3,018 research outputs found
INTERNATIONALIZATION OF GERMAN COMPANIES INTO THE CHINESE MARKET - AN EVENT STUDY ON THE CONSEQUENCES ON FINANCIAL PERFORMANCE FROM A RBV PERSPECTIVE
After its economic opening in 1978, China has become more and more attractive for foreign direct investments and has developed into a strong internationalization target for other countries. This study analyzes the internationalization-performance relationship of German companies entering the Chinese market. The analysis is carried out for a sample of 257 announcements of the internationalization of German firms into China between 1978 and 2005. The event study methodology is used to measure the German stock market reaction to this event in order to enable a conclusion on the creation or destruction of share-holder value of German firms internationalizing into China.Internationalization, market entry, China, financial performance
A Bayesian fusion model for space-time reconstruction of finely resolved velocities in turbulent flows from low resolution measurements
The study of turbulent flows calls for measurements with high resolution both
in space and in time. We propose a new approach to reconstruct
High-Temporal-High-Spatial resolution velocity fields by combining two sources
of information that are well-resolved either in space or in time, the
Low-Temporal-High-Spatial (LTHS) and the High-Temporal-Low-Spatial (HTLS)
resolution measurements. In the framework of co-conception between sensing and
data post-processing, this work extensively investigates a Bayesian
reconstruction approach using a simulated database. A Bayesian fusion model is
developed to solve the inverse problem of data reconstruction. The model uses a
Maximum A Posteriori estimate, which yields the most probable field knowing the
measurements. The DNS of a wall-bounded turbulent flow at moderate Reynolds
number is used to validate and assess the performances of the present approach.
Low resolution measurements are subsampled in time and space from the fully
resolved data. Reconstructed velocities are compared to the reference DNS to
estimate the reconstruction errors. The model is compared to other conventional
methods such as Linear Stochastic Estimation and cubic spline interpolation.
Results show the superior accuracy of the proposed method in all
configurations. Further investigations of model performances on various range
of scales demonstrate its robustness. Numerical experiments also permit to
estimate the expected maximum information level corresponding to limitations of
experimental instruments.Comment: 15 pages, 6 figure
Effects of propidium monoazide (PMA) treatment on mycobiome and bacteriome analysis of cystic fibrosis airways during exacerbation
Introduction and Purpose : Propidium monoazide (PMA)-pretreatment has increasingly been applied to remove the bias from dead or damaged cell artefacts, which could impact the microbiota analysis by high-throughput sequencing. Our study aimed to determine whether a PMA-pretreatment coupled with high-throughput sequencing analysis provides a different picture of the airway mycobiome and bacteriome.
Results and Discussion : We compared deep-sequencing data of mycobiota and microbiota of 15 sputum samples from 5 cystic fibrosis (CF) patients with and without prior PMA-treatment of the DNA-extracts. PMA-pretreatment had no significant effect on the entire and abundant bacterial community (genera expressed as operational taxonomic units (OTUs) with a relative abundance greater than or equal to 1%), but caused a significant difference in the intermediate community (less than 1%) when analyzing the alpha biodiversity Simpson index (p = 0.03). Regarding PMA impact on the airway mycobiota evaluated for the first time here; no significant differences in alpha diversity indexes between PMA-treated and untreated samples were observed. Regarding beta diversity analysis, the intermediate communities also differed more dramatically than the total and abundant ones when studying both mycobiome and bacteriome. Our results showed that only the intermediate (or low abundance) population diversity is impacted by PMA-treatment, and therefore that abundant taxa are mostly viable during acute exacerbation in CF. Given such a cumbersome protocol (PMA-pretreatment coupled with high-throughput sequencing), we discuss its potential interest within the follow-up of CF patients. Further studies using PMA-pretreatment are warranted to improve our "omic" knowledge of the CF airways
On Bisimulations for Description Logics
We study bisimulations for useful description logics. The simplest among the
considered logics is (a variant of PDL). The others
extend that logic with inverse roles, nominals, quantified number restrictions,
the universal role, and/or the concept constructor for expressing the local
reflexivity of a role. They also allow role axioms. We give results about
invariance of concepts, TBoxes and ABoxes, preservation of RBoxes and knowledge
bases, and the Hennessy-Milner property w.r.t. bisimulations in the considered
description logics. Using the invariance results we compare the expressiveness
of the considered description logics w.r.t. concepts, TBoxes and ABoxes. Our
results about separating the expressiveness of description logics are naturally
extended to the case when instead of we have any sublogic
of that extends . We also provide results
on the largest auto-bisimulations and quotient interpretations w.r.t. such
equivalence relations. Such results are useful for minimizing interpretations
and concept learning in description logics. To deal with minimizing
interpretations for the case when the considered logic allows quantified number
restrictions and/or the constructor for the local reflexivity of a role, we
