1,132 research outputs found
Library Search UX report summer 2016
During Summer 2016, Imperial College London's Library Information Systems team ran a round of user experience research into the information-seeking behaviour of undergraduate and postgraduate students with a specific focus on the use of the library catalogue and discovery interface. The purpose of the work was to understand user behaviours and preferences to target development of practical improvements to the Library Search interface
Improving SIEM for critical SCADA water infrastructures using machine learning
Network Control Systems (NAC) have been used in many industrial processes. They aim to reduce the human factor burden and efficiently handle the complex process and communication of those systems. Supervisory control and data acquisition (SCADA) systems are used in industrial, infrastructure and facility processes (e.g. manufacturing, fabrication, oil and water pipelines, building ventilation, etc.) Like other Internet of Things (IoT) implementations, SCADA systems are vulnerable to cyber-attacks, therefore, a robust anomaly detection is a major requirement. However, having an accurate anomaly detection system is not an easy task, due to the difficulty to differentiate between cyber-attacks and system internal failures (e.g. hardware failures). In this paper, we present a model that detects anomaly events in a water system controlled by SCADA. Six Machine Learning techniques have been used in building and evaluating the model. The model classifies different anomaly events including hardware failures (e.g. sensor failures), sabotage and cyber-attacks (e.g. DoS and Spoofing). Unlike other detection systems, our proposed work helps in accelerating the mitigation process by notifying the operator with additional information when an anomaly occurs. This additional information includes the probability and confidence level of event(s) occurring. The model is trained and tested using a real-world dataset
Effect of Tuned Parameters on a LSA MCQ Answering Model
This paper presents the current state of a work in progress, whose objective
is to better understand the effects of factors that significantly influence the
performance of Latent Semantic Analysis (LSA). A difficult task, which consists
in answering (French) biology Multiple Choice Questions, is used to test the
semantic properties of the truncated singular space and to study the relative
influence of main parameters. A dedicated software has been designed to fine
tune the LSA semantic space for the Multiple Choice Questions task. With
optimal parameters, the performances of our simple model are quite surprisingly
equal or superior to those of 7th and 8th grades students. This indicates that
semantic spaces were quite good despite their low dimensions and the small
sizes of training data sets. Besides, we present an original entropy global
weighting of answers' terms of each question of the Multiple Choice Questions
which was necessary to achieve the model's success.Comment: 9 page
A combinatorial approach to knot recognition
This is a report on our ongoing research on a combinatorial approach to knot
recognition, using coloring of knots by certain algebraic objects called
quandles. The aim of the paper is to summarize the mathematical theory of knot
coloring in a compact, accessible manner, and to show how to use it for
computational purposes. In particular, we address how to determine colorability
of a knot, and propose to use SAT solving to search for colorings. The
computational complexity of the problem, both in theory and in our
implementation, is discussed. In the last part, we explain how coloring can be
utilized in knot recognition
The STAR MAPS-based PiXeL detector
The PiXeL detector (PXL) for the Heavy Flavor Tracker (HFT) of the STAR
experiment at RHIC is the first application of the state-of-the-art thin
Monolithic Active Pixel Sensors (MAPS) technology in a collider environment.
