496 research outputs found
Thermodynamic, transport, and flow properties for the products of methane burned in oxygen-enriched air
Thermodynamic, transport, and flow properties for products of methane burned in oxygen-enriched ai
Experimental results of cooling a 12.5 deg semivertex angle cone by ejection of hydrogen and helium from its apex at mach 7
Cooling of nose cone by ejection of hydrogen and helium from its apex at mach
Patient Perspectives of an Intensive Comprehensive Aphasia Program for Stroke Survivors
Individuals with aphasia who participate in intensive post-stroke language rehabilitation programs make a variety of significant investments. Investments involve commitment across many domains including: time, finance, family participation, temporary relocation, as well as cognitive, physical, and emotional exertion. While intensive aphasia programs and intensive comprehensive aphasia programs (ICAPs) are becoming increasingly prevalent across health care settings (Rodriguez et al., 2017; Rose, et al 2013), and language-based and psychosocial outcomes are beginning to be reported in the literature (e.g., Babbitt, Worrall, & Cherney, 2015; Hoover, Caplan, Waters, & Carney, 2017), patient perspectives have yet to be explored. As health care moves towards patient centered care (Robinson et al., 2008), persons with aphasia (PWA)’s perspectives of their rehabilitation experience should inform current research and intervention approaches (e.g., Barrett, 2010).
The purpose of this qualitative study is to examine patient perspectives on the experience of participating in an intensive comprehensive aphasia program (ICAP), specifically the Big Sky Aphasia Program (BSAP) at University of Montana. Investigating what it is like for a person with aphasia (PWA) to participate in an ICAP will contribute to the exploration of the worthwhileness of the ICAP model. The primary research question of this study was: “what is it like to be a PWA in an ICAP?”
Investigators conducted nine, face-to-face, semi-structured interviews to collect narrative data from PWA who participated in the BSAP ICAP. The researchers asked the participants to describe their experiences and perspectives of the ICAP All interviews were audiovisually recorded and transcribed from the video recordings. Spoken production was transcribed verbatim and meaningful non-verbal communication (e.g., pointing) was also documented in the transcripts. Both researchers present during interviews took field notes on topics interviewees emphasized as important. Transcripts and field notes will be analyzed to create codes (i.e., phrases with keywords that represent significant concepts in participants’ experiences).
Data will be analyzed for themes and conclusions will be made about participants’ experiences in the BSAP ICAP. Implications of these perspectives for future ICAP implementation and research will be discussed
An Ethnographic Inquiry: Contemporary Language Ideologies of American Sign Language
Historically, American Sign Language (an aspect of Deaf culture) has been rendered invisible in mainstream hearing society. Today, ASL’s popularity is evidenced in an ethnolinguistic renaissance; more second language learners pursue an interest in ASL than ever before. Nonetheless, Deaf and hearing people alike express concern about ASL’s place in hearing culture. This qualitative study engages ethnographic methods of participant observation and semi-structured interviewing as well as popular media analysis to understand language ideologies (ideas and objectives concerning roles of language in society) hearing and Deaf Signers hold about motivations and practices of other hearing Signers. Although most hearing ASLers identify as apolitical students genuinely seeking to build bridges between disparate communities, I argue that ASLers are most concerned with hearing Signers’ colonization of the language through commoditization and cultural appropriation
Altered Serum IgG Levels to a-Synuclein in Dementia with Lewy Bodies and Alzheimer’s Disease.
