759 research outputs found
Proposition of a benchmark for evaluation of cores mapping onto NoC architectures
Proposition of a MC-CDMA Radiocommunication benchmark for evaluation of cores mapping onto NoC architectures. Illustration with CEA-LETI FAUST NoC in the context of 4-more European project
Overview of laboratory methods to diagnose Leptospirosis and to identify and to type leptospires
Leptospirosis is a virulent zoonosis with a global distribution. Pathogenic spirochetes of the genus Leptospira are responsible for this disease, and the primary animal reservoirs are rodentvvvs. Direct and indirect contact with infected urine constitutes the main route of transmission. Renal failure and advanced abortions are frequently observed in animals affected by leptospirosis, causing serious problems for farms. In humans, there is a high rate of mortality (10 percent), and farmers and persons in contact with water are frequently exposed. However, vaccines and strict prevention measures confer protection against leptospirosis. Serological tests facilitate the detection and identification of leptospire strains. Such tests are based on specific surface antigen recognition and are used for clinical analyses. To determine which serovars circulate in the environment, leptospires must be typed. Molecular methods, such as restriction enzyme-based techniques and the sequencing of specific regions, permit serovar identification. Unfortunately, although there are numerous techniques, they are not very efficient, and thus, new methods must be developed. With the advent of genomic sequencing, a substantial amount of information regarding leptospire genomes is now available, facilitating the selection of regions to discriminate between strains. Typing is important for both epidemiologic purposes and clinical analyses.Keywords: Leptospirosis · zoonosis · methods · diagnosi
Flexible and Distributed Real-Time Control on a 4G Telecom MPSoC
International audienceApplications like 4G baseband modem require single-chip implementation to meet the integration and power consumption requirements. These applications demand a high computing performance with real-time constraints, low-power consumption and low cost. With the rapid evolution of telecom standards and the increasing demand for multi-standard products, the need for exible baseband solutions is growing. The concept of Multi-Processor System-on-Chip (MPSoC) is well adapted to enable hardware reuse between products and between multiple wireless standards in the same device. Based on the experience of two heterogeneous Software Defined Radio (SDR) telecom chipsets, this paper presents a distributed control architecture for the homoGENEous Processor arraY (GENEPY) platform for 4G applications. This MPSoC platform is built with telecom baseband processors interconnected with a Network-on-Chip. The control is performed by a MIPS processor embedded in each baseband processor. This control processor can locally reconfigure and schedule the applications with real-time telecom constraints
Heterogeneous vs Homogeneous MPSoC Approaches for a Mobile LTE Modem
International audienceApplications like 4G baseband modem require single-chip implementation to meet the integration and power consumption requirements. These applications demand a high computing performance with real-time constraints, low-power consumption and low cost. With the rapid evolution of tele- com standards and the increasing demand for multi-standard products, the need for flexible baseband solutions is growing. The concept of Multi-Processor System-on-Chip (MPSoC) is well adapted to enable hardware reuse between products and between multiple wireless standards in the same device. Heterogeneous architectures are well known solutions but they have limited flexibility. Based on the experience of two heterogeneous Software De- fined Radio (SDR) telecom chipsets, this paper presents the homoGENEous Processor arraY (GENEPY) platform for 4G ap- plications. This platform is built with SMEP units interconnected with a Network-on-Chip. The SMEP, implemented in 65nm low- power CMOS, can perform 3.2 GMAC/s with 77 GBits/s internal bandwidth at 400MHz. Two implementations of homogeneous GENEPY are compared to the heterogeneous MAGALI platform in terms of silicon area, performance and power consumption. Results show that a homogeneous approach can be more efficient and flexible than a heterogeneous approach in the context of 4G Mobile Terminals
Structural mechanism of anticoagulant rodenticides resistances: Identification of a hydrophobic cluster responsible for the affinity between inhibitors and the target protein
Comparative Biology of the Resistance to Vitamin K Antagonists: An Overview of the Resistance Mechanisms
Vitamin K antagonists (VKA) are used in human medicine as well as for the management of rodent populations. In both cases, we have to deal with inter-individual resistances. Many mechanisms of resistances are common in humans and rodents. Moreover, with the large use of vitamin K antagonist rodenticides, the resistant phenotype is overrepresented in some rodent populations. Consequently, some resistance mechanisms with a low prevalence in the human population have a higher prevalence in rodent population; thus, they can be more studied in rodents. The aim of this chapter is to cross knowledge coming from human medicine and rodent research in order to better understand each resistance mechanism. After an overview of the essential knowledge for the understanding of the VKA action, this chapter presents the different methods of VKA resistance studying and then it assesses the current knowledge on VKA resistance in humans and rodents
3D advanced integration technology for heterogeneous systems
International audience3D integration technology is nowadays mature enough, offering today further system integration using heterogeneous technologies, with already many different industrial successes (Imagers, 2.5D Interposers, 3D Memory Cube, etc.). CEA-LETI has been developing for a decade 3D integration, and have pursued research in both directions: developing advanced 3D technology bricks (TSVs, µ-bumps, Hybrid Bonding, etc), and designing advanced 3D circuits as pioneer prototypes. In this paper, a short overview of some recent advanced 3D technology results is presented, including some latest 3D circuit's description
Kombilohn et salaire minimum : la fin de l’exception allemande
Kombilohn et/ou salaire minimum : un débat approche de son terme. A la fin novembre 2006, une commission présidée par Franz Müntefering présentera en effet, conformément aux dispositions de l’accord de coalition, des propositions sur un sujet brûlant : l’emploi pour les salariés peu qualifiés. Il faudra alors passer à la décision politique, phase qui s’annonce particulièrement difficile, tant la négociation touche à des aspects économiquement et socialement sensibles.Malgré la divergence de leurs approches, expressément consignée dans l’accord de coalition, chrétiens-démocrates et sociaux-démocrates partent au moins du même constat : l’accès au marché du travail des actifs peu qualifiés passe par des emplois mal rémunérés qui nécessitent une double intervention. D’une part, il faut, pour favoriser leur émergence, améliorer le système de subventions et de compléments salariaux qui les encadrent déjà. C’est à ces dispositifs d’aide à l’emploi que renvoie le terme de Kombilohn, appliqué de manière générique à toutes les combinaisons de revenus d’activité et de revenus de transfert conçues pour le secteur des bas salaires. Mais d’autre part, l’extension de ce secteur à bas salaires génère de plus en plus souvent des rémunérations « immorales » (sittenwidrig : la jurisprudence désigne ainsi les salaires inférieurs d’un tiers au salaire conventionnel ou aux salaires localement usités), qui justifient quant à elles que soit discutée l’opportunité d’un salaire minimum
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