260 research outputs found
Rupture by damage accumulation in rocks
The deformation of rocks is associated with microcracks nucleation and
propagation, i.e. damage. The accumulation of damage and its spatial
localization lead to the creation of a macroscale discontinuity, so-called
"fault" in geological terms, and to the failure of the material, i.e. a
dramatic decrease of the mechanical properties as strength and modulus. The
damage process can be studied both statically by direct observation of thin
sections and dynamically by recording acoustic waves emitted by crack
propagation (acoustic emission). Here we first review such observations
concerning geological objects over scales ranging from the laboratory sample
scale (dm) to seismically active faults (km), including cliffs and rock masses
(Dm, hm). These observations reveal complex patterns in both space (fractal
properties of damage structures as roughness and gouge), time (clustering,
particular trends when the failure approaches) and energy domains (power-law
distributions of energy release bursts). We use a numerical model based on
progressive damage within an elastic interaction framework which allows us to
simulate these observations. This study shows that the failure in rocks can be
the result of damage accumulation
Power Laws, Precursors and Predictability During Failure
We investigate the dynamics of a modified Burridge-Knopoff model by
introducing a dissipative term to mimic the bursts of acoustic emission (AE)
from rock samples. The model explains many features of the statistics of AE
signals observed in experiments such as the crossover in the exponent value
from relatively small amplitude AE signals to larger regime, and their
dependence on the pulling speed. Significantly, we find that the cumulative
energy dissipated identified with acoustic emission can be used to predict a
major slip event. We also find a data collapse of the acoustic activity for
several major slip events describable by a universal stretched exponential with
corrections in terms of time-to-failure.Comment: 7 pages, 6 figures, Final version with minor change
Complex Fluids and Hydraulic Fracturing
Nearly 70 years old, hydraulic fracturing is a core technique for stimulating hydrocarbon production in a majority of oil and gas reservoirs. Complex fluids are implemented in nearly every step of the fracturing process, most significantly to generate and sustain fractures and transport and distribute proppant particles during and following fluid injection. An extremely wide range of complex fluids are used: naturally occurring polysaccharide and synthetic polymer solutions, aqueous physical and chemical gels, organic gels, micellar surfactant solutions, emulsions, and foams. These fluids are loaded over a wide range of concentrations with particles of varying sizes and aspect ratios and are subjected to extreme mechanical and environmental conditions. We describe the settings of hydraulic fracturing (framed by geology), fracturing mechanics and physics, and the critical role that non-Newtonian fluid dynamics and complex fluids play in the hydraulic fracturing process
A Pulsed Power Design for the Linear Inductive Accelerator Modules for the Laboratory Microfusion FA
The Light-ion Pulsed Power Induction Accelerator for the Laboratory Microfusion Facility (LMF)
In order to initiate ignition and substantial energy yield from an inertial confinement fusion target (ICF), a light-ion pulse of ~700 TW peak power and 15-20 ns duration is required. The preconceptual design presented provides this power. The HERMES-III technology of linear inductive voltage addition in a self-magnetically insulated transmission line (MITL) is utilized to generate the 25-36 MV peak voltage needed for lithium ion beams. The 15-20 MA ion current is achieved by utilizing many accelerating modules in parallel. The lithium ion beams are produced in two-stage extraction diodes. To provide the two separate voltage pulses required by the diode, a triaxial adder system is incorporated in each module. The accelerating modules are arranged symmetrically around the fusion chamber in order to provide uniform irradiation onto the ICF target. In addition, the modules are fired in a preprogrammed sequence in order to generate the optimum power pulse shape onto the target. In this paper we present an outline of the LMF accelerator conceptual design with emphasis on the architecture of the accelerating modules
The Light Ion LMF and Its Relevance to IFE
The inertial confinement fusion (ICF) program at Sandia National Laboratories (SNL) is directed toward validating light ions as an efficient driver for ICF defense and energy applications. The light ion laboratory microfusion facility (LMF) is envisioned as a facility in which high gain ICF targets could be developed and utilized in defense-related experiments. The relevance of LMF technology to eventual inertial fusion energy (IFE) applications is assessed via a comparison of LMF technologies with those projected in the Light Ion Beam Reactor Assessment (LIBRA) conceptual reactor design stud
New Pharmacological Agents to Aid Smoking Cessation and Tobacco Harm Reduction: What has been Investigated and What is in the Pipeline?
A wide range of support is available to help smokers to quit and aid attempts at harm reduction, including three first-line smoking cessation medications: nicotine replacement therapy, varenicline and bupropion. Despite the efficacy of these, there is a continual need to diversify the range of medications so that the needs of tobacco users are met. This paper compares the first-line smoking cessation medications to: 1) two variants of these existing products: new galenic formulations of varenicline and novel nicotine delivery devices; and 2) twenty-four alternative products: cytisine (novel outside of central and eastern Europe), nortriptyline, other tricyclic antidepressants, electronic cigarettes, clonidine (an anxiolytic), other anxiolytics (e.g. buspirone), selective 5-hydroxytryptamine (5-HT) reuptake inhibitors, supplements (e.g. St John’s wort), silver acetate, nicobrevin, modafinil, venlafaxine, monoamine oxidase inhibitors (MAOI), opioid antagonist, nicotinic acetylcholine receptors (nAChR) antagonists, glucose tablets, selective cannabinoid type 1 receptor antagonists, nicotine vaccines, drugs that affect gamma-aminobutyric acid (GABA) transmission, drugs that affect N-methyl-D-aspartate receptors (NMDA), dopamine agonists (e.g. levodopa), pioglitazone (Actos; OMS405), noradrenaline reuptake inhibitors, and the weight management drug lorcaserin. Six criteria are used: relative efficacy, relative safety, relative cost, relative use (overall impact of effective medication use), relative scope (ability to serve new groups of patients), and relative ease of use (ESCUSE). Many of these products are in the early stages of clinical trials, however, cytisine looks most promising in having established efficacy and safety and being of low cost. Electronic cigarettes have become very popular, appear to be efficacious and are safer than smoking, but issues of continued dependence and possible harms need to be considered
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