Significantly reduced radiation dose to operators during percutaneous vertebroplasty using a new cement delivery device

BACKGROUND: Percutaneous vertebroplasy (PVP) might lead to significant radiation exposure to patients, operators, and operating room personnel. Therefore, radiaton exposure is a concern. The aim of this study was to present a remote control cement delivery device and study whether it can reduce dose exposue to operators. METHODS: After meticulous preoperative preparation, a series of 40 osteoporosis patients were treated with unilateral approach PVP using the new cement delivery divice. We compared levels of fluoroscopic exposure to operator standing on different places during operation. group A: operator stood about 4 meters away from X-ray tube behind the lead sheet. group B: operator stood adjacent to patient as using conventional manual cement delivery device. RESULTS: During whole operation process, radiation dose to the operator (group A) was 0.10 ± 0.03 (0.07-0.15) μSv, group B was 12.09 ± 4.67 (10–20) μSv. a difference that was found to be statistically significant (P < 0.001) between group A and group B. CONCLUSION: New cement delivery device plus meticulous preoperative preparation can significantly decrease radiation dose to operators

Paracrine mechanisms of Mesenchymal Stem cell-based therapy: Current status and perspectives.

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Activation of NRG1-ERBB4 signaling potentiates mesenchymal stem cell-mediated myocardial repairs following myocardial infarction

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Feature technology and its applications in computer integrated manufacturing

A Thesis submitted for the degree of Doctor of Philosophy of University of LutonComputer aided design and manufacturing (CAD/CAM) has been a focal research area for the manufacturing industry. Genuine CAD/CAM integration is necessary to make products of higher quality with lower cost and shorter lead times. Although CAD and CAM have been extensively used in industry, effective CAD/CAM integration has not been implemented. The major obstacles of CAD/CAM integration are the representation of design and process knowledge and the adaptive ability of computer aided process planning (CAPP). This research is aimed to develop a feature-based CAD/CAM integration methodology. Artificial intelligent techniques such as neural networks, heuristic algorithms, genetic algorithms and fuzzy logics are used to tackle problems. The activities considered include: 1) Component design based on a number of standard feature classes with validity check. A feature classification for machining application is defined adopting ISO 10303-STEP AP224 from a multi-viewpoint of design and manufacture. 2) Search of interacting features and identification of features relationships. A heuristic algorithm has been proposed in order to resolve interacting features. The algorithm analyses the interacting entity between each feature pair, making the process simpler and more efficient. 3) Recognition of new features formed by interacting features. A novel neural network-based technique for feature recognition has been designed, which solves the problems of ambiguity and overlaps. 4) Production of a feature based model for the component. 5) Generation of a suitable process plan covering selection of machining operations, grouping of machining operations and process sequencing. A hybrid feature-based CAPP has been developed using neural network, genetic algorithm and fuzzy evaluating techniques

An inventory of invasive alien species in China

Invasive alien species (IAS) are a major global challenge requiring urgent action, and the Strategic Plan for Biodiversity (2011–2020) of the Convention on Biological Diversity (CBD) includes a target on the issue. Meeting the target requires an understanding of invasion patterns. However, national or regional analyses of invasions are limited to developed countries. We identified 488 IAS in China’s terrestrial habitats, inland waters and marine ecosystems based on available literature and field work, including 171 animals, 265 plants, 26 fungi, 3 protists, 11 procaryots, and 12 viruses. Terrestrial plants account for 51.6% of the total number of IAS, and terrestrial invertebrates (104 species) for 21.3%. Of the total numbers, 67.9% of plant IAS and 34.8% of animal IAS were introduced intentionally. All other taxa were introduced unintentionally despite very few animal and plant species that invaded naturally. In terms of habitats, 64.3% of IAS occur on farmlands, 13.9% in forests, 8.4% in marine ecosystems, 7.3% in inland waters, and 6.1% in residential areas. Half of all IAS (51.1%) originate from North and South America, 18.3% from Europe, 17.3% from Asia not including China, 7.2% from Africa, 1.8% from Oceania, and the origin of the remaining 4.3% IAS is unknown. The distribution of IAS can be divided into three zones. Most IAS are distributed in coastal provinces and the Yunnan province; provinces in Middle China have fewer IAS, and most provinces in West China have the least number of IAS. Sites where IAS were first detected are mainly distributed in the coastal region, the Yunnan Province and the Xinjiang Uyghur Autonomous Region. The number of newly emerged IAS has been increasing since 1850. The cumulative number of firstly detected IAS grew exponentially

Design of non-fragile state estimators for discrete time-delayed neural networks with parameter uncertainties

This paper is concerned with the problem of designing a non-fragile state estimator for a class of uncertain discrete-time neural networks with time-delays. The norm-bounded parameter uncertainties enter into all the system matrices, and the network output is of a general type that contains both linear and nonlinear parts. The additive variation of the estimator gain is taken into account that reflects the possible implementation error of the neuron state estimator. The aim of the addressed problem is to design a state estimator such that the estimation performance is non-fragile against the gain variations and also robust against the parameter uncertainties. Sufficient conditions are presented to guarantee the existence of the desired non-fragile state estimators by using the Lyapunov stability theory and the explicit expression of the desired estimators is given in terms of the solution to a linear matrix inequality. Finally, a numerical example is given to demonstrate the effectiveness of the proposed design approach