17,453 research outputs found
Quantum computation in decoherence-free subspace with superconducting devices
We propose a scheme to implement quantum computation in decoherence-free
subspace with superconducting devices inside a cavity by unconventional
geometric manipulation. Universal single-qubit gates in encoded qubit can be
achieved with cavity assisted interaction. A measurement-based two-qubit
Controlled-Not gate is produced with parity measurements assisted by an
auxiliary superconducting device and followed by prescribed single-qubit gates.
The measurement of currents on two parallel devices can realize a projective
measurement, which is equivalent to the parity measurement on the involved
devices.Comment: v2: thoroughly rewritten version with title and motivation changed;
v3: published version with detail dirivation
Estimation and model selection in generalized additive partial linear models for correlated data with diverging number of covariates
We propose generalized additive partial linear models for complex data which
allow one to capture nonlinear patterns of some covariates, in the presence of
linear components. The proposed method improves estimation efficiency and
increases statistical power for correlated data through incorporating the
correlation information. A unique feature of the proposed method is its
capability of handling model selection in cases where it is difficult to
specify the likelihood function. We derive the quadratic inference
function-based estimators for the linear coefficients and the nonparametric
functions when the dimension of covariates diverges, and establish asymptotic
normality for the linear coefficient estimators and the rates of convergence
for the nonparametric functions estimators for both finite and high-dimensional
cases. The proposed method and theoretical development are quite challenging
since the numbers of linear covariates and nonlinear components both increase
as the sample size increases. We also propose a doubly penalized procedure for
variable selection which can simultaneously identify nonzero linear and
nonparametric components, and which has an asymptotic oracle property.
Extensive Monte Carlo studies have been conducted and show that the proposed
procedure works effectively even with moderate sample sizes. A pharmacokinetics
study on renal cancer data is illustrated using the proposed method.Comment: Published in at http://dx.doi.org/10.1214/13-AOS1194 the Annals of
Statistics (http://www.imstat.org/aos/) by the Institute of Mathematical
Statistics (http://www.imstat.org
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Multistaged discharge constructing heterostructure with enhanced solid-solution behavior for long-life lithium-oxygen batteries.
Inferior charge transport in insulating and bulk discharge products is one of the main factors resulting in poor cycling stability of lithium-oxygen batteries with high overpotential and large capacity decay. Here we report a two-step oxygen reduction approach by pre-depositing a potassium carbonate layer on the cathode surface in a potassium-oxygen battery to direct the growth of defective film-like discharge products in the successive cycling of lithium-oxygen batteries. The formation of defective film with improved charge transport and large contact area with a catalyst plays a critical role in the facile decomposition of discharge products and the sustained stability of the battery. Multistaged discharge constructing lithium peroxide-based heterostructure with band discontinuities and a relatively low lithium diffusion barrier may be responsible for the growth of defective film-like discharge products. This strategy offers a promising route for future development of cathode catalysts that can be used to extend the cycling life of lithium-oxygen batteries
Scheme for remote implementation of partially unknown quantum operation of two qubits in cavity QED
By constructing the recovery operations of the protocol of remote
implementation of partially unknown quantum operation of two qubits [An Min
Wang: PRA, \textbf{74}, 032317(2006)], we present a scheme to implement it in
cavity QED. Long-lived Rydberg atoms are used as qubits, and the interaction
between the atoms and the field of cavity is a nonresonant one. Finally, we
analyze the experimental feasibility of this scheme.Comment: 7 pages, 2 figure
On the Universal Approximation Property and Equivalence of Stochastic Computing-based Neural Networks and Binary Neural Networks
Large-scale deep neural networks are both memory intensive and
computation-intensive, thereby posing stringent requirements on the computing
platforms. Hardware accelerations of deep neural networks have been extensively
investigated in both industry and academia. Specific forms of binary neural
networks (BNNs) and stochastic computing based neural networks (SCNNs) are
particularly appealing to hardware implementations since they can be
implemented almost entirely with binary operations. Despite the obvious
advantages in hardware implementation, these approximate computing techniques
are questioned by researchers in terms of accuracy and universal applicability.
