Metaphysics and novel: Two pre-occupations of Antonio Rodríguez Huéscar

Este trabajo fue presentado en el encuentro académico La razón vital o histórica como proyecto metafísico en torno a don Antonio Rodríguez Huéscar, organizado por el Proyecto de Investigación FI 2009-11707 «La Escuela de Madrid y la búsqueda de una filosofía a la altura de los tiempos»Tratamos de mostrar los puntos de coincidencia entre la filosofía, entendida como comprensión de lo real, y la novela moderna, la que surge con Cervantes, como ficción que aspira a captar realidad, a partir del análisis de la novela que propone Antonio R. Huéscar. Dicho análisis es deudor de las categorías de la vida que él mismo contribuyó a establecer en sus ensayos críticos sobre la metafísica de la vida humana como «realidad radical» elaborada por José Ortega y Gasset a partir de los años treinta del siglo pasado. La narración es el instrumento esencial de que se sirven metafísica y novela para captar lo real, es decir, lo que acontece en las vidas de los hombres y mujeres que pueblan la tierraThis text will try to show the points of convergence between philosophy, seen as an understanding of reality, and modern novel, which is inaugurated by Cervantes, as fiction that aims to capture reality, from the analysis of the novel proposed by Antonio R. Huéscar. Such analysis is indebted to the categories of life which he helped establish in his critical essays about the metaphysics of human life as «radical reality», produced by José Ortega y Gasset from the thirties of the last century. Narration is the essential instrument used in metaphysics and novel to capture reality, that is, what happens in the lives of men and women who populate the eart

Dark Matter

Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2017, Tutor: Eduard Salvador SoléIn this paper, we introduce the astrophysical problem of dark matter (DM) mainly focusing on the observational/experimental point of view. Even though DM cannot be observed directly, there are plenty of indirect observations supporting that there is more mass than we can see. This is the case for the observed properties of galaxies, galaxy clusters and the large-scale structure of the universe. We mention the implications of DM in astrophysics and high-energy physics. We then describe the DM candidates. The first group is the ordinary DM, also known as baryonic DM, in the form of astrophysical objects. The second group is non-ordinary DM or non-baryonic DM. This group encompasses all the solutions for the problem that are not in the Standard Model (SM) of particle physics. We end up by reviewing some current experiments that could allow us to discover what kind of DM we are facing

Apparent time variation in Basque: variation in Aramaio and Otxandio

In this paper we want to research the sociolinguistic variation among people speaking dialect. The research has been made in two villages, in Aramaio and in Otxandio. This is a small sample of a wider project carried out by the research team EUDIA of the University of the Basque Country. The name of the project is EAS (Euskararen Atlas sozio-geolinguistikoa or Socio and geo-linguistic atlas of the Basque language). In this project an enquiry is carried out in 100 villages of the Basque speaking area (in the seven provinces). The questionnaire has about 200 questions (which cover different fields of the language: lexicon, noun morphology, verb morphology and syntax). The questionnaire is done in each village and the respondents are two male speakers, one of them young and the other mature. We want to know what the linguistic differentiations are (in lexicon, in morphology and in syntax) between young and middle aged people. Moreover, we have paid special attention to measure the influence of Unified Basque

Metodología de enseñanza en padel en niveles de iniciación

El objetivo principal del presente artículo es el aportar datos relacionados con las características que presenta la enseñanza y el aprendizaje del padel en niveles de iniciación. Algunos de los resultados obtenidos nos permiten identificar la existencia de un enfoque plurimetodológico que incide en los aspectos técnicos y tácticos de esta práctica deportiva. A estas conclusiones se han llegado gracias a las informaciones aportadas por el alumnado, los entrenadoresThe main objective of this research work is to present some data related with the main characteristics of the teaching and learning of paddle tennis at beginner’s level. Some of the results obtained, shows that there is a multi methodology approach which focus on the technical and tactical aspects of this sport. These conclusions were reached thanks to the information provided by players (learners) and coache

Antonio Rodríguez Huéscar and José Ortega y Gasset: Three Letters

El objetivo principal de este artículo es comentar las cartas que se enviaron Antonio Rodríguez Huéscar y José Ortega y Gasset entre 1942 y 1943. Dichas cartas se incluyen en el artículo.The principal aim of this paper is to comment on the letters which Antonio Rodríguez Huéscar and José Ortega y Gasset sent each other between 1942 and 1943. The above said letters are included in the pape

