1,962 research outputs found
Approaches to Three-Dimensional Transformation Optical Media Using Quasi-Conformal Coordinate Transformations
We introduce an approach to the design of three-dimensional transformation
optical (TO) media based on a generalized quasi-conformal mapping approach. The
generalized quasi-conformal TO (QCTO) approach enables the design of media that
can, in principle, be broadband and low-loss, while controlling the propagation
of waves with arbitrary angles of incidence and polarization. We illustrate the
method in the design of a three-dimensional "carpet" ground plane cloak and of
a flattened Luneburg lens. Ray-trace studies provide a confirmation of the
performance of the QCTO media, while also revealing the limited performance of
index-only versions of these devices
Response to comment on 'Characteristics and screening history of women diagnosed with cervical cancer aged 20-29'
Companion modelling to enhance spring water collection and sharing in East Bhutan. CPWF PN25
Isotropic-medium three-dimensional cloaks for acoustic and electromagnetic waves
We propose a generalization of the two-dimensional eikonal-limit cloak
derived from a conformal transformation to three dimensions. The proposed cloak
is a spherical shell composed of only isotropic media; it operates in the
transmission mode and requires no mirror or ground plane. Unlike the well-known
omnidirectional spherical cloaks, it may reduce visibility of an arbitrary
object only for a very limited range of observation angles. In the
short-wavelength limit, this cloaking structure restores not only the
trajectories of incident rays, but also their phase, which is a necessary
ingredient to complete invisibility. Both scalar-wave (acoustic) and transverse
vector-wave (electromagnetic) versions are presented.Comment: 17 pages, 12 figure
Design, theory, and measurement of a polarization insensitive absorber for terahertz imaging
We present the theory, design, and realization of a polarization-insensitive
metamaterial absorber for terahertz frequencies. We derive
geometrical-independent conditions for effective medium absorbers in general,
and for resonant metamaterials specically. Our fabricated design reaches and
absorptivity of 78% at 1.145 ThzComment: 6 Pages, 5 figures; figures update
A statistical test of emission from unresolved point sources
We describe a simple test of the spatial uniformity of an ensemble of
discrete events. Given an estimate for the point source luminosity function and
an instrumental point spread function (PSF), a robust upper bound on the
fractional point source contribution to a diffuse signal can be found. We
verify with Monte Carlo tests that the statistic has advantages over the
two-point correlation function for this purpose, and derive analytic estimates
of the statistic's mean and variance as a function of the point source
contribution. As a case study, we apply this statistic to recent gamma-ray data
from the Fermi Large Area Telescope (LAT), and demonstrate that at energies
above 10 GeV, the contribution of unresolved point sources to the diffuse
emission is small in the region relevant for study of the WMAP Haze.Comment: 11 pages, 7 figures. Final version, accepted by Mon. Not. R. Astron.
Soc. The definitive version is available at www.blackwell-synergy.com
Who in Europe works beyond the state pension age and under which conditions? Results from SHARE
There is much research about those who exit the labour market prematurely, however, comparatively little is known about people working longer and about their employment and working conditions. In this paper, we describe the employment and working conditions of men and women working between 65 and 80 years, and compare them with previous conditions of those retired in the same age group. Analyses are based on wave 4 data from the Survey of Health, Ageing and Retirement in Europe (SHARE) with information collected between 2009 and 2011 from 17,625 older men and women across 16 European countries. Besides socio-demographic and health-related factors (physical and mental health), the focus lies on employment conditions (e.g. employment status, occupational position and working hours) and on stressful working conditions, measured in terms of low control at work and effort-reward imbalance. In case of retired people, information on working conditions refer to the last job before retirement. Following descriptive analyses, we then conduct multivariable analyses and investigate how working conditions and poor health are related to labour market participation (i.e. random intercept models accounting for country affiliation and adjusted for potential confounders). Results illustrate that people working between the ages of 65 and 80 are more likely to be self-employed (either with or without employees) and work in advantaged occupational positions. Furthermore, findings reveal that psychosocial working conditions are generally better than the conditions retired respondents had in their last job. Finally, in contrast to those who work, health tends to be worse among retired people. In conclusion, findings deliver empirical evidence that paid employment beyond age 65 is more common among self-employed workers throughout Europe, in advantaged occupations and under-favourable psychosocial circumstances, and that this group of workers are in considerably good mental and physical health. This highlights that policies aimed at increasing the state pension age beyond the age of 65 years put pressure on specific disadvantaged groups of men and women
A terahertz polarization insensitive dual band metamaterial absorber
Metamaterial absorbers have attracted considerable attention for applications in the terahertz range. In this Letter, we report the design, fabrication, and characterization of a terahertz dual band metamaterial absorber that shows two distinct absorption peaks with high absorption. By manipulating the periodic patterned structures as well as the dielectric layer thickness of the metal–dielectric–metal structure, significantly high absorption can be obtained at specific resonance frequencies. Finite-difference time-domain modeling is used to design the structure of the absorber. The fabricated devices have been characterized using a Fourier transform IR spectrometer. The experimental results show two distinct absorption peaks at 2.7 and 5.2 THz, which are in good agreement with the simulation. The absorption magnitudes at 2.7 and 5.2 THz are 0.68 and 0.74, respectively
The potential role of T-cells and their interaction with antigen-presenting cells in mediating immunosuppression following trauma-hemorrhage
Objective: Trauma-hemorrhage results in depressed immune responses of antigen-presenting cells (APCs) and T-cells. Recent studies suggest a key role of depressed T-cell derived interferon (IFN)-g in this complex immune cell interaction. The aim of this study was to elucidate further the underlying mechanisms responsible for dysfunctional T-cells and their interaction with APCs following trauma-hemorrhage.
Design: Adult C3H/HeN male mice were subjected to trauma-hemorrhage (3-cm midline laparotomy) followed by hemorrhage (blood pressure of 35�5mmHg for 90 min and resuscitation) or sham operation. At 24 h thereafter, spleens were harvested and T-cells (by Microbeads) and APCs (via adherence) were Isolated. Co-cultures of T-cells and APCs were established for 48 h and stimulated with concanavalin A and lipopolysaccharide. T-Cell specific cytokines known to affect APC function (i.e. interleukin(IL)-2, IL-4 and granulocyte-macrophage colony-stimulating factor (GM-CSF)) were measured in culture supernatants by Multiplex assay. The expression of MHC class II as well as co-stimulatory surface molecules on T-cells and APCs was determined by flow cytometry.
Results: The release of IL-4 and GM-CSF by T-cells was suppressed following trauma-hemorrhage, irrespective of whether sham or trauma-hemorrhage APCs were present. Antigen-presenting cells from animals subjected to trauma-hemorrhage did not affect T-cell derived cytokine release by sham T-cells. In contrast, T-cells from traumahemorrhage animals depressed MHC class II expression of CD11c(þ) cells, irrespective of whether APCs underwent sham or trauma-hemorrhage procedure. Surprisingly, co-stimulatory molecules on APCs (CD80, CD86) were not affected by trauma-hemorrhage.
Conclusions: These results suggest that beside IFN-g other T-cell derived cytokines contribute to immunosuppression following trauma-hemorrhage causing diminished MHC II expression on APCs. Thus, T-cells appear to play an important role in this interaction at the time-point examined. Therapeutic approaches should aim at maintenance of T-cell function and their interaction with APCs to prevent extended immunosuppression following trauma-hemorrhage
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