872 research outputs found
Development of a rotating gravity gradiometer for earth orbit applications (AAFE)
Some preliminary mission studies are described along with the design, fabrication, and test of a breadboard model of an earth orbital, rotating gravity gradiometer with a design goal of 10 to the minus 11th power/sec sq (0.01 EU) in a 35-sec integration time. The proposed mission uses a Scout vehicle to launch one (or two orthogonally oriented) spin-stabilized satellites into a 330-km circular polar orbit some 20 days before an equinox. During the short orbital lifetime, the experiment would obtain two complete maps of the gravity gradient field with a resolution approaching 270 km (degree 75). The breadboard model of the gradiometer demonstrated a combined thermal and electronic noise threshold of 0.015 EU per data channel. The design changes needed to reduce the noise to less than 0.01 EU were identified. Variations of the sensor output signal with temperature were experimentally determined and a suitable method of temperature compensation was developed and tested. Other possible error sources, such as sensor interaction with satellite dynamics and magnetic fields, were studied analytically and shown to be small
Partial reconstitution of DNA large loop repair with purified proteins from Saccharomyces cerevisiae
How might the gender roles affect the implementation of a new water-saving technique for Colombian rice production? : Report of gender dimensions in Colombian rice production
Globally, rice cultivation is responsible for 10% of greenhouse gas emissions released by agricultural activities. To sustainably reduce the contribution of rice to greenhouse gas (GHG) emissions, it is important to pursue management and technological options that reduce emissions and improve farmer productivity, adaptation and resilience to climate change impacts. Alternate wetting and drying (AWD) is a water-saving technique that helps farmers adapt to less water availability. It reduces the amount of in-field gas emissions associated with rice production, and it may increase and/or maintain rice productivity levels. The International Center for Tropical Agriculture (CIAT) and partners are conducting several studies to evaluate the feasibility of implementing this technology in Colombia, a country that has committed to reducing economy-wide GHG emissions by 20% under the 2015 Paris Agreement and implementing adaptation plans by 2030. The sustainable implementation of AWD requires an understanding of the economic, climatic, political, agronomic and social considerations within which farmers operate. The literature shows how gender roles can influence the adoption of a technology or be affected by the introduction of a new technology. A baseline study was designed to answer the following questions: how might gender impact the adoption of AWD in Colombia? And how will the adoption of AWD affect the gender division of labor? A household survey with sex-disaggregated information in 609 households in five departments was conducted. The results suggest that women own rice assets and make decisions about production but are not recognized as rice producers. They do not receive agricultural information and do not have group membership in the same proportion as men do. Furthermore, households in which women participate as producers are more likely to have noneconomic incentives and water availability (i.e. no problems with water scarcity) to implement AWD. Women participate in manual weed control as hired labor and men participate more in irrigation, and both activities can be affected by the implementation of AWD. For AWD to be widely implemented in Colombia, it is important to target women as well as men and create awareness of the possible social effects of the technology in gendered labor activities, and therefore in the lives of both women and men
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Impact of Irrigation Strategies on Tomato Root Distribution and Rhizosphere Processes in an Organic System.
Root exploitation of soil heterogeneity and microbially mediated rhizosphere nutrient transformations play critical roles in plant resource uptake. However, how these processes change under water-saving irrigation technologies remains unclear, especially for organic systems where crops rely on soil ecological processes for plant nutrition and productivity. We conducted a field experiment and examined how water-saving subsurface drip irrigation (SDI) and concentrated organic fertilizer application altered root traits and rhizosphere processes compared to traditional furrow irrigation (FI) in an organic tomato system. We measured root distribution and morphology, the activities of C-, N-, and P-cycling enzymes in the rhizosphere, the abundance of rhizosphere microbial N-cycling genes, and root mycorrhizal colonization rate under two irrigation strategies. Tomato plants produced shorter and finer root systems with higher densities of roots around the drip line, lower activities of soil C-degrading enzymes, and shifts in the abundance of microbial N-cycling genes and mycorrhizal colonization rates in the rhizosphere of SDI plants compared to FI. SDI led to 66.4% higher irrigation water productivity than FI, but it also led to excessive vegetative growth and 28.3% lower tomato yield than FI. Our results suggest that roots and root-microbe interactions have a high potential for coordinated adaptation to water and nutrient spatial patterns to facilitate resource uptake under SDI. However, mismatches between plant needs and resource availability remain, highlighting the importance of assessing temporal dynamics of root-soil-microbe interactions to maximize their resource-mining potential for innovative irrigation systems
Minimal breast milk transfer of rituximab, a monoclonal antibody used in neurological conditions.
