92 research outputs found

    Highly Efficient Midinfrared On-Chip Electrical Generation of Graphene Plasmons by Inelastic Electron Tunneling Excitation

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    Inelastic electron tunneling provides a low-energy pathway for the excitation of surface plasmons and light emission. We theoretically investigate tunnel junctions based on metals and graphene. We show that graphene is potentially a highly efficient material for tunneling excitation of plasmons because of its narrow plasmon linewidths, strong emission, and large tunability in the midinfrared wavelength regime. Compared to gold and silver, the enhancement can be up to 10 times for similar wavelengths and up to 5 orders at their respective plasmon operating wavelengths. Tunneling excitation of graphene plasmons promises an efficient technology for on-chip electrical generation and manipulation of plasmons for graphene-based optoelectronics and nanophotonic integrated circuits.Comment: 12 pages, 7 figure

    Replication Study: Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis

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    As part of the Reproducibility Project: Cancer Biology we published a Registered Report (Fiering et al., 2015) that described how we intended to replicate selected experiments from the paper ‘Biomechanical remodeling of the microenvironment by stromal caveolin-1 favors tumor invasion and metastasis’ (Goetz et al., 2011). Here we report the results. Primary mouse embryonic fibroblasts (pMEFs) expressing caveolin 1 (Cav1WT) demonstrated increased extracellular matrix remodeling in vitro compared to Cav1 deficient (Cav1KO) pMEFs, similar to the original study (Goetz et al., 2011). In vivo, we found higher levels of intratumoral stroma remodeling, determined by fibronectin fiber orientation, in tumors from cancer cells co-injected with Cav1WT pMEFs compared to cancer cells only or cancer cells plus Cav1KO pMEFs, which were in the same direction as the original study (Supplemental Figure S7C; Goetz et al., 2011), but not statistically significant. Primary tumor growth was similar between conditions, like the original study (Supplemental Figure S7Ca; Goetz et al., 2011). We found metastatic burden was similar between Cav1WT and Cav1KO pMEFs, while the original study found increased metastases with Cav1WT (Figure 7C; Goetz et al., 2011); however, the duration of our in vivo experiments (45 days) were much shorter than in the study by Goetz et al. (2011) (75 days). This makes it difficult to interpret the difference between the studies as it is possible that the cells required more time to manifest the difference between treatments observed by Goetz et al. We also found a statistically significant negative correlation of intratumoral remodeling with metastatic burden, while the original study found a statistically significant positive correlation (Figure 7Cd; Goetz et al., 2011), but again there were differences between the studies in terms of the duration of the metastasis studies and the imaging approaches that could have impacted the outcomes. Finally, we report meta-analyses for each result

    Developmental regulation

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    THE CONTENT OF TEXT BOOKS USED IN KINDERGARTEN EDUCATION IN SINGAPORE

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    Master'sMASTER OF SOCIAL SCIENCES (APPLIED SOCIOLOGY

    Modification of SOVA-based Algorithms for Efficient Hardware Implementation

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    In this paper, a modified soft-output Viterbi algorithm (SOVA) is presented to enable efficient hardware implementation. The forward-only processing of the SOVA has an inherent lower latency than forward-backward algorithms such as BCJR and its offspring, which are commonly used in iterative decoders. Thus, SOVA-based architectures require less parallelization and therefore hardware for the same data throughput. A simplification is proposed to the Battail rule ( BR) SOVA to approximate the concurrent path reliability values with the corresponding metric differences. This simplified BR-SOVA (SB-SOVA) performs close to max-log-MAP. Furthermore, a novel hybrid decoding architecture is proposed that combines the simplicity of the original Hagenauer rule and the performance-preserving properties of the SB-SOVA to trade implementation complexity for decoding performance. The hybrid approach is evaluated with practical link-level simulations of the downlink data channel in LTE Rel-8

    Modification of SOVA-based Algorithms for Efficient Hardware Implementation

    No full text
    In this paper, a modified soft-output Viterbi algorithm (SOVA) is presented to enable efficient hardware implementation. The forward-only processing of the SOVA has an inherent lower latency than forward-backward algorithms such as BCJR and its offspring, which are commonly used in iterative decoders. Thus, SOVA-based architectures require less parallelization and therefore hardware for the same data throughput. A simplification is proposed to the Battail rule ( BR) SOVA to approximate the concurrent path reliability values with the corresponding metric differences. This simplified BR-SOVA (SB-SOVA) performs close to max-log-MAP. Furthermore, a novel hybrid decoding architecture is proposed that combines the simplicity of the original Hagenauer rule and the performance-preserving properties of the SB-SOVA to trade implementation complexity for decoding performance. The hybrid approach is evaluated with practical link-level simulations of the downlink data channel in LTE Rel-8
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