Sistema HW-SW de telerehabilitación y telemedicina para pacientes Epoc con hiperinsuflación pulmonar

La enfermedad pulmonar obstructiva crónica es la cuarta causa de muerte en el mundo. Gran parte de estos enfermos no están diagnosticados y a medida que avanza la enfermedad empiezan a aparecer dificultades en la respiración y cambios en la fisiología pulmonar. Entre estos cambios está la hiperinsuflación, los pacientes hiperinsuflados retienen aire en los pulmones. Por lo tanto, estos pacientes requieren de un seguimiento y necesitan hacer ejercicios específicos con dispositivos PEP (Presión Espiratoria Postiva) para expulsar este aire. En este proyecto se implementa un sistema que comprenda la función de espirometría y la función de telerehabilitación. Para esto se desarrolla por un lado una aplicación móvil que será la interfaz gráfica y el motor de cálculo, por otro se diseña un espirómetro de turbina que mediante bluetooth envía la velocidad del aire exhalado a la aplicación, y por último dos boquillas intercambiables, una para las pruebas de espirometría y otra que será la boquilla PEP para ejercicios de rehabilitación. Para la boquilla PEP, la cual integra la misma turbina para poder contar revoluciones, se diseñará un juego que mediante estimulación visual avisará al paciente de cuando espira demasiado fuerte o demasiado lento, ayudando así a que los ejercicios se hagan correctamente. Para la boquilla de espirometría, se calcularán la FVC, la FEV1, el Índice de Tiffenau y la curva flujo volumen y se almacenarán los resultados para verlos gráficamente en función del tiempo. Con este proyecto, se pretende dar facilidades y solución a las personas que padecen esta patología, cuyas necesidades requieren de ayuda externa de centros médicos para realizar el seguimiento de su enfermedad y llevar a cabo la rehabilitación, de este modo, se ofrece la posibilidad de hacerlo desde casa y con un control equitativo al que podría dar el servicio técnico de un centro médico.Chronic obstructive pulmonary disease is the fourth leading cause of death in the world. Many of these patients are not diagnosed and as the disease progresses, breathing difficulties and changes in pulmonary physiology begin to appear. Among these changes is hyperinflation, hyperinflation patients retain air in the lungs. Therefore, these patients require follow-up and need to do specific exercises with PEP (Positive Expiratory Pressure) devices to expel this air. In this project we want to implement a system that includes the function of spirometry (calculation of lung function) and telerehabilitation function. For this reason, It is developed on the one hand a mobile application that will be the graphical interface and computer brain, on the other hand is designed a turbine spirometer that by bluetooth sends the velocity of the exhaled air to the application, and finally two replaceable nozzles, one for spirometry tests and another that will be the PEP nozzle for rehabilitation exercises. For the PEP nozzle, which integrates the same turbine to be able to count revolutions, a game will be designed that, through visual stimulation, will alert the patient when exhales too hard or too slow, thus helping the exercises to be performed correctly. For the spirometry nozzle, the FVC, FEV1, Tiffenau Index and volume flow curve will be calculated, and the results stored for graphing as a function of time. With this project, it is intended to provide facilities and solutions to people suffering from this pathology, whose needs require external help from medical centers to follow up their disease and carry out rehabilitation, thereby offering the possibility of do it from home and with equitable control that could give the technical service of a medical center.Universidad de Sevilla. TEP- 108: Robótica y Tecnología de Computadore

Intergenerational struggles and technological dramas of the neobakala music scene

