Telemedicine of family-based treatment for adolescent anorexia nervosa: A protocol of a treatment development study.

BackgroundFamily-based treatment is an efficacious treatment available for adolescents with anorexia nervosa. Yet the implementation of this treatment, at least in the United States, is challenging due to a limited number of trained family-based treatment therapists and the concentration of these therapists in a limited number of urban centers. The use of telemedicine in the delivery of family-based treatment can increase access to this therapy for this patient population.Methods/designThis two-year treatment development study (December 2013-November 2015) follows a two-wave iterative case series design. The study is ongoing and addresses the treatment needs of families in remote, rural, or underrepresented parts of the United States by delivering family-based treatment via telemedicine (video chat). The first six months of the study was dedicated to selecting a cloud-based secure telemedicine portal for use with participants. Recruitment for the first of two consecutive case series (N = 5) began during month seven. After these five patients completed treatment, a systematic review of treatment via feedback from participants and therapists related to the delivery of this model and use of technology was completed. A second wave of recruitment is underway (N = 5). At the end of both waves (N = 10), and after a second review of treatment, we should be able to establish the feasibility and acceptability of family-based treatment delivered via telemedicine for this patient population.DiscussionThis study is the first attempt to deliver family-based treatment for adolescents with anorexia nervosa via telemedicine. If delivering family-based treatment in this format is feasible, it will provide access to an evidence-based treatment for families heretofore unable to participate in specialist treatment for their child's eating disorder

The Kinematic Evolution of Strong MgII Absorbers

We consider the evolution of strong (W_r(2796) > 0.3A) MgII absorbers, most of which are closely related to luminous galaxies. Using 20 high resolution quasar spectra from the VLT/UVES public archive, we examine 33 strong MgII absorbers in the redshift range 0.3 < z < 2.5. We compare and supplement this sample with 23 strong MgII absorbers at 0.4 < z < 1.4 observed previously with HIRES/Keck. We find that neither equivalent width nor kinematic spread (the optical depth weighted second moment of velocity) of MgII2796 evolve. However, the kinematic spread is sensitive to the highest velocity component, and therefore not as sensitive to additional weak components at intermediate velocities relative to the profile center. The fraction of absorbing pixels within the full velocity range of the system does show a trend of decreasing with decreasing redshift. Most high redshift systems (14/20) exhibit absorption over the entire system velocity range, which differs from the result for low redshift systems (18/36) at the 95% level. This leads to a smaller number of separate subsystems for high redshift systems because weak absorping components tend to connect the stronger regions of absorption. We hypothesize that low redshift MgII profiles are more likely to represent well formed galaxies, many of which have kinematics consistent with a disk/halo structure. High redshift MgII profiles are more likely to show evidence of complex protogalactic structures, with multiple accretion or outflow events. Although these results are derived from measurements of gas kinematics, they are consistent with hierarchical galaxy formation evidenced by deep galaxy surveys.Comment: Accepted to the Astrophysical Journa

Stretching the limits in help-seeking research

This special section focuses on help seeking in a wide range of learning environments, from classrooms to online forums. Previous research has rather restrictively focused on the identification of personal characteristics that predict whether or not learners seek help under certain conditions. However, help-seeking research has begun to broaden these self-imposed limitations. The papers in this special section represent good examples of this development. Indeed, help seeking in the presented papers is explored through complementary theoretical lenses (e.g., linguistic, instructional), using a wide scope of methodologies (e.g., teacher reports, log files), and in a manner which embraces the support of innovative technologies (e.g., cognitive tutors, web-based environments)

Noise and vibration from building-mounted micro wind turbines Part 2: Results of measurements and analysis

Description To research the quantification of vibration from a micro turbine, and to develop a method of prediction of vibration and structure borne noise in a wide variety of installations in the UK. Objective The objectives of the study are as follows: 1) Develop a methodology to quantify the amount of source vibration from a building mounted micro wind turbine installation, and to predict the level of vibration and structure-borne noise impact within such buildings in the UK. 2) Test and validate the hypothesis on a statically robust sample size 3) Report the developed methodology in a form suitable for widespread adoption by industry and regulators, and report back on the suitability of the method on which to base policy decisions for a future inclusion for building mounted turbines in the GPDO

Contested waterscapes in the Greater Amboseli Ecosystem, Kenya: socio-hydrology for the benefit of conservationists, peasants, and pastoralists

