Factors associated with failed treatment : an analysis of 121,744 women embarking on their first IVF cycles

Peer reviewedPublisher PD

Bipartite entangled stabilizer mutually unbiased bases as maximum cliques of Cayley graphs

We examine the existence and structure of particular sets of mutually unbiased bases (MUBs) in bipartite qudit systems. In contrast to well-known power-of-prime MUB constructions, we restrict ourselves to using maximally entangled stabilizer states as MUB vectors. Consequently, these bipartite entangled stabilizer MUBs (BES MUBs) provide no local information, but are sufficient and minimal for decomposing a wide variety of interesting operators including (mixtures of) Jamiolkowski states, entanglement witnesses and more. The problem of finding such BES MUBs can be mapped, in a natural way, to that of finding maximum cliques in a family of Cayley graphs. Some relationships with known power-of-prime MUB constructions are discussed, and observables for BES MUBs are given explicitly in terms of Pauli operators.Comment: 8 pages, 1 figur

Implicit homophobic argument structure: equal-marriage discourse in The Moral Maze

This article analyses the linguistic and discursive elements which contribute to the production of implicit homophobia. Explicit homophobia has been well documented and strategies for countering discriminatory language have been developed (Baker, 2014; Leap, 2012). However, our interest here is in documenting implicit homophobia, where homophobic beliefs are only hinted at, are disassociated from the speaker, or are embedded within discursive and argument structures. We decided to analyse the debate in the media around the introduction of equal or same­-sex marriage legislation in the UK. We focused our analysis on a series of radio programmes on BBC Radio 4, The Moral Maze, (2011­12) where the issue of same­-sex marriage was debated with a team of panelists and invited guests from a range of different organisations. Different perspectives on same sex marriage were discussed, in a seemingly objective and dispassionate way, where the interactants distanced themselves from homophobic beliefs and yet, implicitly subscribed to implicit homophobia. We used an analysis drawing on argumentation structure (Fairclough and Fairclough, 2012) and through focusing on stance, recontextualisation, imaginaries, and metaphor, we developed an analysis which made the way that implicit homophobia works more visible. In this way, we hope to foreground implicit homophobia, and develop a linguistic and discursive `toolkit’ which will enable it to be challenged and countered

Modelling the unfolding pathway of biomolecules: theoretical approach and experimental prospect

We analyse the unfolding pathway of biomolecules comprising several independent modules in pulling experiments. In a recently proposed model, a critical velocity $v_{c}$ has been predicted, such that for pulling speeds $v>v_{c}$ it is the module at the pulled end that opens first, whereas for $v<v_{c}$ it is the weakest. Here, we introduce a variant of the model that is closer to the experimental setup, and discuss the robustness of the emergence of the critical velocity and of its dependence on the model parameters. We also propose a possible experiment to test the theoretical predictions of the model, which seems feasible with state-of-art molecular engineering techniques.Comment: Accepted contribution for the Springer Book "Coupled Mathematical Models for Physical and Biological Nanoscale Systems and Their Applications" (proceedings of the BIRS CMM16 Workshop held in Banff, Canada, August 2016), 16 pages, 6 figure

Opposition as victimhood in newspaper debates about same-sex marriage

In this paper, we take a queer linguistics approach to the analysis of data from British newspaper articles which discuss the introduction of same-sex marriage. Drawing on methods from CDA and corpus linguistics, we focus on the construction of agency in relation to the government extending marriage to same-sex couples, and those resisting this. We show that opponents to same-sex marriage are represented and represent themselves as victims whose moral values, traditions, and civil liberties are being threatened by the state. Specifically, we argue that victimhood is invoked in a way that both enables and permits discourses of implicit homophobia

Fundamental performance similarities between individual pitch control strategies for wind turbines.

The use of blade individual pitch control (IPC) offers a means of reducing the harmful turbine structural loads that arise from the uneven and unsteady forcing from the oncoming wind. In recent years two different and competing IPC techniques have emerged that are characterised by the specific loads that they are primarily designed to attenuate. In the first instance, methodologies such as single-blade control and Clarke Transform-based control have been developed to reduce the unsteady loads on the rotating blades, whilst tilt-yaw control and its many variants instead target load reductions in the non rotating turbine structures, such as the tower and main bearing. Given the seeming disparities between these controllers, the aim of this paper is to show the fundamental performance similarities that exist between them and hence unify research in this area. Specifically, we show that single-blade controllers are equivalent to a particular class of tilt-yaw controller, which itself is equivalent to Clarke~Transform-based control. This means that three architecturally dissimilar IPC controllers exist that yield exactly the same performance in terms of load reductions on fixed and rotating turbine structures. We further demonstrate this outcome by presenting results obtained from high-fidelity closed-loop turbine simulations