Custom built pixel sensors, their readout electronics and the detector
mechanical structure are described in detail. Selected detector design aspects
and production steps are presented. The detector operations during the three
years of data taking (2014-2016) and the overall performance exceeding the
design specifications are discussed in the conclusive sections of this paper
Pengaruh Pendidikan Kesehatan Hipertensi terhadap Pengetahuan Lansia di Posyandu Lansia Kelurahan Manisrenggo
Keluarga memiliki peran yang begitu penting bagi lansia yang menderita hipertensi khususnya dalam pemberian diet. Peran tersebut antara lain membimbing dan memecahkan masalah sehingga pemberian diet pada lansia dengan hipertensi dapat dikelola dengan baik oleh keluarga. Adapun penelitian ini bertujuan untuk mengetahui faktor-faktor yang berhubungan perilaku keluarga dalam pemberian diet hipertensi pada lansia. Faktor-faktornya adalah pengetahuan, sikap, umur, jenis kelamin, pendidikan, ketersediaan fasilitas kesehatan, dan tenaga kesehatan. Penelitian ini bersifat deskriptif analisis kuantitatif dengan menggunakan cross sectional. Jumlah sampel dalam penelitian ini sebanyak 30 responden. Pengambilan sampel menggunakan total sampling. Instrumen yang digunakan dalam penelitian ini adalah dengan wawancara menggunakan kuesioner. Data dianalisis dengan menggunakan analisis univariat dan analisis bivariat. Hasil analisis bivariat menunjukkan bahwa (a) ada hubungan antara pengetahuan dengan perilaku keluarga dalam pemberian diet hipertensi pada lansia ; (b) ada hubungan antara sikap dengan perilaku keluarga dalam pemberian diet hipertensi pada lansia ; (c) ada hubungan antara umur dengan perilaku keluarga dalam pemberian diet hipertensi pada lansia; (d) tidak ada hubungan antara jenis kelamin dengan perilaku keluarga dalam pemberian diet hipertensi pada lansia; (e) tidak ada hubungan antara pendidikan dengan perilaku keluarga dalam pemberian diet hipertensi pada lansia; (f) tidak ada hubungan antara ketersediaan fasilitas kesehatan dengan perilaku keluarga dalam pemberian diet hipertensi pada lansia; (g) tidak ada hubungan antara tenaga kesehatan dengan perilaku keluarga dalam pemberian diet hipertensi pada lansia. Keluarga perlu menyadari tentang pentingnya perannya dalam menjaga atau memantau nutrisi yang diberikan pada lansia dengan hipertensi. Keluarga dan penderita hipertensi harus bekerja sama agar penderita hipertensi patuh menjalani diet rendah garam agar tekanan darah penderita hipertensi dapat terkontrol dengan baik. Pada penelitian ini bahwa tingkat Pengaruh Pendidikan Kesehatan terhadap Pengetahuan Lansia di Posyandu Lansia Kelurahan Manisrenggo sebelum kita melakukan penyuluhan pada lansia dari 23 responden memiliki kategori cukup atau 43% dari 23 responden yaitu 10 responden. Namun, setelah kita melakukan penyuluhan tentang pengaruh pendidikan kesehatan terhadap pengetahuan lansia mengalami kenaikan dari 43% kategori cukup menjadi 52% memiliki kategori baik yaitu 12 orang
Strength Differential Measured in Inconel 718: Effects of Hydrostatic Pressure Studied
Aeropropulsion components, such as disks, blades, and shafts, are commonly subjected to multiaxial stress states at elevated temperatures. Experimental results from loadings as complex as those experienced in service are needed to help guide the development of accurate viscoplastic, multiaxial deformation models that can be used to improve the design of these components. During a recent study on multiaxial deformation (ref. 1) on a common aerospace material, Inconel 718, it was shown that the material in the aged state exhibits a strength differential effect (SDE), whereby the uniaxial compressive yield and subsequent flow behavior are significantly higher than those in uniaxial tension. Thus, this material cannot be described by a standard von Mises yield formulation. There have been other formulations postulated (ref. 2) that involve other combinations of the stress invariants, including the effect of hydrostatic stress. The question remained as to which invariants are necessary in the flow model. To capture the physical mechanisms occurring during deformation and reflect them in the plasticity formulation, researchers examined the flow of Inconel 718 under various amounts of hydrostatic stress to determine whether or not hydrostatic stress is needed in the formulation. Under NASA Grant NCC3-464, monitored by the NASA Glenn Research Center, a series of tensile tests were conducted at Case Western Reserve University on aged (precipitation hardened) Inconel 718 at 650 C and with superimposed hydrostatic pressure. Dogbone shaped tensile specimens (3-mm-diameter gauge by 16-mm gauge length) and cylindrical compression specimens (3-mm-diameter gauge by 6-mm gauge length) were strain gauged and loaded in a high-pressure testing apparatus. Hydrostatic pressures were obtained with argon and ranged from 210 to 630 MPa. The aged Inconel 718 showed a pronounced difference in the tension and compression yield strength (i.e., an SDE), as previously observed. Also, there were no significant effects of hydrostatic pressure on either the tensile and compressive yield strength (see the graph) or on the magnitude of the SDE. This behavior is not consistent with the pressure-dependent theory of the SDE, which postulates that the SDE is associated with pressure-dependent and/or internal friction dependent deformation associated with non-Schmid effects at the crystal level (refs. 3 and 4). Flow in Inconel 718 appears to be independent of hydrostatic pressure, suggesting that this invariant may be removed from the phenomenological constitutive model. As part of an ongoing effort to develop advanced constitutive models, Glenn s Life Prediction Branch coordinated this work with that of research on the multiaxial deformation behavior of Inconel 718 being conducted at Pennsylvania State University under NASA Grant NCC597
The inner centromere is a biomolecular condensate scaffolded by the chromosomal passenger complex.
