10,754 research outputs found

    Characterizing the development of sectoral Gross Domestic Product composition

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    We consider the sectoral composition of a country's GDP, i.e. the partitioning into agrarian, industrial, and service sectors. Exploring a simple system of differential equations we characterize the transfer of GDP shares between the sectors in the course of economic development. The model fits for the majority of countries providing 4 country-specific parameters. Relating the agrarian with the industrial sector, a data collapse over all countries and all years supports the applicability of our approach. Depending on the parameter ranges, country development exhibits different transfer properties. Most countries follow 3 of 8 characteristic paths. The types are not random but show distinct geographic and development patterns.Comment: 7 pages, 4 figure

    Interoperable Registers and Registries in the EU: Perspectives from INSPIRE

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    INSPIRE is a EU-wide data and service infrastructure for the cross-border sharing of environmental data and for their use in support to policy making. This paper introduces the context, requirements and issues for registers and registries in INSPIRE, including persistent identifiers, versioning, multi-linguality, extensibility, linking and alignment with existing registers and cross-sector interoperability and re-use. In our presentation, besides highlighting open issues relevant not only in the scope of INSPIRE, we will report the results of an INSPIRE workshop on registers/registries taking place on 22-23 January 2014.JRC.H.6-Digital Earth and Reference Dat

    Field theory on kappa-spacetime

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    A general formalism is developed that allows the construction of field theory on quantum spaces which are deformations of ordinary spacetime. The symmetry group of spacetime is replaced by a quantum group. This formalism is demonstrated for the kappa-deformed Poincare algebra and its quantum space. The algebraic setting is mapped to the algebra of functions of commuting variables with a suitable star-product. Fields are elements of this function algebra. As an example, the Klein-Gordon equation is defined and derived from an action.Comment: 7 pages, talk given by L. Jonke at the XIII International Colloquium on Integrable Systems and Quantum Groups, June 2004, Pragu

    Once-daily saquinavir (SAQ)/ritonavir (RTV) (2000/100 mg) with abacavir/lamivudine (600/300 mg) or tenofovir/emtricitabine (245/300 mg) in naïve patients

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    Poster presentation: Background In the past years, once-daily (QD) dosing of antiretroviral combination therapy has become an increasingly available treatment option for HIV-1+ patients. Methods Open label study in which HIV-1+ patients treated with SAQ/RTV (1000/100 mg BID) and two NRTIs with HIV-RNA-PCR < 50 copies/ml were switched to SAQ/RTV(2000/100 mg QD) with unchanged NRTI-backbone. CD4-cells, HIV-RNA-PCR, SAQ and RTV drug-levels and metabolic parameters were compared. Summary of results 17 patients (15 male, 42 years), median CD4 456 ± 139/micro l were included so far. The median follow-up time is 4 months. The HIV-RNA-PCR remained <50 copies/ml for all patients. Fasting metabolic parameters remained unchanged. The SAQ AUC 0–12 h were significantly higher when given QD vs. BID (median 29,400 vs. 18,500 ng*h/ml; p = 0.009), whereas the Cmin, Cmax and AUC was lower for RTV when given QD vs. BID (7,400 vs. 11,700 ng*h/ml; p = 0.02). Conclusion In this ongoing study SAQ/RTV (2000/100 mg QD) was well tolerated and demonstrated higher SAQ and lower RTV drug levels as compared to the BID dosing schedule. (Table 1 and Figure 1.
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