Poland\u27s Ex--Communists: From Pariahs to Establishment Players

The Polish United Workers\u27 Party (Polska Zjednoczona Partia Robotnicza [PZPR]) suffered what seemed to be a terminal blow in 1989. In elections rigged so that the communists and their old allies were guaranteed 65 percent of the seats in the main house of parliament, the communists did so badly that their old allies deserted them. After what appeared to be a total defeat, all the communist reformers could do was turn the government over to the men and women of Solidarity they had interned and harassed for more than a decade. Then they had to disband themselves and form a new party to inherit the tattered remains of their mantle and resources. Less than four years after what looked like a complete rejection, in the 1993 free parliamentary elections, the successor party to the PZPR, the Social Democrats of Poland (Socjaldemokracja Rzeczypospolitej Polskiej [SdRP]), and its coalition, the Democratic Left Alliance (Sojusz Lewicy Demokratycznej [SLD]), did well enough to dominate the parliament and form a government. Two years later, in 1995, the leader of the SdRP and its coalition\u27s presidential candidate, Aleksander Kwasniewski (a junior member of that last communist government), soundly defeated the Solidarity leader and incumbent president, Lech Wałesa. By 1999, when the coalition turned itself into a party, the SLD was, by far, both the most popular and the most stable party in democratic Poland. As a result, it dominated the parliamentary elections of 2001, leaving Solidarity\u27s old parties so fragmented that they did not get enough of the votes to get seats. In the process, it raised the population\u27s hopes that it could solve Poland\u27s economic problems and bring the same economic boom Poles remembered from 1993 to 1997

Patentable Subject [Anti]matter

The statements, The laws of nature, the principles of nature, the fundamental truths, etc., are not patentable, have been oft repeated but seldom understandingly used. They have led to misunderstanding and much confusion, not limited to members of the bar. In fact, the words... are all words of broad and also elastic meaning and are frequently used carelessly and without any attempt at refined distinctions

Evolutionary biology and genetic techniques for insect control

The requirement to develop new techniques for insect control that minimize negative environmental impacts has never been more pressing. Here we discuss population suppression and population replacement technologies. These include sterile insect technique, genetic elimination methods such as the release of insects carrying a dominant lethal (RIDL), and gene driving mechanisms offered by intracellular bacteria and homing endonucleases. We also review the potential of newer or underutilized methods such as reproductive interference, CRISPR technology, RNA interference (RNAi), and genetic underdominance. We focus on understanding principles and potential effectiveness from the perspective of evolutionary biology. This offers useful insights into mechanisms through which potential problems may be minimized, in much the same way that an understanding of how resistance evolves is key to slowing the spread of antibiotic and insecticide resistance. We conclude that there is much to gain from applying principles from the study of resistance in these other scenarios – specifically, the adoption of combinatorial approaches to minimize the spread of resistance evolution. We conclude by discussing the focused use of GM for insect pest control in the context of modern conservation planning under land-sparing scenarios

Which Way is Right?

LEFT, Right, But Always Forward was this year\u27s election slogan for the Freedom Union, whose leaders went from anti-communist opposition to head the first noncommunist government in Poland in 1989. Today\u27s Polish party leaders show the same lack of concern with traditional political definitions. Back when the Communist Party was voted out, the meaning of the election seemed clear to most voters: the choice was for or against continued communist control. Now, left and right have blurred and compromised. Parties focus on political theory rather than on voters\u27 legitimate concerns about the economy. As a result, last month\u27s elections in Poland presented no clear options for voters

Expanding the CRISPR toolbox in Culicine mosquitoes: in vitro validation of Pol III promoters

CRISPR–Cas9-based “gene drive” technologies have been proposed as a novel and effective means of controlling human diseases vectored by mosquitoes. However, more complex designs than those demonstrated to date—and an expanded molecular toolbox with which to build them—will be required to overcome the issues of resistance formation/evolution and drive spatial/temporal limitation. Foreseeing this need, we assessed the sgRNA transcriptional activities of 33 phylogenetically diverse insect Polymerase III promoters using three disease-relevant Culicine mosquito cell lines (Aedes aegypti, Aedes albopictus, and Culex quinquefasciatus). We show that U6 promoters work across species with a range of transcriptional activity levels and find 7SK promoters to be especially promising because of their broad phylogenetic activity. We further show that U6 promoters can be substantially truncated without affecting transcriptional levels. These results will be of great utility to researchers involved in developing the next generation of gene drives

Rad-Tolerant, Thermally Stable, High-Speed Fiber-Optic Network for Harsh Environments

Future NASA destinations will be challenging to get to, have extreme environmental conditions, and may present difficulty in retrieving a spacecraft or its data. Space Photonics is developing a radiation-tolerant (rad-tolerant), high-speed, multi-channel fiber-optic transceiver, associated reconfigurable intelligent node communications architecture, and supporting hardware for intravehicular and ground-based optical networking applications. Data rates approaching 3.2 Gbps per channel will be achieved

Diet, Gut Microbes and Host Mate Choice:Understanding the significance of microbiome effects on host mate choice requires a case by case evaluation

All organisms live in close association with microbes. However, not all such associations are meaningful in an evolutionary context. Current debate concerns whether hosts and microbes are best described as communities of individuals or as holobionts (selective units of hosts plus their microbes). Recent reports that assortative mating of hosts by diet can be mediated by commensal gut microbes have attracted interest as a potential route to host reproductive isolation (RI). Here we discuss logical problems with this line of argument. We briefly review how microbes can affect host mating preferences and evaluate recent findings from fruitflies. Endosymbionts can potentially influence host RI given stable and recurrent co-association of hosts and microbes over evolutionary time. However, observations of co-occurrence of microbes and hosts are ripe for misinterpretation and such associations will rarely represent a meaningful holobiont. A framework in which hosts and their microbes are independent evolutionary units provides the only satisfactory explanation for the observed range of effects and associations