Long Duration Exposure Facility: A general overview

The Long Duration Exposure Facility (LDEF) is a large, low-cost, reusable, unmanned, free-flying spacecraft which accommodates technology, science, and applications experiments for long-term exposure to the space environment. The LDEF was designed and built by the NASA Langley Research Center (LaRC) for NASA's Office of Aeronautics and Space Technology. Specifically, the LDEF was designed to transport experiments into space via the Space Shuttle, to free fly in Earth orbit for an extended period, and be retrieved on a later Space Shuttle flight allowing experiments to be returned to Earth for postflight analysis in the laboratory. The LDEF with a full complement of experiments was placed in Earth orbit in April 1984 by Challenger and retrieved from orbit in January 1990 by Columbia. A general overview of the LDEF, its mission, systems, experiments, and operations is presented. Excerpts from various NASA documents are extensively used

A bi-criteria evolutionary algorithm for a constrained multi-depot vehicle routing problem

Most research about the vehicle routing problem (VRP) does not collectively address many of the constraints that real-world transportation companies have regarding route assignments. Consequently, our primary objective is to explore solutions for real-world VRPs with a heterogeneous fleet of vehicles, multi-depot subcontractors (drivers), and pickup/delivery time window and location constraints. We use a nested bi-criteria genetic algorithm (GA) to minimize the total time to complete all jobs with the fewest number of route drivers. Our model will explore the issue of weighting the objectives (total time vs. number of drivers) and provide Pareto front solutions that can be used to make decisions on a case-by-case basis. Three different real-world data sets were used to compare the results of our GA vs. transportation field experts’ job assignments. For the three data sets, all 21 Pareto efficient solutions yielded improved overall job completion times. In 57 % (12/21) of the cases, the Pareto efficient solutions also utilized fewer drivers than the field experts’ job allocation strategies

Linguistics

Contains reports on one research project.National Science Foundation (Grant GP-2495)National Institutes of Health (Grant MH-04737-05)National Aeronautics and Space Administration (Grant NsG-496)U. S. Air Force (Electronic Systems Division) under Contract AF 19(628)- 248

The load shedding advisor: An example of a crisis-response expert system

A Prolog-based prototype expert system is described that was implemented by the Network Operations Branch of the NASA Goddard Space Flight Center. The purpose of the prototype was to test whether a small, inexpensive computer system could be used to host a load shedding advisor, a system which would monitor major physical environment parameters in a computer facility, then recommend appropriate operator reponses whenever a serious condition was detected. The resulting prototype performed significantly to efficiency gains achieved by replacing a purely rule-based design methodology with a hybrid approach that combined procedural, entity-relationship, and rule-based methods

Linguistics

Contains reports on three research projects.National Science Foundation (Grant GP-2495)National Institutes of Health (Grant MH-04737-04)U. S. Air Force. Electronics Systems Division (Contract AFl9(628)-2487)National Aeronautics and Space Administration (Grant NsG-496

The Fetal Allograft Revisited: Does the Study of an Ancient Invertebrate Species Shed Light on the Role of Natural Killer Cells at the Maternal-Fetal Interface?

Human pregnancy poses a fundamental immunological problem because the placenta and fetus are genetically different from the host mother. Classical transplantation theory has not provided a plausible solution to this problem. Study of naturally occurring allogeneic chimeras in the colonial marine invertebrate, Botryllus schlosseri, has yielded fresh insight into the primitive development of allorecognition, especially regarding the role of natural killer (NK) cells. Uterine NK cells have a unique phenotype that appears to parallel aspects of the NK-like cells in the allorecognition system of B. schlosseri. Most notably, both cell types recognize and reject "missing self" and both are involved in the generation of a common vascular system between two individuals. Chimeric combination in B. schlosseri results in vascular fusion between two individual colonies; uterine NK cells appear essential to the establishment of adequate maternal-fetal circulation. Since human uterine NK cells appear to de-emphasize primary immunological function, it is proposed that they may share the same evolutionary roots as the B. schlosseri allorecognition system rather than a primary origin in immunity

Linguistics

Contains reports on six research projects.National Institutes of Health (Grant MH-04737-03)National Science Foundation (Grant G-16526)National Aeronautics and Space Administration (Grant NsG-496)United States Air Force, Electronic Systems Division (Contract AF19(628)-2487

Inverse Raman spectroscopy of bilirubin and its ditauride

The inverse Raman spectrum of bilirubin and bilirubin ditauride were measured under pre‐resonant conditions. Spectra in chloroform and dimethyl sulfoxide were assigned by comparison with model compounds and on the basis of the known effects of the solvents on the internal hydrogen bonding in bilirubin. The band assignments were used to interpret the spectra of bilirubin ditauride in aqueous solution. Evidence is presented for strong hydrogen bonding to the pyrrole NH bonds and to the lactam rings. It is proposed that hydrogen bonding to water is facilitated by photoactivation and, in turn, stabilizes photohiliruhin.Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/91227/1/1250150416_ftp.pd

Linguistics

Contains research objectives and reports on three research projects.National Science Foundation (Grant GP-2495)National Institutes of Health (Grant MH-04737-04)National Aeronautics and Space Administration (Grant NsG-496)U. S. Air Force (Electronic Systems Division) under Contract AF19(628)-248