An animal model of SARS produced by infection of Macaca mulatta with SARS coronavirus.

A new SARS animal model was established by inoculating SARS coronavirus (SARS-CoV) into rhesus macaques (Macaca mulatta) through the nasal cavity. Pathological pulmonary changes were successively detected on days 5-60 after virus inoculation. All eight animals showed a transient fever 2-3 days after inoculation. Immunological, molecular biological, and pathological studies support the establishment of this SARS animal model. Firstly, SARS-CoV-specific IgGs were detected in the sera of macaques from 11 to 60 days after inoculation. Secondly, SARS-CoV RNA could be detected in pharyngeal swab samples using nested RT-PCR in all infected animals from 5 days after virus inoculation. Finally, histopathological changes of interstitial pneumonia were found in the lungs during the 60 days after viral inoculation: these changes were less marked at later time points, indicating that an active healing process together with resolution of an acute inflammatory response was taking place in these animals. This animal model should provide insight into the mechanisms of SARS-CoV-related pulmonary disease and greatly facilitate the development of vaccines and therapeutics against SARS

The Cooperative Effect of In 2

Compared with In/HZSM-5 catalyst, In/HZSM-5/In2O3 catalyst that contained two different kinds of In induced by the impregnation and the physical mixing method, respectively, has shown remarkable activity for methane selectively catalytic reduction (CH4-SCR) of NOx. The addition of In2O3 to In/HZSM-5 could improve the NO conversion. When a little In2O3 was added to the In/HZSM-5, the active sites of InO+ which can adsorb NO2 were increased. Moreover, at the internal surface of HZSM-5, highly dispersed In2O3 species could promote oxidation of NO to NO2. The adsorption of NO2 is the key step for the whole reaction, which benefits the activation of methane and the reduction of NOx by methane. Thus the activity of In/HZSM-5/In2O3 for CH4-SCR of NOx was higher than that of In/HZSM-5

Integrated glycomic analysis of ovarian cancer side population cells

Additional file 2. The category of representative lectins for glycan profiling

Form factors of P→TP\to T transition within the light-front quark models

In this paper, we calculate the vector, axial-vector and tensor form factors of $P\to T$ transition within the standard light-front~(SLF) and covariant light-front~(CLF) quark models~(QMs). The self-consistency and Lorentz covariance of CLF QM with two types of correspondence schemes are investigated. The zero-mode effects and the spurious $\omega$-dependent contributions to the form factors of $P\to T$ transition are analyzed. Employing a self-consistent CLF QM, we present our numerical predictions for the vector, axial-vector and tensor form factors of $c\to (q,s)$~($q=u,d$) induced $D \to (a_2,K^*_2)$, $D_s \to (K^*_2,f'_{2})$, $\eta_c(1S) \to (D^*_2,D^*_{s2})$, $B_c \to (B^*_2,B^*_{s2})$ transitions and $b\to (q,s,c)$ induced $B \to (a_2,K^*_2,D^*_2)$, $B_s \to (K^*_2,f'_2,D^*_{s2})$, $B_c \to (D^*_2,D^*_{s2},\chi_{c2}(1P))$, $\eta_b(1S) \to (B^*_2,B^*_{s2})$ transitions. Finally, in order to test the obtained form factors, the semileptonic $B\to \bar{D}_2^*(2460)\ell^+\nu_\ell$~($\ell=e,\mu$) and $\bar{D}_2^*(2460)\tau^+\nu_{\tau}$ decays are studied. It is expected that our results for the form factors of $P\to T$ transition can be applied further to the relevant phenomenological studies of meson decays.Comment: 41 pages, 7figures. arXiv admin note: text overlap with arXiv:1908.0467

Comparison of the Effects of Fluidized-Bed and Fixed-Bed Reactors in Microwave-Assisted Catalytic Decomposition of TCE by Hydrogen

Trichloroethylene (TCE) decomposition by hydrogen with microwave heating under different reaction systems was investigated. The activities of a series of catalysts for microwave-assisted TCE hydrodechlorination were tested through the fixed-bed and the fluidized-bed reactor systems. This study found that the different reaction system is suitable for different catalyst type. And there is an interactive relationship between the catalyst type and the reaction bed type