1,577 research outputs found
Semiquantum key distribution with secure delegated quantum computation
Semiquantum key distribution allows a quantum party to share a random key
with a "classical" party who only can prepare and measure qubits in the
computational basis or reorder some qubits when he has access to a quantum
channel. In this work, we present a protocol where a secret key can be
established between a quantum user and an almost classical user who only needs
the quantum ability to access quantum channels, by securely delegating quantum
computation to a quantum server. We show the proposed protocol is robust even
when the delegated quantum server is a powerful adversary, and is
experimentally feasible with current technology. As one party of our protocol
is the most quantum-resource efficient, it can be more practical and
significantly widen the applicability scope of quantum key distribution.Comment: 7 pages, 2 figure
What Drives Home Market Advantage?
In the automobile industry, as in many tradable goods markets, firms earn their highest market share within their domestic market. This home market advantage persists despite substantial integration of international markets during the past several decades. The goal of this paper is to quantify the supply- and demand-driven sources of the home market advantage and to understand their implications for international trade and investment. Building on the random coefficients demand model developed by Berry, Levinsohn, and Pakes (1995), we estimate demand and supply in the automobile industry for nine countries across three continents, allowing for unobserved taste and cost variation at the car model and market levels. While trade and foreign production costs as well as taste heterogeneity matter for market outcomes, we find that preference for domestic brands is the single most important driver of home market advantage - even after controlling for brand histories and dealer networks
HDAC 1 and 6 modulate cell invasion and migration in clear cell renal cell carcinoma
Indexación: Web of ScienceBackground: Class I histone deacetylases (HDACs) have been reported to be overexpressed in clear cell renal cell carcinoma (ccRCC), whereas the expression of class II HDACs is unknown.
Methods: Four isogenic cell lines C2/C2VHL and 786-O/786-OVHL with differential VHL expression are used in our studies. Cobalt chloride is used to mimic hypoxia in vitro. HIF-2 alpha knockdowns in C2 and 786-O cells is used to evaluate the effect on HDAC 1 expression and activity. Invasion and migration assays are used to investigate the role of HDAC 1 and HDAC 6 expression in ccRCC cells. Comparisons are made between experimental groups using the paired T-test, the two-sample Student's T-test or one-way ANOVA, as appropriate. ccRCC and the TCGA dataset are used to observe the clinical correlation between HDAC 1 and HDAC 6 overexpression and overall and progression free survival.
Results: Our analysis of tumor and matched non-tumor tissues from radical nephrectomies showed overexpression of class I and II HDACs (HDAC6 only in a subset of patients). In vitro, both HDAC1 and HDAC6 over-expression increased cell invasion and motility, respectively, in ccRCC cells. HDAC1 regulated invasiveness by increasing matrix metalloproteinase (MMP) expression. Furthermore, hypoxia stimulation in VHL-reconstituted cell lines increased HIF isoforms and HDAC1 expression. Presence of hypoxia response elements in the HDAC1 promoter along with chromatin immunoprecipitation data suggests that HIF-2 alpha is a transcriptional regulator of HDAC1 gene. Conversely, HDAC6 and estrogen receptor alpha (ER alpha) were co-localized in cytoplasm of ccRCC cells and HDAC6 enhanced cell motility by decreasing acetylated alpha-tubulin expression, and this biological effect was attenuated by either biochemical or pharmacological inhibition. Finally, analysis of human ccRCC specimens revealed positive correlation between HIF isoforms and HDAC. HDAC1 mRNA upregulation was associated with worse overall survival in the TCGA dataset.