In late modernity, Western societies undergo profound processes of change that lead to tensions between different social actors, which sometimes occur in intergenerational terms. This article explores these tensions in the field of music through the neobakala scene, which is composed of adults who have created a nostalgic discourse to establish a hierarchy with other musical scenes created by youngsters. The concepts of nostalgia and generation, therefore, will be key in articulating this text but both will be critically approximated, since the two assume a presence of memory in their constitution (that is not always backed by evidence). In this sense, this article, which also explores the past of the neobakala scene, claims memory as a field on its own, differentiated from nostalgia and as a source of criticism of it. On the other hand, in the analysis of this nostalgia, the neobakala scene and the same intergenerational struggles that occur in this late modernity, this article will pay special attention to the role of technological changes. To this end, the article will resort to the concept of remediation and, above all, that of "technological drama", which will allow us to observe a process of reintegration in which the neobakala subversive past ends up aligning itself with power in a context of expansion of digital technologies

Reducing C-terminal truncation mitigates synucleinopathy and neurodegeneration in a transgenic model of multiple system atrophy

Multiple system atrophy (MSA) is a sporadic orphan neurodegenerative disorder. No treatment is currently available to slow down the aggressive neurodegenerative process, and patients die within a few years after disease onset. The cytopathological hallmark of MSA is the accumulation of alpha-synuclein (α-syn) aggregates in affected oligodendrocytes. Several studies point to α-syn oligomerization and aggregation as a mediator of neurotoxicity in synucleinopathies including MSA. C-terminal truncation by the inflammatory protease caspase-1 has recently been implicated in the mechanisms that promote aggregation of α-syn in vitro and in neuronal cell models of α-syn toxicity. We present here an in vivo proof of concept of the ability of the caspase-1 inhibitor prodrug VX-765 to mitigate α-syn pathology and to mediate neuroprotection in proteolipid protein α-syn (PLP-SYN) mice, a transgenic mouse model of MSA. PLP-SYN and age-matched wild-type mice were treated for a period of 11 wk with VX-765 or placebo. VX-765 prevented motor deficits in PLP-SYN mice compared with placebo controls. More importantly, VX-765 was able to limit the progressive toxicity of α-syn aggregation by reducing its load in the striatum of PLP-SYN mice. Not only did VX-765 reduce truncated α-syn, but it also decreased its monomeric and oligomeric forms. Finally, VX-765 showed neuroprotective effects by preserving tyrosine hydroxylase-positive neurons in the substantia nigra of PLP-SYN mice. In conclusion, our results suggest that VX-765, a drug that was well tolerated in a 6 wk-long phase II trial in patients with epilepsy, is a promising candidate to achieve disease modification in synucleinopathies by limiting α-syn accumulation

Making a difference: One teacher's journey as a mentor

The focus of this work was a mentor-protege relationship that developed over the course of several months between a five year veteran teacher, myself, and Olivia, who was hired for her first year to teach Science in Kindergarten, First, Fourth and Fifth grades. It began as help to plan the First grade lessons only, but over the course of ten meetings it became assistance with planning, teaching strategies, classroom management and advice for all grade levels. Interactions included three observations of her teaching (once in First grade and twice in Kindergarten), teaching a model lesson for a First grade class at her school, and acting as a critical friend and confidant. Having reflected on the data collected and our time together, the following findings have emerged. 1. Teacher attrition is an enormous problem facing first year teachers. 2. A successful mentor-protege relationship requires certain conditions. 3. The experience of acting as a mentor is invaluable to the veteran teacher, offering opportunities for growth and self-reflection. 4. Time and space for teaching science in the elementary classroom is limited, and teachers often feel unqualified to do so. Key Words: mentor, teacher attrition, critical frien

Entre héroes, patriarcas y monstruos: las máscaras masculinas del bacalao madrileño

Este artículo toma como referencia el modelo de máscaras masculinas de Gil Calvo (2006) para visibilizar y explicar, a partir de datos etnográficos, las masculinidades del bacalao madrileño en todas sus versiones, presentes y pasadas. Esto supone abordar, desde esta perspectiva que incluya esta variable de género, tanto las tres culturas juveniles (Feixa, 1998) que constituyeron este fenómeno en los años ochenta y noventa del siglo XX —bacalas, bakalas y vakalas (Leste, 2020a)— como la escena musical (Straw, 1991) neobakala que ha creado en el presente un patrimonio cultural (Jiménez-Esquinas, 2017). Este artículo, además, analiza la ritualidad de estas masculinidades a partir del trabajo de Turner (1982), algo que permite ver cómo estos sujetos las afianzan, al mismo tiempo que lidian con las cargas percibidas de las mismas

