1,031 research outputs found
Fermionic partner of Quintessence field as candidate for dark matter
Quintessence is a possible candidate for dark energy. In this paper we study
the phenomenologies of the fermionic partner of Quintessence, the Quintessino.
Our results show that, for suitable choices of the model parameters, the
Quintessino is a good candidate for cold or warm dark matter. In our scenario,
dark energy and dark matter of the Universe are connected in one chiral
superfield.Comment: 4 pages, 3 figures, version to appear in PR
Particle physics models of inflation
Inflation models are compared with observation on the assumption that the
curvature perturbation is generated from the vacuum fluctuation of the inflaton
field. The focus is on single-field models with canonical kinetic terms,
classified as small- medium- and large-field according to the variation of the
inflaton field while cosmological scales leave the horizon. Small-field models
are constructed according to the usual paradigm for beyond Standard Model
physicsComment: Based on a talk given at the 22nd IAP Colloquium, ``Inflation +25'',
Paris, June 2006 Curve omitted from final Figur
Исследование температурного поля пневматического молотка
Представлены результаты экспериментального исследования изменения температуры поверхности рубильного пневматического молотка М-6 по времени при рубке в различных режимах стальной полосы и плиты, чугунной плиты
Leukocyte telomere length in paediatric critical illness
__Background:__ Children who have suffered from critical illnesses that required treatment in a paediatric intensive care unit (PICU) have long-term physical and neurodevelopmental impairments. The mechanisms underlying this legacy remain largely unknown. In patients suffering from chronic diseases hallmarked by inflammation and oxidative stress, poor long-term outcome has been associated with shorter telomeres. Shortened telomeres have also been reported to result from excessive food consumption and/or unhealthy nutrition. We investigated whether critically ill children admitted to the PICU have shorter-than-normal telomeres, and whether early parenteral nutrition (PN) independently affects telomere length when adjusting for known determinants of telomere length.
__Methods:__ Telomere length was quantified in leukocyte DNA from 342 healthy children and from 1148 patients who had been enrolled in the multicenter, randomised controlled trial (RCT), PEPaNIC. These patients were randomly allocated to initiation of PN within 24 h (early PN) or to withholding PN for one week in PICU (late PN). The impact of early PN versus late PN on the change in telomere length from the first to last PICU-day was investigated with multivariable linear regression analyses.
__Results:__ Leukocyte telomeres were 6% shorter than normal upon PICU admission (median 1.625 (IQR 1.446-1.825) telomere/single-copy-gene ratio (T/S) units vs. 1.727 (1.547-1.915) T/S-units in healthy children (P < 0.0001)). Adjusted for potential baseline determinants and leukocyte composition, early PN was associated with telomere shortening during PICU stay as compared with late PN (estimate early versus late PN -0.021 T/S-units, 95% CI -0.038; 0.004, P = 0.01). Other independent determinants of telomere length identified in this model were age, gender, baseline telomere length and fraction of neutrophils in the sample from which the DNA was extracted. Telomere shortening with early PN was independent of post-randomisation factors affected by early PN, including longer length of PICU stay, larger amounts of insulin and higher risk of infection.
__Conclusions:__ Shorter than normal leukocyte telomeres are present in critically ill children admitted to the PICU. Early initiation of PN further shortened telomeres, an effect that was independent of other determinants. Whether such telomere-shortening predisposes to long-term consequences of paediatric critical illness should be further investigated in a prospective follow-up study
Mean-field description of ground-state properties of drip-line nuclei. (I) Shell-correction method
A shell-correction method is applied to nuclei far from the beta stability
line and its suitability to describe effects of the particle continuum is
discussed. The sensitivity of predicted locations of one- and two-particle drip
lines to details of the macroscopic-microscopic model is analyzed.Comment: 22 REVTeX pages, 13 uuencoded postscript figures available upon
reques
Observational Constraints on the Modified Gravity Model (MOG) Proposed by Moffat: Using the Magellanic System
A simple model for the dynamics of the Magellanic Stream (MS), in the
framework of modified gravity models is investigated. We assume that the galaxy
is made up of baryonic matter out of context of dark matter scenario. The model
we used here is named Modified Gravity (MOG) proposed by Moffat (2005). In
order to examine the compatibility of the overall properties of the MS under
the MOG theory, the observational radial velocity profile of the MS is compared
with the numerical results using the fit method. In order to obtain
the best model parameters, a maximum likelihood analysis is performed. We also
compare the results of this model with the Cold Dark Matter (CDM) halo model
and the other alternative gravity model that proposed by Bekenstein (2004), so
called TeVeS. We show that by selecting the appropriate values for the free
parameters, the MOG theory seems to be plausible to explain the dynamics of the
MS as well as the CDM and the TeVeS models.Comment: 14 pages, 3 Figures, accepted in Int. J. Theor. Phy
A role for XRCC2 gene polymorphisms in breast cancer risk and survival
Background
The XRCC2 gene is a key mediator in the homologous recombination repair of DNA double strand breaks. It is hypothesised that inherited variants in the XRCC2 gene might also affect susceptibility to, and survival from, breast cancer.