Conclusions: Taking together, these results suggest that HDAC1 and HDAC6 may play a role in ccRCC biology and could represent rational therapeutic targets.http://bmccancer.biomedcentral.com/articles/10.1186/s12885-016-2604-
Food Phone Application
This project is about implementing a food menu application for users to search and upload food information by using a mobile phone. People sometimes may just know what food they wish to eat instead of the restaurants\u27 name. Without knowing any restaurants\u27 names, our food application\u27s search only requires the name of the dish (e.g., hamburger, spaghetti, etc) in order to get the list of restaurants that serve these items and their corresponding information (e.g., location, hours, phone number, item\u27s price, etc.). An advantage of using my food application is the system not only includes Google Map, but any information other users have inputted. When a user wants to input a food item, one can either upload the item\u27s picture or a template picture to the server and input the rating and comments about the specific food item. With the rating option, my project calculates a cumulative rating result based around the original and other user\u27s input. There is also the option of having the users input a zip code to better identify where to find the food. Based on the phone\u27s capability, the system also needs to figure out the physical phone location. This requires the phone to receive the GPS signal. As a result, users can search/upload the local restaurants\u27 food without inputting the current location
Effect of the shelterbelt along the Tarim Desert Highway on air temperature and humidity
The temperature and humidity of the shelterbelt micro-climate on both horizontal and vertical scales in the extremely drought area were measured with multiple HOBO temperature and humidity automatic observation equipments in the hinterland of the Taklimakan Desert. The results show that the shelterbelt ecosystem of the desert highway plays typical micro-climate adjustment rolesin stabilizing surface air temperature and increasing air humidity, and so on. Solar radiation significantly affects both temperature and humidity of surface layers, and it has a positive correlation with the temperature but a negative correlation with the air humidity. When it is cloudy, the weather has a great impact on keeping temperature and humidity in the shelterbelt. The shelterbelt also significantly influences the environment, and the micro-climate in the belt has an obvious characteristic of cooling and humidification: compared with the original sand area, the temperature in the shelterbelt is always lower and the humidity is always higher. Moreover, the temperature range at the shelterbelt edge is greater than that in the sand area, but the humidity is always higher. Our conclusion is that the vertical-effect range of temperature of the shelterbelts is 4-10 m, and the humidity range is 6 to 8 m; the horizontal-effect range of temperature is 16 m and the humidity range is about 24 m
Effects of natural covers on soil evaporation of the shelterbelt along the Tarim Desert Highway
The control of soil evaporation is one of important approaches to save water. The artificially simulated evaporation experiments have been conducted in the hinterland of the Taklimakan Desert to reveal the effects of the natural covers on the soil evaporation of the Tarim Desert Highway shelterbelt as well as provide some insights in the efficient utilization of water resources and optimization of irrigation systems. The results showed that (1) All the covers, including the sand deposit, the salt crust, the litter, the sand-litter mixed layer and so on, can significantly inhibit the soil water evaporation. Specifically, the daily evaporation, the total evaporation, and the evaporation rate in covered sands were much smaller than that of sands without cover. The cover inhibition effects increased with the cover thickness. Particularly, the soil evaporation of the covered sands was less affected by external and internal factors than that of the bare sands. Moreover, the variation of daily evaporation of covered sands was smaller than that of bare sands. The cumulative evaporation varied linearly with time in the covered sands whereas it varied logarithmically in the bare sands. In addition, the soil evaporation in the bare sands showed significantly different characteristics in the early and late stages of the evaporation. (2) All the covers exhibited the significant inhibiting effect on the soil evaporation, and the inhibition efficiency increased logarithmically with the cover thickness. However, as the cover thickness was above a certain value, the increase in the inhibition efficiency was slow. Particularly, at a cover thickness of 2 cm, there was no obvious difference in the inhibition efficiency among all kinds of covers. The maximum inhibition efficiency as calculated from the daily evaporation on the first day of irrigation was: sand-litter mixed layer (79.92%) > litter layer (78.96%) > salt crust (75.58%) > sand bed (74.11%), whereas the average inhibiting efficiency as calculated from the cumulative soil evaporation at the end of an irrigation cycle (the fourth day) was: salt crust (67.78%) > sand-litter mixed layer (66.72%) > sand deposit (63.28%) > litter layer (61.74%)