ANALISIS STRATEGI KOMUNIKASI PERSUASIF , PERSONAL SELLING, MARKETING COMMUNICATION, DAN KOMUNIKASI INTERPERSONAL AGEN ASURANSI SYARI’AH DALAM MENINGKATKAN PENJUALAN POLIS PRODUK ASURANSI SYARI’AH (STUDI KASUS PADA PT. ASURANSI UMUM BUMIPUTERA MUDA 1967 UNIT SYARI’AH BANDAR LAMPUNG)

ABSTRAK Penelitian ini berjudul Analisis Strategi Komunikasi Persuasif, Personal Selling, Marketing Communication, dan Komunikasi Interpersonal Agen Asuransi Syari’ah dalam meningkatkan Penjualan Polis Produk Asuransi Syari’ah (Studi Kasus pada PT. Asuransi Umum Bumiputera Muda 1967 Unit Syari’ah Bandar Lampung). Penelitian ini bertujuan untuk mengetahui strategi komunikasi persuasif, personal selling, marketing communication, dan komunikasi interpersonal yang digunakan para agen asuransi dalam membujuk calon nasabah untuk meningkatkan penjualan polis produk asuransi syari’ah . Dalam penelitian ini, studi yang digunakan adalah studi deskriptif kualitatif yang dapat menggambarkan dan mendeskripsikan peranan komunikasi persuasif, personal selling, marketing communication, dan komunikasi interpersonal yang dilakukan agen asuransi dalam membujuk calon nasabah membeli produk asuransi. Fokus penelitian dalam skripsi ini adalah bagaimana strategi komunikasi persuasif, personal selling, marketing communication dan komunikasi interpersonal agen asuransi syari’ah dalam meningkatkan penjualan polis produk syari’ah. Adapun tujuan penelitian dalam skripsi ini adalah untuk mengetahui bagaimana strategi komunikasi persuasif, personal selling, marketing communication dan komunikasi interpersonal agen asuransi syari’ah dalam meningkatkan penjualan polis produk asuransi syari’ah pada PT Asuransi umum bumiputera muda 1967 unit syari’ah Bandar Lampung. Penelitian ini menggunakan metode penelitian kualitatif. Jenis penelitian yang digunakan dalam penelitian skripsi ini adalah penelitian lapangan. Sumber data yang diperoleh yaitu data primer dan data sekunder. Teknik pengumpulan data pada penelitian ini adalah wawancara, quesioner dan dokumentasi. Sedangkan, teknik analisis data yang digunakan adalah reduksi data, penyajian data, analisis data dan penarikan kesimpulan. Adapun hasil penelitian adalah dari keempat strategi tersebut semua punya peluang dan tingkat keberhasilan yang saling berkaitan, iv jadi tidak ada patokan satu cara mana yang paling berhasil, jadi semua strategi itu saling berkaitan erat satu sama lain dan saling menaungi. Dan semua startegi yang diterapkan sama-sama berperan penting. Dari keempat strategi tersebut tidak mungkin 100% dapat dijalankan penuh, karena tentu masih banyak kendala yang terjadi dan dapat disimpulkan 70-80% tingkat keberhasilannya. Kata Kunci: Komunikasi Persuasif, Personal Selling, Marketing Communication, Komunikasi Interpersonal. v ABSTRACT This research is entitled Analysis of Persuasive Communication Strategies, Personal Selling, Marketing Communication, and Interpersonal Communication of Syari'ah Insurance Agents in Increasing Sales of Syari'ah Insurance Products Policies (Case Study at PT. Bumiputera Muda 1967 General Insurance Sharia Unit Bandar Lampung). This study aims to determine the persuasive communication strategies, personal selling, marketing communication, and interpersonal communication used by insurance agents in persuading prospective customers to increase sales of sharia insurance product policies. In this study, the study used is a qualitative descriptive study that can describe and describe the role of persuasive communication, personal selling, marketing communication, and interpersonal communication by insurance agents in persuading prospective customers to buy insurance products. The focus of the research in this thesis is how persuasive communication strategies, personal selling, marketing communication and interpersonal communication of sharia insurance agents increase sales of sharia product policies. The purpose of the research in this thesis is to find out how the strategy of persuasive communication, personal selling, marketing communication and interpersonal communication of sharia insurance agents in increasing sales of sharia insurance product policies at PT Asuransi Umum Bumiputera Muda 1967 sharia unit Bandar Lampung. This study used qualitative research methods. The type of research used in this thesis research is field research. Sources of data obtained are primary data and secondary data. Data collection techniques in this study were interviews, questionnaires and documentation. Meanwhile, the data analysis techniques used are data reduction, data presentation, data analysis and drawing conclusions. The results of the research are that of the four strategies, all of them have interrelated opportunities and success rates, so there is no benchmark which one method is the most successful, so all of these strategies are closely related to each other and shade each other. And vi all the strategies applied equally play an important role. Of the four strategies it is impossible 100% to be fully implemented, because of course there are still many obstacles that occur and it can be concluded that the success rate is 70-80%. Keywords: Persuasive Communication, Personal Selling, Marketing Communication, Interpersonal Communicatio