ObjectiveTo determine the transfer of rituximab, an anti-CD20 monoclonal antibody widely used for neurologic conditions, into mature breast milk.MethodsBreast milk samples were collected from 9 women with MS who received rituximab 500 or 1,000 mg intravenous once or twice while breastfeeding from November 2017 to April 2019. Serial breast milk samples were collected before infusion and at 8 hours, 24 hours, 7 days, and 18-21 days after rituximab infusion in 4 patients. Five additional patients provided 1-2 samples at various times after rituximab infusion.ResultsThe median average rituximab concentration in mature breast milk was low at 0.063 μg/mL (range 0.046-0.097) in the 4 patients with serial breast milk collection, with an estimated median absolute infant dose of 0.0094 mg/kg/d and a relative infant dose (RID) of 0.08% (range 0.06%-0.10%). Most patients had a maximum concentration at 1-7 days after infusion. The maximum concentration occurred in a woman with a single breast milk sample and was 0.29 μg/mL at 11 days postinfusion, which corresponds with an estimated RID of 0.33%. Rituximab concentration in milk was virtually undetectable by 90 days postinfusion.ConclusionsWe determined minimal transfer of rituximab into mature breast milk. The RID for rituximab was less than 0.4% and well below theoretically acceptable levels of less than 10%. Low oral bioavailability would probably also limit the absorption of rituximab by the newborn. In women with serious autoimmune neurologic conditions, monoclonal antibody therapy may afford an acceptable benefit to risk ratio, supporting both maternal treatment and breastfeeding
Cervical dystonia incidence and diagnostic delay in a multiethnic population.
BackgroundCurrent cervical dystonia (CD) incidence estimates are based on small numbers in relatively ethnically homogenous populations. The frequency and consequences of delayed CD diagnosis is poorly characterized.ObjectivesTo determine CD incidence and characterize CD diagnostic delay within a large, multiethnic integrated health maintenance organization.MethodsWe identified incident CD cases using electronic medical records and multistage screening of more than 3 million Kaiser Permanente Northern California members from January 1, 2003, to December 31, 2007. A final diagnosis was made by movement disorders specialist consensus. Diagnostic delay was measured by questionnaire and health utilization data. Incidence rates were estimated assuming a Poisson distribution of cases and directly standardized to the 2000 U.S. census. Multivariate logistic regression models were employed to assess diagnoses and behaviors preceding CD compared with matched controls, adjusting for age, sex, and membership duration.ResultsCD incidence was 1.18/100,000 person-years (95% confidence interval [CI], 0.35-2.0; women, 1.81; men, 0.52) based on 200 cases over 15.4 million person-years. Incidence increased with age. Half of the CD patients interviewed reported diagnostic delay. Diagnoses more common in CD patients before the index date included essential tremor (odds ratio [OR] 68.1; 95% CI, 28.2-164.5), cervical disc disease (OR 3.83; 95% CI, 2.8-5.2), neck sprain/strain (OR 2.77; 95% CI, 1.99-3.62), anxiety (OR 2.24; 95% CI, 1.63-3.11) and depression (OR 1.94; 95% CI, 1.4-2.68).ConclusionsCD incidence is greater in women and increases with age. Diagnostic delay is common and associated with adverse effects. © 2019 International Parkinson and Movement Disorder Society
ROSIsat
As the cost of sending satellites into space continues to drive down, the use of CubeSats for orbital missions continues to rise. Even though these satellites are smaller than traditional satellites, they still provide the ability to take on important science-based missions at a fraction of the cost. The Radiation Orbital Shielding Investigation satellite (ROSIsat) previously known as Project Hermes, will be the first fully student-built satellite for Embry-Riddle’s Daytona Beach campus. The main research mission of ROSIsat consists of shielding onboard memory modules from space radiation using various materials. These materials include simulated Martian and Lunar regolith. To send a student-built CubeSat to space, the ROSIsat team is designing and integrating the majority of the satellite’s components in-house. These in-house components include the CubeSat’s chassis, on-board computer, magnetorquer and payload electronics.. ROSIsat will provide students with educational, technical, scientific, and legal knowledge that can be applied in their respective futures
Radiation Orbital Shielding Investigation Satellite
In the last twenty years, CubeSats and similar small satellites have become increasingly popular, offering a cost-effective way to conduct important scientific activities in low Earth orbit when compared to traditional satellites. These compact satellites serve various purposes, including scientific research, education, technology demonstrations, and commercial applications like communication networks. The Radiation Orbital Shielding Investigation Satellite (ROSIsat) is a 1U CubeSat project specifically designed to study the effectiveness of different materials in shielding against radiation in space. To aid in the development of ROSIsat, some CubeSat components will be produced on-site, while more complex parts will be sourced externally. The main goal of ROSIsat is to carry out experiments related to radiation shielding, which is crucial for aerospace missions. The team plans to test nine different materials, including simulants of lunar and Martian regolith, to improve spacecraft protection during future missions to these celestial bodies. ROSIsat\u27s launch will be facilitated through a rideshare service such as Spaceflight, Nanoracks, or NASA\u27s CubeSat Launch Initiative Program. The data collected from these experiments will enhance the safety protocols for future space exploration missions. Ultimately, the insights gained from ROSIsat\u27s findings will have tangible implications for upcoming space endeavors
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Soil Compaction in Annual Crop Production Causes, Impacts, and Solutions
Soil compaction is commonly understood to be a serious and widespread concern for agricultural production and environmental health. It results in poor soil structure, restricted water movement, and reduced biological activity, ultimately reducing crop yield and other critical soil functions. Additionally, it can cause environmental damage by increasing the potential for soil erosion and associated surface water pollution. This damage and its consequences are particularly concerning given that soil regenerates so slowly that it can effectively be considered a nonrenewable resource. This publication examines how agricultural activities cause compaction, under what conditions soils are particularly susceptible to compaction, how it is identified and measured, and how it can be repaired using implements and through management practices, such as cover cropping
Cultivating engagement using our nursing professional practice model
A grassroots effort of nurse clinicians seeking to create a healthy work environment utilized all domains of the nursing professional practice model to create actionable items related to workplace violence
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