Flavonol glycosides from Asperula arvensis L.

From the aerial parts of Asperula arvensis L. 9 known flavonol glycosides, namely quercetin (1), isoquercitrin [= quercetin 3-O-beta-glucopyranoside] (2), hyperin [= quercetin 3-O-beta-galactopyranoside] (3), quercetin 7-O-beta-galactopyranoside (4), quercetin 4'-O-beta-galactopyranoside (5), isorhamnetin 3-O-beta-galactopyranoside (6), isorhamnetin 5-0-beta-galactopyranoside (7), dihydrokaempferol 7-4'-dimethylether 3-O-beta-glucopyranoside (8) and isorhamnetin 3-O-alpha-rhamnopyranosyl (1''' -> 6'')-beta-glucopyranosid (9), were isolated. The structures of the compounds were elucidated by high field 1D and 2D NMR and ESI-MS spectroscopies

Sedative, anticonvulsant and behaviour modifying effects of Centranthus longiflorus ssp longiflorus: a study of comparison to diazepam

The aqueous extract of Centranthus longiflorus ssp. longiflorus (CLE) was investigated for sedative, anticonvulsant and behaviour modifying activity using thiopental sleeping, caffeine induced convulsion and forced swimming depression tests. When the effects of the aqueous extract of CLE (100 mg/kg) was compared to diazepam, it showed similar sedative and anticonvulsant effects to those produced by diazepam (5 mg/kg)

Effects of Rumex patientia root extract on indomethacine and ethanol induced gastric damage in rats

The effects of an aqueous root extract from Rumex patientia (D-1) compared to COX-2 selective inhibitors on indomethacine and ethanol induced stomach ulcers were investigated. Adult male Wistar albino rats, weighing between 185-200 g were used. It was determined that D-1 does not show its gastroprotective activity via a COX enzyme in indomethacine induced ulcers. Antioxidant effects protect the gastrointestinal system. The effect of D-1 in ethanol induced ulcers may also be due to its antioxidant effect

The effects of Rumex patientia extract on rat liver and erythrocyte antioxidant enzyme system

The aqueous extract from the roots of Rumex patientia L. (Polygonaceae) (D-1) was investigated for its effects on rat liver and erythrocyte antioxidant enzyme systems and lipid peroxidation. Measurements of the GSH-Px, SOD and CAT activities, and MDA levels of liver and erythrocytes in D-1 administered animals showed that there was an increase in GSH-Px and SOD activities when compared to that of controls. No significant decrease was observed in catalase activity and no changes in malondialdehyde levels were observed