Effect of NDP-a-MSH on PPAR-c and –b Expression and Anti-Inflammatory Cytokine Release in Rat Astrocytes and Microglia

Brain inflammation plays a central role in numerous brain pathologies. Microglia and astrocytes are the main effector cells that become activated when an inflammatory process takes place within the central nervous system. a-melanocytestimulating hormone (a-MSH) is a neuropeptide with proven anti-inflammatory properties. It binds with highest affinity to the melanocortin receptor 4 (MC4R), which is present in astrocytes and upon activation triggers anti-inflammatory pathways. The aim of this research was to identify anti-inflammatory mediators that may participate in the immunomodulatory effects of melanocortins in glial cells. Since peroxisome proliferator-activated receptors (PPARs) have recently been implicated in the modulation of inflammation, we investigated the effect of an a-MSH analog, [Nle4 , D-Phe7]- a-MSH (NDP-a-MSH), on PPAR-b and PPAR-c gene and protein expression in rat primary astrocytes and microglia. We initially demonstrated that rat primary microglia express MC4R and showed that treatment with NDP-a-MSH increases PPAR-c protein levels and strongly decreases PPAR-b levels in both astrocytes and microglia. We also showed that extracellular signal-regulated kinase 1/2 (ERK1/2)–mediated signaling is partially involved in these effects in a cell-specific fashion. Finally, we showed that NDP-a-MSH stimulates the release of the anti-inflammatory cytokines IL-10 and TGF-b from microglia and astrocytes, respectively. The presented data suggest a role for IL-10 and TGF-b in the protective action of melanocortins and a connection between MC4R pathway and that of the nuclear receptor PPAR-c. This is the first report providing evidence that MC4R is expressed in rat primary microglia and that melanocortins modulate PPAR levels in glial cells. Our findings provide new insights into the mechanisms underlying the activation of glial MC4R and open perspectives for new therapeutic strategies for the treatment of inflammation-mediated brain diseases.Fil: Carniglia, Lila. INSTITUTO DE INVESTIGACIONES BIOMEDICAS;Fil: Durand, Daniela Elizabeth. INSTITUTO DE INVESTIGACIONES BIOMEDICAS;Fil: Caruso, Carla Mariana. INSTITUTO DE INVESTIGACIONES BIOMEDICAS;Fil: Lasaga, Mercedes Isabel. INSTITUTO DE INVESTIGACIONES BIOMEDICAS

Hydrogen bonded complexes between nitrogen dioxide, nitric acid, nitrous acid and water with SiH3OH and Si(OH)4

The inter-conversion of nitrogen oxides and oxy acids on silica surfaces is of major atmospheric importance. As a preliminary step towards rationalising experimental observations, and understanding the mechanisms behind such reactions we have looked at the binding energies of NO2, N2O4, HNO3, HONO and H2O with simple proxies of a silica surface, namely SiH3OH and Si(OH)4 units. The geometries of these molecular clusters were optimised at both HF/6-311+G(d) and B3LYP/6-311+G(d) level of theory. The SCF energies of the species were determined at the HF/6-311++G(3df,2pd) and B3LYP/6-311++G(3df,2pd) level. The values indicate that nitric acid is by far the most strongly bound species, in agreement with experimental observations. It was also found that the dimer N2O4 is significantly more strongly bound to the Si(OH)4 and SiH3OH units than NO2 itself. The vibrational frequencies calculated for the hydrogen-bonded complexes are compared to the experimentally observed frequencies of the adsorbed species where possible

Evaluation of the training of early Chilhood Education teachers in Psychomotricity

Con nuestra investigación queremos conocer aspectos relacionados con la formación de los docentes de Educación Infantil sobre Psicomotricidad. La muestra con la que hemos trabajado ha sido de n= 76 sujetos, a los que se les ha pasado un cuestionario del que destacamos los siguientes resultados: más de la mitad de la muestra ha recibido tanto formación inicial como formación continua en Psicomotricidad. El 92 % la realiza en sus clases, al sentirse capacitado para ello. Podemos concluir afirmando que el profesorado que imparte docencia en la etapa de infantil considera importante el trabajo de psicomotricidad en sus clases y como consecuencia lo realizan