Evaluation of soil fertility of the shelter-forest land along the Tarim Desert Highway
To study the changes of soil fertility of the shelter-forest land along the Tarim Desert Highway, soils from the forest land were collected at the layers of 0-10 cm, 10-20 cm, 20-30 cm. Different soil fertility parameters were measured, and quantitative evaluation of soil fertility was performed by the soil integrated fertility index (IFI). The main results show that the construction of the shelter forest along the Tarim Desert Highway improved the soil physical structure, increased soil porosity and enhanced water-holding capacity. With the increase of plantation time of the shelter forest, soil microbial biomass C, N, P and the activities of six types of enzyme were enhanced, which promoted the accumulation and transformation of soil nutrients of the forest land. Consequently, the soil nutrients in 12-year-old forest land were much higher than in the newer ones and drifting sand. However, soil salt content of the older forest land was higher owing to the drip-irrigation with salt water. Through the comprehensive evaluation, we found that soil fertility index in the forest land was enhanced with the forest age, and it had close correlations with the growth indices of the forest trees. In summary, construction of the shelter-forest along the Tarim Desert Highway accelerated the improvement of aeolian soil in the forest land, and the soil fertility improved year by year. We conclude that the forest trees grow normally under the stress of the present drip-irrigation with salt water
Topographical changes of ground surface affected by the shelterbelt along the Tarim Desert Highway
To study the effects of sand protection project on modern aeolian landform, the types, distribution, and intensity of topographical changes of the ground surface affected by the shelterbelt along the Tarim Desert Highway were determined by measuring the deflation and deposition of sand surface in the Tazhong area located in the hinterland of the Taklimakan Desert. The results showed that (1) the newly-formed landform in sand protection systems is dominated by aeolian deposition including the small-scale Nabkha Dunes, the medium-scale sheet-like sand deposition and the large-scale ridge-like sand deposition. To some degree, aeolian deflation landform can also be formed in the open space in the shelterbelt. Furthermore, it is difficult for aeolian deflation landform to develop in a large scale in the interdunes. However, aeolian deflation landform can be developed in a large-scale on the windward slope of secondary dunes in longitudinal complex sand ridges; (2) on the windward side of the sand protection systems, both the morphology and strike of dwarf mobile dunes in the interdunes are changed by the sand-obstructing forest belts and the ridge-like sand deposition around it. The windward slope of the ridge-like deposition around the sand-obstructing forest belt forms a stable ground surface. After being damaged by forward-moving dunes in a short period, the ground surface is recovered gradually; (3) on the leeward side of the sand protection systems, aeolian deflations are formed widely. Particularly, the deflation depression is formed in the interdunes. In addition, the dunes in the region with highly topographic relief are cut flat by aeolian deflations; thereafter its relief of topography is reduced. The above analysis indicates that shelterbelts have obvious effects on the windward wind-sand flux in terms of dissipating energy and intercepting sand. With the recovery of wind velocity on the leeward side of the sand protection systems, the wind-sand flux gradually tends to be unsaturated; therefore the sand surface deflation is formed
Classification and regionalization of the forming environment of windblown sand disasters along the Tarim Desert Highway
Through the systematic field survey and observations, the factor quantification as well as setting the criteria, the sand disaster-forming environment along the Tarim Desert Highway can be divided into four grades by the classification and regionalization based on fuzzy mathematics. The length of the regions with significant sand disaster accounted for 37.1% of the total highway length. Particularly, the area along the Tarim Desert Highway, based on the sand disaster-forming environment classification as well as the difference in the five basic landform units along the highway, combined with the difference of wind regime, can be divided into five regions, in which the length of the regions suffering severe sand damage occupied 64.3% of the total highway length. In addition, the index of disaster formation grade along the highway decreased from north to south, showing a repeated spatial pattern in small length scales
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