The inner centromere is a region on every mitotic chromosome that enables specific biochemical reactions that underlie properties, such as the maintenance of cohesion, the regulation of kinetochores and the assembly of specialized chromatin, that can resist microtubule pulling forces. The chromosomal passenger complex (CPC) is abundantly localized to the inner centromeres and it is unclear whether it is involved in non-kinase activities that contribute to the generation of these unique chromatin properties. We find that the borealin subunit of the CPC drives phase separation of the CPC in vitro at concentrations that are below those found on the inner centromere. We also provide strong evidence that the CPC exists in a phase-separated state at the inner centromere. CPC phase separation is required for its inner-centromere localization and function during mitosis. We suggest that the CPC combines phase separation, kinase and histone code-reading activities to enable the formation of a chromatin body with unique biochemical activities at the inner centromere
Bacterial diversity in snow on North Pole ice floes
The microbial abundance and diversity in snow on ice floes at three sites near the North Pole was assessed using quantitative PCR and 454 pyrosequencing. Abundance of 16S rRNA genes in the samples ranged between 43 and 248 gene copies per millilitre of melted snow. A total of 291,331 sequences were obtained through 454 pyrosequencing of 16S rRNA genes, resulting in 984 OTUs at 97 % identity. Two sites were dominated by Cyanobacteria (72 and 61 %, respectively), including chloroplasts. The third site differed by consisting of 95 % Proteobacteria. Principal component analysis showed that the three sites clustered together when compared to the underlying environments of sea ice and ocean water. The Shannon indices ranged from 2.226 to 3.758, and the Chao1 indices showed species richness between 293 and 353 for the three samples. The relatively low abundances and diversity found in the samples indicate a lower rate of microbial input to this snow habitat compared to snow in the proximity of terrestrial and anthropogenic sources of microorganisms. The differences in species composition and diversity between the sites show that apparently similar snow habitats contain a large variation in biodiversity, although the differences were smaller than the differences to the underlying environment. The results support the idea that a globally distributed community exists in snow and that the global snow community can in part be attributed to microbial input from the atmosphere. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1007/s00792-014-0660-y) contains supplementary material, which is available to authorized users
Progression of Hypertrophy and Myocardial Fibrosis in Aortic Stenosis: A Multicenter Cardiac Magnetic Resonance Study
Background: Aortic stenosis is accompanied by progressive left ventricular hypertrophy and fibrosis. We investigated the natural history of these processes in asymptomatic patients and their potential reversal post-aortic valve replacement (AVR). Methods: Asymptomatic and symptomatic patients with aortic stenosis underwent repeat echocardiography and magnetic resonance imaging. Changes in peak aortic-jet velocity, left ventricular mass index, diffuse fibrosis (indexed extracellular volume), and replacement fibrosis (late gadolinium enhancement [LGE]) were quantified. RESULTS: In 61 asymptomatic patients (43% mild, 34% moderate, and 23% severe aortic stenosis), significant increases in peak aortic-jet velocity, left ventricular mass index, indexed extracellular volume, and LGE mass were observed after 2.1±0.7 years, with the most rapid progression observed in patients with most severe stenosis. Patients with baseline midwall LGE (n=16 [26%]; LGE mass, 2.5 g [0.8–4.8 g]) demonstrated particularly rapid increases in scar burden (78% [50%–158%] increase in LGE mass per year). In 38 symptomatic patients (age, 66±8 years; 76% men) who underwent AVR, there was a 19% (11%–25%) reduction in left ventricular mass index (P<0.0001) and an 11% (4%–16%) reduction in indexed extracellular volume (P=0.003) 0.9±0.3 years after surgery. By contrast midwall LGE (n=10 [26%]; mass, 3.3 g [2.6–8.0 g]) did not change post-AVR (n=10; 3.5 g [2.1–8.0 g]; P=0.23), with no evidence of regression even out to 2 years. Conclusions: In patients with aortic stenosis, cellular hypertrophy and diffuse fibrosis progress in a rapid and balanced manner but are reversible after AVR. Once established, midwall LGE also accumulates rapidly but is irreversible post valve replacement. Given its adverse long-term prognosis, prompt AVR when midwall LGE is first identified may improve clinical outcomes
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