Morphological and hemodynamical alterations in brachial artery and cephalic vein. An image‐based study for preoperative assessment for vascular access creation

The current study aims to computationally evaluate the effect of right upper arm position on the geometric and hemodynamic characteristics of the brachial artery (BA) and cephalic vein (CV) and, furthermore, to present in detail the methodology to characterise morphological and hemodynamical healthy vessels. Ten healthy volunteers were analysed in two configurations, the supine (S) and the prone (P) position. Lumen 3D surface models were constructed from images acquired from a non-contrast MRI sequence. Then, the models were used to numerically compute the physiological range of geometric (n = 10) and hemodynamic (n = 3) parameters in the BA and CV. Geometric parameters such as curvature and tortuosity, and hemodynamic parameters based on wall shear stress (WSS) metrics were calculated with the use of computational fluid dynamics. Our results highlight that changes in arm position had a greater impact on WSS metrics of the BA by altering the mean and maximum blood flow rate of the vessel. Whereas, curvature and tortuosity were found not to be significantly different between positions. Inter-variability was associated with antegrade and retrograde flow in BA, and antegrade flow in CV. Shear stress was low and oscillatory shear forces were negligible. This data suggests that deviations from this state may contribute to the risk of accelerated intimal hyperplasia of the vein in arteriovenous fistulas. Therefore, preoperative conditions coupled with post-operative longitudinal data will aid the identification of such relationships

Enhancing volunteer engagement to achieve desirable outcomes: what can non-profit employers do?

Abstract Engagement is a positive psychological state that is linked with a range of beneficial individual and organizational outcomes. However, the factors associated with volunteer engagement have rarely been examined. Data from 1064 volunteers of a wildlife charity in the United Kingdom revealed that both task- and emotion-oriented organizational support were positively related to volunteer engagement, and volunteer engagement was positively related to volunteer happiness and perceived social worth and negatively related to intent to leave the voluntary organization. Consistent with theory, engagement acted as a mediator between these factors. The implications for future research and the relevance of the findings for voluntary organizations are discussed

Use of compositional analyis to show estimated changes in cardiometabolic health by reallocating time to light intensity physical activity in older adults.

All physical activity (PA) behaviours undertaken over the day, including sleep, sedentary time, standing time, light-intensity PA (LIPA) and moderate-to-vigorous PA (MVPA) have the potential to influence cardiometabolic health. Since these behaviours are mutually exclusive, standard statistical approaches are unable to account for the impact on time spent in other behaviours. Objective By employing a compositional data analysis (CoDA) approach, this study examined the associations of objectively measured time spent in sleep, sedentary time, standing time, LIPA and MVPA over a 24-h day on markers of cardiometabolic health in older adults. Methods Participants (n =366; 64.6 years [5.3]; 46% female) from the Mitchelstown Cohort Rescreen Study provided meas- ures of body composition, blood lipid and markers of glucose control. An activPAL3 Micro was used to obtain objective measures of sleep, sedentary time, standing time, LIPA and MVPA, using a 7-day continuous wear protocol. Regression analysis, using geometric means derived from CoDA (based on isometric log-ratio transformed data), was used to examine the relationship between the aforementioned behaviours and markers of cardiometabolic health. Results Standing time and LIPA showed diverging associations with markers of body composition. Body mass index (BMI), body mass and fat mass were negatively associated with LIPA (all p <0.05) and positively associated with standing time (all p <0.05). Sedentary time was also associated with higher BMI (p <0.05). No associations between blood markers and any PA behaviours were observed, except for triglycerides, which were negatively associated with standing time (p < 0.05). Reallocating 30 min from sleep, sedentary time or standing time, to LIPA, was associated with significant decreases in BMI, body fat and fat mass. Conclusion This is the first study to employ CoDA in older adults that has accounted for sleep, sedentary time, standing time, LIPA and MVPA in a 24-h cycle. The findings support engagement in LIPA to improve body composition in older adults. Increased standing time was associated with higher levels of adiposity, with increased LIPA associated with reduced adiposity; therefore, these findings indicate that replacing standing time with LIPA is a strategy to lower adiposity.ye

Drilling their own graves:How the European oil and gas supermajors avoid sustainability tensions through mythmaking

This study explores how paradoxical tensions between economic growth and environmental protection are avoided through organizational mythmaking. By examining the European oil and gas supermajors’ ‘‘CEOspeak’’ about climate change, we show how mythmaking facilitates the disregarding, diverting, and/or displacing of sustainability tensions. In doing so, our findings further illustrate how certain defensive responses are employed: (1) regression, or retreating to the comforts of past familiarities, (2) fantasy, or escaping the harsh reality that fossil fuels and climate change are indeed irreconcilable, and (3) projecting, or shifting blame to external actors for failing to address climate change. By highlighting the discursive effects of enacting these responses, we illustrate how the European oil and gas supermajors self-determine their inability to substantively address the complexities of climate change. We thus argue that defensive responses are not merely a form of mismanagement as the paradox and corporate sustainability literature commonly suggests, but a strategic resource that poses serious ethical concerns given the imminent danger of issues such as climate change