Natural self-reactive antibodies in the peripheral blood may play a considerable role in the control of potentially toxic proteins that may otherwise accumulate in the aging brain. The significance of serum antibodies reactive against asynuclein is not well known. We explored serum IgG levels to monomeric a-synuclein in dementia with Lewy bodies (DLB) and Alzheimer’s disease (AD) with a novel and validated highly sensitive ELISA assay. Antibody levels revealed stark differences in patients compared to healthy subjects and were dependent on diagnosis, disease duration and age. Anti-asynuclein IgG levels were increased in both patient groups, but in early DLB to a much greater extent than in AD. Increased antibody levels were most evident in younger patients, while with advanced age relatively low levels were observed, similar to healthy individuals, exhibiting stable antibody levels independent of age. Our data show the presence of differentially altered IgG levels against a-synuclein in DLB and AD, which may relate to a disturbed a-synuclein homeostasis triggered by the disease process. These observations may foster the development of novel, possibly preclinical biomarkers and immunotherapeutic strategies that target a-synuclein in neurodegenerative disease.Fil: Koehler, Niklas. Department of Psychiatry and Psychotherapy. EBERHARD-KARLS-UNIVERSITY;Fil: Stransky, Elke. Department of Psychiatry and Psychotherapy. EBERHARD-KARLS-UNIVERSITY;Fil: Shing, Mona. Department of Psychiatry and Psychotherapy. EBERHARD-KARLS-UNIVERSITY;Fil: Gaertner, Susanne. Department of Psychiatry and Psychotherapy, EBERHARD-KARLS-UNIVERSITY;Fil: Meyer, Mirjam. Department of Psychiatry and Psychotherapy. EBERHARD-KARLS-UNIVERSITY;Fil: Schreitmueller, Brigitte. Department of Psychiatry and Psychotherapy. EBERHARD-KARLS-UNIVERSITY;Fil: Leyhe, Thomas. Department of Psychiatry and Psychotherapy. EBERHARD-KARLS-UNIVERSITY;Fil: Laske, Cristoph. Department of Psychiatry and Psychotherapy. EBERHARD-KARLS-UNIVERSITY;Fil: Maetzler, Walter. Department of Neurodegeneration. HERTIE INSTITUTE FOR CLINICAL BRAIN RESEARCH;Fil: Kahle, Philipp. FUNCTIONAL NEUROGENETICS. HERTIE INSTITUTE FOR CLINICAL;Fil: Celej, Maria Soleda. MAX-PLANCK-INSTITUTE FOR BIOPHYSICAL CHEMISTRY; Consejo Nacional de Invest.cientif.y Tecnicas. Centro Cientifico Tecnol.conicet - Cordoba. Centro de Invest.en Qca.biol.de Cordoba (p);Fil: Jovin, Thomas M.. MAX-PLANCK-INSTITUTE FOR BIOPHYSICAL CHEMISTRY;Fil: Fallgatter, Andreas. Department of Psychiatry and Psychotherapy. EBERHARD-KARLS-UNIVERSITY;Fil: Batra, Anil. Department of Psychiatry and Psychotherapy. EBERHARD-KARLS-UNIVERSITY;Fil: Buchkremer, Gherard. Department of Psychiatry and Psychotherapy. EBERHARD-KARLS-UNIVERSITY;Fil: Schott, Klauss. Department of Psychiatry and Psychotherapy. EBERHARD-KARLS-UNIVERSITY;Fil: Richartz-Salzburger, Elke. Department of Psychiatry and Psychotherapy. EBERHARD-KARLS-UNIVERSITY
Search for the Lepton Flavor Violation Process at BESIII
We search for the lepton-flavor-violating decay of the into an
electron and a muon using events
collected with the BESIII detector at the BEPCII collider. Four candidate
events are found in the signal region, consistent with background expectations.
An upper limit on the branching fraction of (90% C.L.) is obtained
Observation of at BESIII
Using events collected with the BESIII detector
at the BEPCII storage rings, we observe for the first time the process
,
with a significance of ( including systematic
uncertainties). The product branching fraction of is measured to be
, where the first error is statistical and the
second is systematic. This measurement provides information on the
production near threshold coupling to and improves the understanding
of the dynamics of decays to four body processes.Comment: 8 pages, 7 figure
Search for C-parity violation in and
Using events recorded in
collisions at 3.686 GeV with the BESIII at the BEPCII collider, we
present searches for C-parity violation in and decays via . No significant
signals are observed in either channel. Upper limits on the branching fractions
are set to be and
at the 90\%
confidence level. The former is one order of magnitude more stringent than the
previous upper limit, and the latter represents the first limit on this decay
channel.Comment: 7 pages, 2 figure
Impairment in Proverb Interpretation as an Executive Function Deficit in Patients with Amnestic Mild Cognitive Impairment and Early Alzheimer's Disease
Background/Aims: Proverb interpretation is assumed to reflect executive functions. We hypothesized that proverb interpretation is impaired in patients with amnestic mild cognitive impairment (aMCI) diagnosed as single-domain impairment by common neuropsychological testing. Methods: We compared performance in a proverb interpretation test in single-domain aMCI patients and patients with early Alzheimer’s disease (EAD). Results: The groups with aMCI and EAD performed significantly worse than healthy controls. Both patient groups gave concrete answers with a similar frequency. However, patients with EAD tended to give senseless answers more frequently. Conclusions: Our data suggest that in patients diagnosed as single-domain aMCI, deterioration of executive functions is detectable with subtle and appropriate neuropsychological testing. Implementation of these procedures may improve the early prediction of AD
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