5,418 research outputs found

    Near-Infrared Super Resolution Imaging with Metallic Nanoshell Particle Chain Array

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    We propose a near-infrared super resolution imaging system without a lens or a mirror but with an array of metallic nanoshell particle chain. The imaging array can plasmonically transfer the near-field components of dipole sources in the incoherent and coherent manners and the super resolution images can be reconstructed in the output plane. By tunning the parameters of the metallic nanoshell particle, the plasmon resonance band of the isolate nanoshell particle red-shifts to the near-infrared region. The near-infrared super resolution images are obtained subsequently. We calculate the field intensity distribution at the different planes of imaging process using the finite element method and find that the array has super resolution imaging capability at near-infrared wavelengths. We also show that the image formation highly depends on the coherence of the dipole sources and the image-array distance.Comment: 15 pages, 6 figure

    BMPRIA mediated signaling is essential for temporomandibular joint development in mice

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    The central importance of BMP signaling in the development and homeostasis of synovial joint of appendicular skeleton has been well documented, but its role in the development of temporomandibular joint (TMJ), also classified as a synovial joint, remains completely unknown. In this study, we investigated the function of BMPRIA mediated signaling in TMJ development in mice by transgenic loss-of- and gain-of-function approaches. We found that BMPRIA is expressed in the cranial neural crest (CNC)-derived developing condyle and glenoid fossa, major components of TMJ, as well as the interzone mesenchymal cells. Wnt1-Cre mediated tissue specific inactivation of BmprIa in CNC lineage led to defective TMJ development, including failure of articular disc separation from a hypoplastic condyle, persistence of interzone cells, and failed formation of a functional fibrocartilage layer on the articular surface of the glenoid fossa and condyle, which could be at least partially attributed to the down-regulation of Ihh in the developing condyle and inhibition of apoptosis in the interzone. On the other hand, augmented BMPRIA signaling by Wnt1-Cre driven expression of a constitutively active form of BmprIa (caBmprIa) inhibited osteogenesis of the glenoid fossa and converted the condylar primordium from secondary cartilage to primary cartilage associated with ectopic activation of Smad-dependent pathway but inhibition of JNK pathway, leading to TMJ agenesis. Our results present unambiguous evidence for an essential role of finely tuned BMPRIA mediated signaling in TMJ development

    EFFECTS OF BASKETBALL SHOE ON IMPACT FORCES AND SOFT TISSUE VIBRATIONS DURING DROP JUMP AND UNEXPECTED DROP LANDING

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    The purpose of this study was to explore the effects of footwear on impact forces and soft tissue vibrations during drop jump and unexpected drop landings. Twelve male basketball players were instructed to wear two types of shoes to execute double-leg landings in each of 6 testing conditions, i.e. 2 landing styles × 3 landing heights, from a customized platform. Joint kinematics, ground reaction force, and soft tissue vibrations of the leg were collected simultaneously. The results indicated that a shoe intervention did not influence the characteristics of the impact force and soft tissue vibrations during active drop jumps. Contrarily, for the unexpected drop landings, the basketball shoe with strong cushioning properties can substantially reduced the peak impact forces as well as decreased the impact frequency and minimized the peak transmissibility
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