High Precision Mass Measurements in Ψ\Psi and Υ\Upsilon Families Revisited

High precision mass measurements in $\Psi$ and $\Upsilon$ families performed in 1980-1984 at the VEPP-4 collider with OLYA and MD-1 detectors are revisited. The corrections for the new value of the electron mass are presented. The effect of the updated radiative corrections has been calculated for the $J/\Psi(1S)$ and $\Psi(2S)$ mass measurements.Comment: 5 pages, 1 table, submitted to Phys. Lett.

Framing Homeless Policy: Reducing Cash Aid as a Compassionate Solution

In 2002, Care Not Cash/Proposition N was introduced to respond to public concern over San Francisco’s chronic homeless epidemic. The controversial initiative, which significantly reduced General Assistance (cash aid) to unhoused people, diverted funds to direct services such as shelter, food, medical assistance, and substance abuse programs. To investigate the underlying attitudes and beliefs that framed homelessness and the Care Not Cash policy in the months leading up to the citywide vote articles from the San Francisco Chronicle were analyzed. Of particular interest was assessing the prevalence of individualistic framing, constructions of dependency, and the problems Care Not Cash was presented as solving. Our analysis found that homelessness was framed as a threat to businesses, tourism, and residents of San Francisco and welfare as enabling deviant behavior (e.g., substance abuse) among people experiencing homelessness. Similar to federal welfare reform, Care Not Cash was portrayed as a compassionate solution that would both solve the problem of homelessness and address problematic behaviors associated with people who are unhoused (Stryker & Wald, 2009). Implications for economic justice are discussed.Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/147013/1/asap12156_am.pdfhttps://deepblue.lib.umich.edu/bitstream/2027.42/147013/2/asap12156.pd

Chagas' disease: an update on immune mechanisms and therapeutic strategies

The final decade of the 20th century was marked by an alarming resurgence in infectious diseases caused by tropical parasites belonging to the kinetoplastid protozoan order. Among the pathogenic trypanosomatids, some species are of particular interest due to their medical importance. These species include the agent responsible for Chagas' disease, Trypanosoma cruzi. Approximately 8 to 10 million people are infected in the Americas, and approximately 40 million are at risk. in the present review, we discuss in detail the immune mechanisms elicited during infection by T. cruzi and the effects of chemotherapy in controlling parasite proliferation and on the host immune system.Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq)Instituto Nacional de Biologia Estrutural e QuImica Medicinal em Doencas Infecciosas (INBEQMeDI)Univ São Paulo, Inst Biomed Sci, Dept Parasitol, São Paulo, BrazilMackenzie Presbeterian Univ, Ctr Biomol Sci & Hlth, São Paulo, BrazilNatl Univ Rosario, Sch Med Sci, Inst Immunol, Rosario, Santa Fe, ArgentinaCSIC, Inst Parasitol & Biomed Lopez Neyra, Granada, SpainUniversidade Federal de São Paulo, Dept Microbiol Immunol & Parasitol, São Paulo, BrazilUniversidade Federal de São Paulo, Dept Microbiol Immunol & Parasitol, São Paulo, BrazilFAPESP: 08/57596-4FAPESP: 07/08648-9CNPq: 473906/2008-2Web of Scienc

Quantitative evaluation of sperm in men, based on an interval scale

Modern methods of estimation spermogram are quite difficult and highly subjective. Were analyzed spermogram 215 men aged 20 to 46 years (mean age 29,7 ± 2,4 years). The analysis spermogram were selected 5 out of 21 key indicators of ejaculate that affect fertility: the total number, motility, viability, morphology of sperm, ejaculate volume. Based on these data the interval scale, which allows to quantify the sperm. Obtained as a result of an integral index is a reflection of pathological semen analysis based on deviations from the “ideal norm”, that allows to evaluate different sperm, and to evaluate the effectiveness of treatment, as with the use of conservative methods, and various options for surgical intervention

Human colon cancer cell lines show a diverse pattern of nitric oxide synthase gene expression and nitric oxide generation.

A panel of human colonic adenocarcinoma cell lines was examined both for expression of mRNAs of the nitric oxide synthase (NOS) gene family and for evidence of enzymic activity based on citrulline and nitrite (NO2-) formation. Reverse transcription-polymerase chain reaction (RT-PCR), revealed that all lines (SW480, SW620, DLD-1 and WiDr) expressed mRNA for the Ca(2+)-dependent endothelial (e)NOS, while SW480 cells also expressed the Ca(2+)-dependent neuronal (n)NOS. The mRNA for the Ca(2+)-independent inducible (i)NOS was expressed both by cytokine-stimulated and by unstimulated SW480, SW620 and DLD-1 cells, but none was seen at any time in the WiDr cells. There was, however, little correlation between mRNA expression and enzymic activity based on citrulline and NO2- formation. Thus none of the cell lines exhibited measurable Ca(2+)-dependent NOS activity, while Ca(2+)-independent NOS activity was seen in all but the WiDr cells. Furthermore, DLD-1 cells generated citrulline with resultant NO2- formation only after stimulation with lipopolysaccharide (LPS) and/or cytokines, while SW480 and SW620 did so constitutively. Thus RT-PCR studies indicate that tumour cells of similar epithelial origin display a diverse pattern of NOS gene family expression, and parallel biochemical studies clearly indicate that such expression does not always result in measurable enzymic activity leading to the generation of NO

Design and Creative Methods as a Practice of Liminality in Community-Academic Research Projects

This paper aims to explore the types of spaces and experiences that are created by design and creative practices. More specifically, it focuses on how design and creative practices can engender transformations in the mindset, knowledge, emotions and social relations of people who participate in such practices. To do this, the paper investigates the concepts of liminality and liminal spaces, and the relationships between design/creative methods and liminal spaces using insights from four case studies. The results reveal that design and creative practices may create liminal spaces in many ways, such as neutralizing the working environments, encouraging people to experiment with new ideas and helping them express themselves more freely

Preliminary results from the CMD-2 detector

A new general-purpose detector CMD-2 (calorimetric magnetic detector has started experiments at the upgraded e{sup {plus}}e{sup {minus}} collider VEPP-2M (collider for electron-positron beams) at Novosibirsk. During early runs an integrated luminosity of about 400 inverse nanobarns has been collected in the center of mass energy range 400{endash}1030 MeV