El poder del amor. Género y desigualdad en cuatro películas románticas contemporáneas

Este artículo explora cómo se distribuye y representa la desigualdad entre los distintos géneros establecidos a través del amor en un contexto capitalista. Con este fin, se analizan cuatro películas románticas contemporáneas que modelizan un amor heterosexual en el que hombres y mujeres son representados dentro de unas categorías algo variables, que dan lugar a masculinidades y feminidades diferentes, pero cuyo sentido de la interacción siempre es el mismo, reservando para la mujer roles o espacios secundarios. Pero este artículo no sólo analiza las desigualdades en la interacción y representación entre los distintos géneros establecidos, sino que, además, trata de analizar, desde una perspectiva freudiana, cómo la desigualdad se establece también en el interior de los distintos personajes representados en función, de nuevo, del género. Todo esto se produce, precisamente, en un contexto en que estos roles y desigualdades se erosionan y, por tanto, la producción y consumo de este tipo de relatos constituye una reafirmación ritual de los valores y principios de ese amor que mantiene para la mujer un papel secundario

Ambivalencias y transformaciones de las fiestas neobakalas

This article ethnographically explores how the neobakala music scene creates ritual and carnivalesque practices to deal with the affective states produced by late capitalism in urban societies. To this end, this study takes as its point of reference the theoretical and methodological proposal of affectivity suggested by Alexandre Surrallés (2005). The article therefore explores the capitalist body and personhood, and identifies its affective states and identity discourses to see how these are projected and reflected. The paper also considers the contributions to the understanding of nostalgia made by Arjun Appadurai (2001) and Sinji Hirai (2009) and finally explores its relations with memory, revealing that, in this case, nostalgia seems to erode memory.Este artículo explora, a partir de fuentes etnográficas, la forma en que los miembros de la escena musical neobakala lidian, mediante prácticas rituales y carnavalescas, con los estados afectivos derivados de la vida urbana en el capitalismo tardío. Con este fin, este trabajo toma como referencia la propuesta teórica y metodológica sobre la afectividad de Alexandre Surrallés (2005 y 2009). En este sentido, este texto se adentra en el cuerpo y la persona capitalista para, a partir de ahí, identificar contextualmente sus estados de ánimo, sus relatos identitarios y los grupos sobre los cuales este relato se despliega y repliega. En este plano afectivo, este trabajo, donde la nostalgia es un aspecto central, también tiene en cuenta otros aportes hechos, de nuevo, desde la antropología, como son los de Appadurai (2001) o Hirai (2009). Por último, el artículo se adentra en las relaciones entre la nostalgia y la memoria y muestra cómo, en este caso, la memoria parece erosionarse por la acción de la nostalgia

