Computer program simplifies design of rotating components of turbomachinery

Digital computer program performs stress analysis and burst speed calculations on rotating axisymmetric turbomachinery components. The computer printout contains the displacement of each nodal point, the stress at the center of each element, the average tangential stress within the component, and the burst speed

Status of the ILC Main Linac BPM R&D

An introduction and the status of R&D activities for a high-resolution, "cold" beam position monitor (BPM) and the related read-out electronics are discussed. Two different BPM detector concepts, to be attached to the SC quadrupole and located inside the ILC cryomodule, are currently under investigation: A resonant dipole-mode cavity-style BPM pickup, developed at Fermilab, and a re-entrant resonant coaxial waveguide BPM, designed by CEA-Saclay. While the 1.5 GHz dipole-mode cavity BPM is still in the R&D phase, the re-entrant BPM has already passed first beam tests, including its read-out system. Furthermore, the LAPP group is developing radiation tolerant digital read-out systems, which are tested at the CLIC test facility (CTF).Comment: LCWS / ILC08 conference contribution, 6 pages, 6 figure

The replacement histone H2A.Z in a hyperacetylated form is a feature of active genes in the chicken

The replacement histone H2A.Z is variously reported as being linked to gene expression and preventing the spread of heterochromatin in yeast, or concentrated at heterochromatin in mammals. To resolve this apparent dichotomy, affinity-purified antibodies against the N-terminal region of H2A.Z, in both a triacetylatedandnon- acetylatedstate, areusedin native chromatin immmuno-precipitation experiments with mononucleosomes from three chicken cell types. The hyperacetylated species concentrates at the 50 end of active genes, both tissue specific and housekeeping but is absent from inactive genes, while the unacetylated form is absent from both active and inactive genes. A concentration of H2A.Z is also found at insulators under circumstances implying a link to barrier activity but not to enhancer blocking. Although acetylated H2A.Z is widespread throughout the interphase genome, at mitosis its acetylation is erased, the unmodified form remaining. Thus, although H2A.Z may operate as an epigenetic marker for active genes, its N-terminal acetylation does not

Integrating Grounding in the Search Process for Answer Set Computing

Answer Set Programming (ASP) is a very convenient paradigmto represent knowledge in Artificial Intelligence and to encode Constraint Satisfaction Problems. For that, the natural way to use ASP is to elaborate a first order logic program with default negation encoding the problem to solve. In a preliminary step this program is translated in an equivalent propositional one by a first tool: the grounder. Then, the propositional program is given to a second tool: the solver. This last one computes (if they exist) one or many answer sets (models) of the program, each answer set encoding one solution of the initial problem. Today, we can say that almost all ASP solvers follow this approach of two steps computation. In this work, we begin by putting in evidence that sometimes the preliminary grounding phase is the only bottleneck for the answer set computation. We show that a lot of useless and counterintuitive work is done in some situations. But, our major contribution is to introduce a new approach of answer set computing that escapes the preliminary phase of rule instantiation by integrating it in the search process. Furthermore, we describe the main lines of the first implementation of our new ASP solver ASPeRiX developed following the introduced methodology

Atomic Modeling of Photoionization Fronts in Nitrogen Gas

Photoionization fronts play a dominant role in many astrophysical environments, but remain difficult to achieve in a laboratory experiment. Recent papers have suggested that experiments using a nitrogen medium held at ten atmospheres of pressure that is irradiated by a source with a radiation temperature of T$_{\rm R}\sim$ 100 eV can produce viable photoionization fronts. We present a suite of one-dimensional numerical simulations using the \helios\ multi-material radiation hydrodynamics code that models these conditions and the formation of a photoionization front. We study the effects of varying the atomic kinetics and radiative transfer model on the hydrodynamics and ionization state of the nitrogen gas, finding that more sophisticated physics, in particular a multi-angle long characteristic radiative transfer model and a collisional-radiative atomics model, dramatically changes the atomic kinetic evolution of the gas. A photoionization front is identified by computing the ratios between the photoionization rate, the electron impact ionization rate, and the total recombination rate. We find that due to the increased electron temperatures found using more advanced physics that photoionization fronts are likely to form in our nominal model. We report results of several parameter studies. In one of these, the nitrogen pressure is fixed at ten atmospheres and varies the source radiation temperature while another fixes the temperature at 100 eV and varied the nitrogen pressure. Lower nitrogen pressures increase the likelihood of generating a photoionization front while varying the peak source temperature has little effect.Comment: 17 pages, 10 figures, accepted to physics of plasma