Reliability and validity of three questionnaires measuring context-specific sedentary behaviour and associated correlates in adolescents, adults and older adults

BACKGROUND: Reliable and valid measures of total sedentary time, context-specific sedentary behaviour (SB) and its potential correlates are useful for the development of future interventions. The purpose was to examine test-retest reliability and criterion validity of three newly developed questionnaires on total sedentary time, context-specific SB and its potential correlates in adolescents, adults and older adults. METHODS: Reliability and validity was tested in six different samples of Flemish (Belgium) residents. For the reliability study, 20 adolescents, 22 adults and 20 older adults filled out the age-specific SB questionnaire twice. Test-retest reliability was analysed using Kappa coefficients, Intraclass Correlation Coefficients and/or percentage agreement, separately for the three age groups. For the validity study, data were retrieved from 62 adolescents, 33 adults and 33 older adults, with activPAL as criterion measure. Spearman correlations and Bland-Altman plots (or non-parametric approach) were used to analyse criterion validity, separately for the three age groups and for weekday, weekend day and average day. RESULTS: The test-retest reliability for self-reported total sedentary time indicated following values: ICC = 0.37-0.67 in adolescents; ICC = 0.73-0.77 in adults; ICC = 0.68-0.80 in older adults. Item-specific reliability results (e.g. context-specific SB and its potential correlates) showed good-to-excellent reliability in 67.94%, 68.90% and 66.38% of the items in adolescents, adults and older adults respectively. All items belonging to sedentary-related equipment and simultaneous SB showed good reliability. The sections of the questionnaire with lowest reliability were: context-specific SB (adolescents), potential correlates of computer use (adults) and potential correlates of motorized transport (older adults). Spearman correlations between self-reported total sedentary time and the activPAL were different for each age group: rho = 0.02-0.42 (adolescents), rho = 0.06-0.52 (adults), rho = 0.38-0.50 (older adults). Participants over-reported total sedentary time (except for weekend day in older adults) compared to the activPAL, for weekday, weekend day and average day respectively by +57.05%, +46.29%, +53.34% in adolescents; +40.40%, +19.15%, +32.89% in adults; +10.10%, -6.24%, +4.11% in older adults. CONCLUSIONS: The questionnaires showed acceptable test-retest reliability and criterion validity. However, over-reporting of total SB was noticeable in adolescents and adults. Nevertheless, these questionnaires will be useful in getting context-specific information on SB

Case studies and comparative analysis of energy efficiency in wheat production in different climatic conditions of Europe

The paper presents results concerning energy efficiency of wheat production considered in the context of specific energy input variation in different climatic conditions of Europe as well as case studies on implementation of selected energy saving measures in practice. It was shown that the highest wheat yield (6.7-8.7 t·ha-1) at the lowest specific energy input (2.08-2.56 GJ·t-1) is unique for temperate climate conditions. The yield in continental and Mediter-ranean climatic conditions is on average lower by 1.3 t·ha-1 and 2.7 t·ha-1 and energy effi-ciency lower by 14% and 38%, respectively. The case studies have shown that the energy saving activities in wheat production may be universal for the climatic zones or specific for a given geographical location. It was stated that trade-offs between energy, economic and en-vironmental effects, which are associated with implementation of a given energy saving measure or a set of measures to a great extent depend on the current energy efficiency sta-tus of the farm and opportunity for investment, which varies substantially across Europe

Survival of dental implants in patients with oral cancer treated by surgery and radiotherapy: a retrospective study

BACKGROUND: The aim of this retrospective study was to evaluate the survival of dental implants placed after ablative surgery, in patients affected by oral cancer treated with or without radiotherapy. METHODS: We collected data for 34 subjects (22 females, 12 males; mean age: 51 ± 19) with malignant oral tumors who had been treated with ablative surgery and received dental implant rehabilitation between 2007 and 2012. Postoperative radiation therapy (less than 50 Gy) was delivered before implant placement in 12 patients. A total of 144 titanium implants were placed, at a minimum interval of 12 months, in irradiated and non-irradiated residual bone. RESULTS: Implant loss was dependent on the position and location of the implants (P = 0.05-0.1). Moreover, implant survival was dependent on whether the patient had received radiotherapy. This result was highly statistically significant (P < 0.01). Whether the implant was loaded is another highly significant (P < 0.01) factor determinin

Are bisphosphonates effective in the treatment of osteoarthritis pain? A meta-analysis and systematic review.

Osteoarthritis (OA) is the most common form of arthritis worldwide. Pain and reduced function are the main symptoms in this prevalent disease. There are currently no treatments for OA that modify disease progression; therefore analgesic drugs and joint replacement for larger joints are the standard of care. In light of several recent studies reporting the use of bisphosphonates for OA treatment, our work aimed to evaluate published literature to assess the effectiveness of bisphosphonates in OA treatment