La escena nostálgica neobakala: transformación y ritualización musical de la cultura juvenil bakala

Los bakalas fueron una cultura juvenil que apareció en algunos lugares de España, entre ellos Madrid. Después de desaparecer, esta cultura ha sido reformulada de forma nostálgica por los neobakalas madrileños. Este artículo explora, a partir de datos etnográficos y entrevistas en profundidad, la forma en que estos neobakalas han transformado aquella cultura juvenil en una escena musical que ritualiza algunos de los elementos que la compusieron, especialmente sus músicas, produciendo un género musical. Además, este artículo constituye un esfuerzo por matizar ciertas formas de abordar la participación de personas adultas en escenas musicales, cuestionando la aplicabilidad del concepto de “ageing” (Bennet y Hodkinson 2012; Bennet 2013) y de “memoria cultural” (Bennet y Rogers 2016) en este caso de estudio. Por último, el caso de los neobakalas nos llevará a problematizar la forma en que St John (1999, 2011, 2014) analiza la ritualidad de las escenas relacionadas con la música electrónica.The Bakalas were a youth culture that showed up in some Spanish cities, Madrid among them. After disappearing, this culture has been recreated by neobakalas. This article, based on ethnography and in-depth interviews, explores how neobakalas from Madrid have transformed the bakala culture into a music scene that ritualizes some of the features of the bakalas, especially its songs, giving birth to a music genre. Furthermore, the case of bakalas and neobakalas will allow us to question the way Bennet (2012, 2013) has approached music scenes formed by adults. This work therefore interrogates the applicability of the concepts of ageing cultures (Bennet y Hodkinson 2012; Bennet, 2013) and cultural memory for the neobakala scene. The case of neobakalas will also allow us to problematize how St John (1999, 2011, 2014) analyses the ritual practices of the music scenes related to electronic music

Spectro-photometric analysis of galaxy merger remnants with tidal features

1 online resource (xvi, 68 pages) : illustrations (chiefly colour)Includes abstract and appendix.Includes bibliographical references (pages 65-68).We use 21 208 galaxies at redshifts 0.05 < z < 0.45 with images from the Hyper Suprime-Cam Subaru Strategic Program (HSC-SSP) and accompanying spectroscopic observations from the Sloan Digital Sky Survey (SDSS) to study the properties of systems that host features of past mergers: streams and shells. We detect 251 shells and 774 streams through visual classification of the original and filtered galaxy images. We retrieve measurements of stellar mass and stellar population age for 16 936 galaxies from our sample. Galaxies with shells are more massive and older than both featureless galaxies and stream hosts, suggesting that they may be a result of major mergers. We analyse the star formation rates (SFR) for 6738 of our galaxies, derived from reliable measurements of H&alpha; available from the SDSS Legacy Survey. Shell hosts are predominantly among quiescent galaxies while stream hosts span the full range of SFR measurements. We construct diagnostic diagrams for 6778 galaxies to separate star forming galaxies from those that are dominated by Active Galactic Nuclei (AGN). A fraction (10%) of galaxies with streams show evidence of strong AGN activity, which may be a result of material being funnelled into the central region of the host galaxy. In contrast, almost no shell hosts show the presence of strong nuclear activity. We measure the local density in the vicinity of our tidal feature hosts using data from the New York University Value-Added Galaxy Catalog (NYU-VAGC). We find that galaxies with features are, as expected, neither in isolated regions nor in clusters since these environments suppress mergers. We also observe that galaxies with shells tend to be in regions with slightly higher densities than the general population of galaxies. Based on sheer numbers and the distribution of the basic properties of the galaxies, we find that streams can occur in a vast range of galaxy mergers, while the formation of shells needs specific sets of conditions