccines, targeted antivirals, and monoclonal antibodies have been effective for the general population, their benefits for these patients may not be as pronounced.Peer reviewe