Duty to God/my Dharma/Allah/Waheguru: diverse youthful religiosities and the politics and performance of informal worship

This article was published in the journal, Social and Cultural Geography [© Taylor & Francis] and the definitive version is available at: http://dx.doi.org/10.1080/14649365.2012.698749This paper draws on a case study of the Scout Movement in the UK to explore the everyday, informal expressions of ‘worship’ by young people that occur outside of ‘designated’ religious spaces and the politics of these performances over time. In analysing the explicit geographies of how young people in UK scouting perform their ‘duty to God’ (or Dharma and so forth), it is argued that a more expanded concept of everyday and embodied worship is needed. This paper also attends to recent calls for more critical historical geographies of religion, drawing on archival data to examine the organisation's relationship with religion over time and in doing so contributes new insights into the production of youthful religiosities and re-thinking their designated domains

All-flavor constraints on nonstandard neutrino interactions and generalized matter potential with three years of IceCube DeepCore data

We report constraints on nonstandard neutrino interactions (NSI) from the observation of atmospheric neutrinos with IceCube, limiting all individual coupling strengths from a single dataset. Furthermore, IceCube is the first experiment to constrain flavor-violating and nonuniversal couplings simultaneously. Hypothetical NSI are generically expected to arise due to the exchange of a new heavy mediator particle. Neutrinos propagating in matter scatter off fermions in the forward direction with negligible momentum transfer. Hence the study of the matter effect on neutrinos propagating in the Earth is sensitive to NSI independently of the energy scale of new physics. We present constraints on NSI obtained with an all-flavor event sample of atmospheric neutrinos based on three years of IceCube DeepCore data. The analysis uses neutrinos arriving from all directions, with reconstructed energies between 5.6 GeV and 100 GeV. We report constraints on the individual NSI coupling strengths considered singly, allowing for complex phases in the case of flavor-violating couplings. This demonstrates that IceCube is sensitive to the full NSI flavor structure at a level competitive with limits from the global analysis of all other experiments. In addition, we investigate a generalized matter potential, whose overall scale and flavor structure are also constrained

Design of a Robust Fiber Optic Communications System for Future IceCube Detectors

In this work we discuss ongoing development of a hybrid fiber/copper data and timing infrastructure for the future IceCube-Gen2 detector. The IceCube Neutrino Observatory is a kilometer-scale detector operating with 86 strings of modules. These modules communicate utilizing a custom protocol to mitigate the signaling challenges of long distance copper cables. Moving past the limitations of a copper-based backbone will allow larger future IceCube detectors with extremely precise timing and a large margin of excess throughput to accommodate innovative future modules. To this end, the upcoming IceCube Upgrade offers an opportunity to deploy a pathfinder for the new fiber optic infrastructure, called the Fiber Test System. This design draws on experience from AMANDA and IceCube and incorporates recently matured technologies such as ruggedized fibers and White Rabbit timing to deliver robust and high-performance data and timing transfer

Density of GeV Muons Measured with IceTop

We present a measurement of the density of GeV muons in near-vertical air showers using three years of data recorded by the IceTop array at the South Pole. We derive the muon densities as functions of energy at reference distances of 600 m and 800 m for primary energies between 2.5 PeV and 40 PeV and between 9 PeV and 120 PeV, respectively, at an atmospheric depth of about 690g/cm$^2$. The measurements are consistent with the predicted muon densities obtained from Sibyll 2.1 assuming any physically reasonable cosmic ray flux model. However, comparison to the post-LHC models QGSJet-II.04 and EPOS-LHC shows that the post-LHC models yield a higher muon density than predicted by Sibyll 2.1 and are in tension with the experimental data for air shower energies between 2.5 PeV and 120 PeV

Design, performance, and analysis of a measurement of optical properties of antarctic ice below 400 nm

The IceCube Neutrino Observatory, located at the geographic South Pole, is the world\u27s largest neutrino telescope, instrumenting 1 km$^3$ of Antarctic ice with 5160 photosensors to detect Cherenkov light. For the IceCube Upgrade, to be deployed during the 2022-23 polar field season, and the enlarged detector IceCube-Gen2 several new optical sensor designs are under development. One of these optical sensors, the Wavelength-shifting Optical Module (WOM), uses wavelength-shifting and light-guiding techniques to measure Cherenkov photons in the UV range from 250 nm to 380 nm. In order to understand the potential gains from this new technology, a measurement of the scattering and absorption lengths of UV light was performed in the SPICEcore borehole at the South Pole during the winter seasons of 2018/2019 and 2019/2020. For this purpose, a calibration device with a UV light source and a detector using the wavelength shifting technology was developed. We present the design of the developed calibration device, its performance during the measurement campaigns, and the comparison of data to a Monte Carlo simulation