Methods
The study genotyped 12 XRCC2 tagging single nucleotide polymorphisms (SNPs) in 1131 breast cancer cases and 1148 controls from the Sheffield Breast Cancer Study (SBCS), and examined their associations with breast cancer risk and survival by estimating ORs and HRs, and their corresponding 95% CIs. Positive findings were further investigated in 860 cases and 869 controls from the Utah Breast Cancer Study (UBCS) and jointly analysed together with available published data for breast cancer risk. The survival findings were further confirmed in studies (8074 cases) from the Breast Cancer Association Consortium (BCAC).
Results
The most significant association with breast cancer risk in the SBCS dataset was the XRCC2 rs3218408 SNP (recessive model p=2.3×10−4, minor allele frequency (MAF)=0.23). This SNP yielded an ORrec of 1.64 (95% CI 1.25 to 2.16) in a two-site analysis of SBCS and UBCS, and a meta-ORrec of 1.33 (95% CI 1.12 to 1.57) when all published data were included. This SNP may mark a rare risk haplotype carried by two in 1000 of the control population. Furthermore, the XRCC2 coding R188H SNP (rs3218536, MAF=0.08) was significantly associated with poor survival, with an increased per-allele HR of 1.58 (95% CI 1.01 to 2.49) in a multivariate analysis. This effect was still evident in a pooled meta-analysis of 8781 breast cancer patients from the BCAC (HR 1.19, 95% CI 1.05 to 1.36; p=0.01).
Conclusions
These findings suggest that XRCC2 SNPs may influence breast cancer risk and survival
Search for direct production of charginos and neutralinos in events with three leptons and missing transverse momentum in √s = 7 TeV pp collisions with the ATLAS detector
A search for the direct production of charginos and neutralinos in final states with three electrons or muons and missing transverse momentum is presented. The analysis is based on 4.7 fb−1 of proton–proton collision data delivered by the Large Hadron Collider and recorded with the ATLAS detector. Observations are consistent with Standard Model expectations in three signal regions that are either depleted or enriched in Z-boson decays. Upper limits at 95% confidence level are set in R-parity conserving phenomenological minimal supersymmetric models and in simplified models, significantly extending previous results
The evolution of galaxy groups and of galaxies therein
Properties of groups of galaxies depend sensitively on the algorithm for
group selection, and even the most recent catalogs of groups built from
redshift-space selection should suffer from projections and infalling galaxies.
The cosmo-dynamical evolution of groups from initial Hubble expansion to
collapse and virialization leads to a fundamental track (FT) in
virial-theorem-M/L vs crossing time. The increased rates of mergers, both
direct and after dynamical friction, in groups relative to clusters, explain
the higher fraction of elliptical galaxies at given local number density in
X-ray selected groups, relative to clusters, even when the hierarchical
evolution of groups is considered. Galaxies falling into groups and clusters
should later travel outwards to typically 2 virial radii, which is somewhat
less than the outermost radius where observed galaxy star formation
efficiencies are enhanced relative to field galaxies of same morphological
type. An ongoing analysis of the internal kinematics of X-ray selected groups
suggests that the radial profiles of line of sight velocity dispersion are
consistent with isotropic NFW distributions for the total mass density, with
higher (lower) concentrations than LambdaCDM predictions in groups of high
(low) mass. The critical mass, at M200 ~ 10^13 M_sun is consistent with
possible breaks in the X-ray luminosity-temperature and Fundamental Plane
relations. The internal kinematics of groups indicate that the M-T relation of
groups should agree with that extrapolated from clusters with no break at the
group scale. The analyses of observed velocity dispersion profiles and of the
FT both suggest that low velocity dispersion groups (compact and loose, X-ray
emitting or undetected) are quite contaminated by chance projections.Comment: Invited review, ESO workshop "Groups of Galaxies in the Nearby
Universe", held in Santiago, Chile, 5-9 December 2005, ed. I. Saviane, V.
Ivanov & J. Borissova, 16 page
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