We focus on the appropriation, conflicting uses and meanings of water in a semi-arid environment marked by resource spatiotemporal variability. The Amboseli ecosystem, inhabited by semi-nomadic Maasai pastoralists and many wildlife species of the East African savanna, has likewise long been a stage for enacting a multitude of top-down governmental and non-governmental conservation policies. Agriculture has also taken hold in the rangelands as a result of development initiatives, thereby contributing, along with complex interactions between numerous other social, political, economic, and ecological factors, to the sedentarization of Ilkisongo pastoralists whose livelihoods have thus recently diversified. In a context where rains are erratic and groundwater reserves are poorly known, water is often a limiting resource for forage, agriculture, and wildlife, so thus often contentious in numerous dimensions regarding access, social relations and in human–wildlife interactions. Through a collection of narratives collected in the field we examine the challenges raised by water scarcity and analyse the situation through a postcolonial, marxist, and postdevelopmental approach. The ethnographic survey involved long immersion periods among Maasai stakeholders, interviews with farmers, conservation NGOs and other institutional leaders, and participatory events were generated around role-playing games focused on water, land use and land tenure. By articulating political, economic, cultural and gender dimensions this multi-pronged methodology showcases socio-hydrology as a situated science. Our participatory approach gauges how current tension around water management can be addressed by integrating the local population, environmental managers and outsiders, with consequences for decision making at individual and collective level and for the ecosystem

The Poverty Crusher

The Poverty Crusher team built a human-powered rock breaking device for the women in Nepal who make $1.50 -$3 per day crushing rocks. A prototype jaw-type rock crusher was designed and built over a period of several months. However, the device was unable to break rocks due to excessive bending in the connection points of the frame and in the crushing faces. Improvements were suggested for the next prototype, which include increasing the second moment of inertia of the crushing faces, using a welded frame, and generally decreasing the cost and weight of the device

Tacotron: Towards End-to-End Speech Synthesis

A text-to-speech synthesis system typically consists of multiple stages, such as a text analysis frontend, an acoustic model and an audio synthesis module. Building these components often requires extensive domain expertise and may contain brittle design choices. In this paper, we present Tacotron, an end-to-end generative text-to-speech model that synthesizes speech directly from characters. Given pairs, the model can be trained completely from scratch with random initialization. We present several key techniques to make the sequence-to-sequence framework perform well for this challenging task. Tacotron achieves a 3.82 subjective 5-scale mean opinion score on US English, outperforming a production parametric system in terms of naturalness. In addition, since Tacotron generates speech at the frame level, it's substantially faster than sample-level autoregressive methods.Comment: Submitted to Interspeech 2017. v2 changed paper title to be consistent with our conference submission (no content change other than typo fixes

Data Quality Assessment of Ungated Flow Cytometry Data in High

Background: The recent development of semi-automated techniques for staining and analyzing flow cytometry samples has presented new challenges. Quality control and quality assessment are critical when developing new high throughput technologies and their associated information services. Our experience suggests that significant bottlenecks remain in the development of high throughput flow cytometry methods for data analysis and display. Especially, data quality control and quality assessment are crucial steps in processing and analyzing high throughput flow cytometry data. Methods: We propose a variety of graphical exploratory data analytic tools for exploring ungated flow cytometry data. We have implemented a number of specialized functions and methods in the Bioconductor package rflowcyt. We demonstrate the use of these approaches by investigating two independent sets of high throughput flow cytometry data. Results: We found that graphical representations can reveal substantial non-biological differences in samples. Empirical Cumulative Distribution Function and summary scatterplots were especially useful in the rapid identification of problems not identified by manual review. Conclusions: Graphical exploratory data analytic tools are quick and useful means of assessing data quality. We propose that the described visualizations should be used as quality assessment tools and where possible, be used for quality control

Long Duration Life Test of Propylene Glycol Water Based Thermal Fluid Within Thermal Control Loop

Evaluations of thermal properties and resistance to microbial growth concluded that 50% Propylene Glycol (PG)-based fluid and 50% de-ionized water mixture was desirable for use as a fluid within a vehicle s thermal control loop. However, previous testing with a commercial mixture of PG and water containing phosphate corrosion inhibitors resulted in corrosion of aluminum within the test system and instability of the test fluid. This paper describes a follow-on long duration testing and analysis of 50% Propylene Glycol (PG)-based fluid and 50% de-ionized water mixture with inorganic corrosion inhibitors used in place of phosphates. The test evaluates the long-term fluid stability and resistance to microbial and chemical change