Possibilistic Uncertainty Handling for Answer Set Programming

In this work, we introduce a new framework able to deal with a reasoning that is at the same time non monotonic and uncertain. In order to take into account a certainty level associated to each piece of knowledge, we use possibility theory to extend the non monotonic semantics of stable models for logic programs with default negation. By means of a possibility distribution we define a clear semantics of such programs by introducing what is a possibilistic stable model. We also propose a syntactic process based on a fix-point operator to compute these particular models representing the deductions of the program and their certainty. Then, we show how this introduction of a certainty level on each rule of a program can be used in order to restore its consistency in case of the program has no model at all. Furthermore, we explain how we can compute possibilistic stable models by using available softwares for Answer Set Programming and we describe the main lines of the system that we have developed to achieve this goal

SigTree: A Microbial Community Analysis Tool to Identify and Visualize Significantly Responsive Branches in a Phylogenetic Tree.

Microbial community analysis experiments to assess the effect of a treatment intervention (or environmental change) on the relative abundance levels of multiple related microbial species (or operational taxonomic units) simultaneously using high throughput genomics are becoming increasingly common. Within the framework of the evolutionary phylogeny of all species considered in the experiment, this translates to a statistical need to identify the phylogenetic branches that exhibit a significant consensus response (in terms of operational taxonomic unit abundance) to the intervention. We present the R software package SigTree, a collection of flexible tools that make use of meta-analysis methods and regular expressions to identify and visualize significantly responsive branches in a phylogenetic tree, while appropriately adjusting for multiple comparisons

2-Dust : a Dust Radiative Transfer Code for an Axisymmetric System

We have developed a general purpose dust radiative transfer code for an axisymmetric system, 2-Dust, motivated by the recent increasing availability of high-resolution images of circumstellar dust shells at various wavelengths. This code solves the equation of radiative transfer following the principle of long characteristic in a 2-D polar grid while considering a 3-D radiation field at each grid point. A solution is sought through an iterative scheme in which self-consistency of the solution is achieved by requiring a global luminosity constancy throughout the shell. The dust opacities are calculated through Mie theory from the given size distribution and optical properties of the dust grains. The main focus of the code is to obtain insights on (1) the global energetics of dust grains in the shell (2) the 2-D projected morphologies that are strongly dependent on the mixed effects of the axisymmetric dust distribution and inclination angle of the shell. Here, test models are presented with discussion of the results. The code can be supplied with a user-defined density distribution function, and thus, is applicable to a variety of dusty astronomical objects possessing the axisymmetric geometry.Comment: To be published in ApJ, April 2003 issue; 13 pages, 4 tables, 17 figures, 5-page appendix (no figures for the main text included in this preprint). For the complete preprint and code distribution, contact the author

The replacement histone H2A.Z in a hyperacetylated form is a feature of active genes in the chicken

The replacement histone H2A.Z is variously reported as being linked to gene expression and preventing the spread of heterochromatin in yeast, or concentrated at heterochromatin in mammals. To resolve this apparent dichotomy, affinity-purified antibodies against the N-terminal region of H2A.Z, in both a triacetylatedandnon- acetylatedstate, areusedin native chromatin immmuno-precipitation experiments with mononucleosomes from three chicken cell types. The hyperacetylated species concentrates at the 50 end of active genes, both tissue specific and housekeeping but is absent from inactive genes, while the unacetylated form is absent from both active and inactive genes. A concentration of H2A.Z is also found at insulators under circumstances implying a link to barrier activity but not to enhancer blocking. Although acetylated H2A.Z is widespread throughout the interphase genome, at mitosis its acetylation is erased, the unmodified form remaining. Thus, although H2A.Z may operate as an epigenetic marker for active genes, its N-terminal acetylation does not