1,535 research outputs found

    Food security and Brexit: how the CAP began

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    In a new briefing paper, ‘Food, the UK and the EU: Brexit or Bremain?‘, Tim Lang and Victoria Schoen argue that post-Brexit the food world “will be characterised by volatility, disruption and uncertainty”, as the cost of imports will rise if sterling falls. They also discuss the urgent need for continued reform of the Common Agricultural Policy. In this extract from the paper, they explain how food and agriculture were central to the founding mission of the EU

    Open Notebook Science Challenge: Solubilities of Organic Compounds in Organic Solvents

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    This book contains the results of the Open Notebook Science Solubility Challenge. All experimental measurements are provided with a link to either the laboratory notebook page where the experiment was carried out or to a literature reference. The Challenge was sponsored by Submeta, Nature and Sigma-Aldrich

    Open Notebook Science Challenge: Solubilities of Organic Compounds in Organic Solvents

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    This book contains the results of the Open Notebook Science Solubility Challenge. All experimental measurements are provided with a link to either the laboratory notebook page where the experiment was carried out or to a literature reference. The Challenge was sponsored by Submeta, Nature and Sigma-Aldrich

    Soil Moisture Retrieval During a Corn Growth Cycle using L-band (1.6 GHz) Radar Observations

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    New opportunities for large-scale soil moisture monitoring will emerge with the launch of two low frequency (L-band 1.4 GHz) radiometers: the Aquarius mission in 2009 and the Soil Moisture and Ocean Salinity (SMOS) mission in 2008. Soil moisture is an important land surface variable affecting water and heat exchanges between atmosphere, land surface and deeper ground water reservoirs. The data products from these sensors provide valuable information in a range of climate and hydrologic applications (e.g., nume~cal weather prediction, drought monitoring, flood forecasting, water resources management, etc.). This paper describes a unique data set that was collected during a field campaign at OPE^ (Optimizing Production Inputs for Economic and Environmental Enhancements) site in Beltsville, Maryland throughout the eompj2ete corn growing in 2002. This investigation describes a simple methodology to correct active microwave observations for vegetation effects, which could potentially be implemented in a global soil moisture monitoring algorithm. The methodology has been applied to radar observation collected during the entire corn growth season and validation against ground measurements showed that the top 5-cm soil moisture can be retrieved with an accuracy up to 0.033 [cu cm/cu cm] depending on the sensing configuration

    Addressing policy challenges for more sustainable local-global food chains : policy frameworks and possible food ‘futures’

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    © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons by Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).The article considers how policy can address the local–global within a wider commitment to food sustainability and draws on research conducted for the EU-funded GLAMUR project (Global and local food assessment: a multidimensional performance-based approach). Case study data identifies four key policy challenges for policymakers. Addressing these challenges in order to make links between current (and future) more sustainable food policy involves three phases. The first identifies processes of engagement in three spheres (public policy, the market and civil society); the second identifies points of engagement offered by existing policy initiatives at global, EU, national and sub-national policy levels; and the third builds scenarios as possible “food futures”, used to illustrate how the project’s findings could impact on the “bigger policy picture” along the local–global continuum. Connections are made between the policy frameworks, as processes and points of engagement for food policy, and the food “futures”. It is suggested that the findings can help support policymakers as they consider the effects and value of using multi-criteria interventions.Peer reviewedFinal Published versio

    Estrogen induces global reorganization of chromatin structure in human breast cancer cells

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    In the cell nucleus, each chromosome is confined to a chromosome territory. This spatial organization of chromosomes plays a crucial role in gene regulation and genome stability. An additional level of organization has been discovered at the chromosome scale: the spatial segregation into open and closed chromatins to form two genome-wide compartments. Although considerable progress has been made in our knowledge of chromatin organization, a fundamental issue remains the understanding of its dynamics, especially in cancer. To address this issue, we performed genome-wide mapping of chromatin interactions (Hi-C) over the time after estrogen stimulation of breast cancer cells. To biologically interpret these interactions, we integrated with estrogen receptor α (ERα) binding events, gene expression and epigenetic marks. We show that gene-rich chromosomes as well as areas of open and highly transcribed chromatins are rearranged to greater spatial proximity, thus enabling genes to share transcriptional machinery and regulatory elements. At a smaller scale, differentially interacting loci are enriched for cancer proliferation and estrogen-related genes. Moreover, these loci are correlated with higher ERα binding events and gene expression. Taken together these results reveal the role of a hormone--estrogen--on genome organization, and its effect on gene regulation in cancer
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