introduce a new notion called QS-interpretation, which is needed for obtaining
expected results. By adapting Hopcroft's automaton minimization algorithm and
the Paige-Tarjan algorithm, we give efficient algorithms for computing the
partition corresponding to the largest auto-bisimulation of a finite
interpretation.Comment: 42 page
Policy Response, Social Media and Science Journalism for the Sustainability of the Public Health System Amid the COVID-19 Outbreak: The Vietnam Lessons
Vietnam, with a geographical proximity and a high volume of trade with China, was the first country to record an outbreak of the new Coronavirus disease (COVID-19), caused by the Severe Acute Respiratory Syndrome Coronavirus 2 or SARS-CoV-2. While the country was expected to have a high risk of transmission, as of April 4, 2020—in comparison to attempts to contain the disease around the world—responses from Vietnam are being seen as prompt and effective in protecting the interests of its citizens, with 239 confirmed cases and no fatalities. This study analyzes the situation in terms of Vietnam’s policy response, social media and science journalism. A self-made web crawl engine was used to scan and collect official media news related to COVID-19 between the beginning of January and April 4, yielding a comprehensive dataset of 14,952 news items. The findings shed light on how Vietnam—despite being under-resourced—has demonstrated political readiness to combat the emerging pandemic since the earliest days. Timely communication on any developments of the outbreak from the government and the media, combined with up-to-date research on the new virus by the Vietnamese science community, have altogether provided reliable sources of information. By emphasizing the need for immediate and genuine cooperation between government, civil society and private individuals, the case study offers valuable lessons for other nations concerning not only the concurrent fight against the COVID-19 pandemic but also the overall responses to a public health crisis
Evaluating the Impact of a HIV Low-Risk Express Care Task-Shifting Program: A Case Study of the Targeted Learning Roadmap
In conducting studies on an exposure of interest, a systematic roadmap should be applied for translating causal questions into statistical analyses and interpreting the results. In this paper we describe an application of one such roadmap applied to estimating the joint effect of both time to availability of a nurse-based triage system (low risk express care (LREC)) and individual enrollment in the program among HIV patients in East Africa. Our study population is comprised of 16;513 subjects found eligible for this task-shifting program within 15 clinics in Kenya between 2006 and 2009, with each clinic starting the LREC program between 2007 and 2008. After discretizing followup into 90-day time intervals, we targeted the population mean counterfactual outcome (i.e. counterfactual probability of either dying or being lost to follow up) at up to 450 days after initial LREC eligibility under three fixed treatment interventions. These were (i) under no program availability during the entire follow-up, (ii) under immediate program availability at initial eligibility, but non-enrollment during the entire follow-up, and (iii) under immediate program availability and enrollment at initial eligibility. We further estimated the controlled direct effect of immediate program availability compared to no program availability, under a hypothetical intervention to prevent individualenrollment in the program. Targeted minimum loss-based estimation was used to estimate the mean outcome, while Super Learning was implemented to estimate the required nuisance parameters. Analyses were conducted with the ltmle R package; analysis code is available at an online repository as an R package. Results showed that at 450 days, the probability of in-care survival for subjects with immediate availability and enrollment was 0:93 (95% CI: 0.91, 0.95) and 0:87 (95% CI: 0.86, 0.87) for subjects with immediate availability never enrolling. For subjects without LREC availability, it was 0:91 (95% CI: 0.90, 0.92). Immediate program availability without individualenrollment, compared to no program availability, was estimated to slightly albeit significantly decrease survival by 4% (95% CI 0.03,0.06, p\u3c 0:01). Immediately availability and enrollment resulted in a 7% higher in-care survival compared to immediate availability with non-enrollment after 450 days (95% CI -0.08,-0.05, p\u3c 0:01). The results are consistent with a fairly small impact of both availability and enrollment in the LREC program on in-care survival
Reaching a Consensus on Random Networks: The Power of Few
A community of n individuals splits into two camps, Red and Blue. The individuals are connected by a social network, which influences their colors. Everyday, each person changes his/her color according to the majority of his/her neighbors. Red (Blue) wins if everyone in the community becomes Red (Blue) at some point.
We study this process when the underlying network is the random Erdos-Renyi graph G(n, p). With a balanced initial state (n/2 persons in each camp), it is clear that each color wins with the same probability.
Our study reveals that for any constants p and ?, there is a constant c such that if one camp has n/2 + c individuals at the initial state, then it wins with probability at least 1 - ?. The surprising fact here is that c does not depend on n, the population of the community. When p = 1/2 and ? = .1, one can set c = 6, meaning one camp has n/2 + 6 members initially. In other words, it takes only 6 extra people to win an election with overwhelming odds. We also generalize the result to p = p_n = o(1) in a separate paper
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