50 research outputs found

    Chemical evaluations of John F. Baldwin Ship Channel sediment phase 2

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    In August of 1990, the battelle/Marine Sciences Laboratory (MSL) conducted a program of sampling, geologic characterization, and chemical analysis of sediments from five sites in the West Richmond reach of the John F. Baldwin Ship Channel in San Francisco Bay. Additional sediment samples were collected for the USACE Waterways Experiment Station (WES) Wetlands and Uplands testing programs. The objective of the MSL study of the five West Richmond sites was to determine the physical characteristics and chemical contaminant levels in sediments proposed for dredging. Metals concentrations were comparable to or lower than those reported in the Phase 1 study. Butyltin concentrations were very low, and organic contaminants (PAH, PCB and pesticides) were not detected. Differences between Phase 1 and Phase 2 results may be explained by the fact that Phase 2 stations are outside the shipping channel. 16 refs., 4 figs., 16 tabs

    The clinical outcome of restricting drug-eluting stents to patients at highest risk of restenosis

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    AIMS: To assess the clinical outcomes of patients where drug eluting stents (DES) were restricted to those at highest risks of restenosis, we compared three different strategies for stent implantation: bare metal stents (BMS) only, DES only and a group where DES use was restricted (RES). METHOD AND RESULTS: Initial comparison was made between BMS only (279 patients, 316 lesions) and DES only (272 patients, 302 lesions). The endpoints of death, non-fatal myocardial infarction and target lesion revascularisation (TLR) [MACE] were assessed at 12 months. The incidence of MACE in the BMS only and DES only groups were 14% and 7% (p=0.002) and TLR was 8% and 1% (p<0.0001). Comparison was then made between these results and a third group where DES was restricted to patients at highest risk of restenosis. The restricted group (RES) comprised 249 patients (271 lesions) of which 53% received DES. RES remained significantly better than BMS, MACE (14% vs. 8%, p=0.02) and TLR (8% vs. 3%, p=0.02). When RES was compared with DES only, there was no significant difference in MACE (8% vs. 7% p=0.42), but there was a significantly lower TLR rate in the DES only group (1% vs. 3% p=0.04). CONCLUSIONS: The overall incidence of events in patients where DES use was restricted to 53% of patients remains low and this may be an acceptable treatment strategy to reduce costs.6 page(s
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