Also it is important to understand the relative pros and cons of SCNNs and BNNs
in theory and in actual hardware implementations. In order to address these
concerns, in this paper we prove that the "ideal" SCNNs and BNNs satisfy the
universal approximation property with probability 1 (due to the stochastic
behavior). The proof is conducted by first proving the property for SCNNs from
the strong law of large numbers, and then using SCNNs as a "bridge" to prove
for BNNs. Based on the universal approximation property, we further prove that
SCNNs and BNNs exhibit the same energy complexity. In other words, they have
the same asymptotic energy consumption with the growing of network size. We
also provide a detailed analysis of the pros and cons of SCNNs and BNNs for
hardware implementations and conclude that SCNNs are more suitable for
hardware.Comment: 9 pages, 3 figure
Is a Molecular State?
Whether molecular states indeed exist in nature has been disputed for a long
time. Several new resonances have been observed in the recent experiments and
they seem to be of exotic structures and some of them have been proposed to be
molecular states. The very recent observation of
MeV] and MeV] encourages the interpretation of
multi-quark states. In the Beter-Salpeter (BS) approach, we study the
possibility if two heavy mesons can form a molecular state by exchanging light
mesons. Our results indicate that two heavy mesons can form an isospin singlet
(I=0) bound state but cannot form an isospin triplet (I=1) when the
contribution of exchange is reasonably small, i.e. as the coupling of
with mesons takes the value given in previous
literatures. Thus we conclude that the newly observed should not
be a molecular state, but a tetraquark state instead, at most, the fraction of
the molecular state in the physical resonance is tiny.Comment: 15 pages, 2 figures, an important reference added; Accepted by JHE
Robust interface between flying and topological qubits
Hybrid architectures, consisting of conventional and topological qubits, have
recently attracted much attention due to their capability in consolidating the
robustness of topological qubits and the universality of conventional qubits.
However, these two kinds of qubits are normally constructed in significantly
different energy scales, and thus this energy mismatch is a major obstacle for
their coupling that supports the exchange of quantum information between them.
Here, we propose a microwave photonic quantum bus for a direct strong coupling
between the topological and conventional qubits, in which the energy mismatch
is compensated by the external driving field via the fractional ac Josephson
effect. In the framework of tight-binding simulation and perturbation theory,
we show that the energy splitting of the topological qubits in a finite length
nanowire is still robust against local perturbations, which is ensured not only
by topology, but also by the particle-hole symmetry. Therefore, the present
scheme realizes a robust interface between the flying and topological qubits.
Finally, we demonstrate that this quantum bus can also be used to generate
multipartitie entangled states with the topological qubits.Comment: Accepted for publication in Scientific Report
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Hypericin enhances β-lactam antibiotics activity by inhibiting sarA expression in methicillin-resistant Staphylococcus aureus.
Bacteremia is a life-threating syndrome often caused by methicillin-resistant Staphylococcus aureus (MRSA). Thus, there is an urgent need to develop novel approaches to successfully treat this infection. Staphylococcal accessory regulator A (SarA), a global virulence regulator, plays a critical role in pathogenesis and β-lactam antibiotic resistance in Staphylococcus aureus. Hypericin is believed to act as an antibiotic, antidepressant, antiviral and non-specific kinase inhibitor. In the current study, we investigated the impact of hypericin on β-lactam antibiotics susceptibility and mechanism(s) of its activity. We demonstrated that hypericin significantly decreased the minimum inhibitory concentrations of β-lactam antibiotics (e.g., oxacillin, cefazolin and nafcillin), biofilm formation and fibronectin binding in MRSA strain JE2. In addition, hypericin significantly reduced sarA expression, and subsequently decreased mecA, and virulence-related regulators (e.g., agr RNAⅢ) and genes (e.g., fnbA and hla) expression in the studied MRSA strain. Importantly, the in vitro synergistic effect of hypericin with β-lactam antibiotic (e.g., oxacillin) translated into in vivo therapeutic outcome in a murine MRSA bacteremia model. These findings suggest that hypericin plays an important role in abrogation of β-lactam resistance against MRSA through sarA inhibition, and may allow us to repurpose the use of β-lactam antibiotics, which are normally ineffective in the treatment of MRSA infections (e.g., oxacillin)
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