The oxygen affinity of haemoglobin St. Luke's

Podeu consultar la versió en castellà a:http://hdl.handle.net/11703/8763

Hemoglobin Q-Iran detected in family members from Northern Iran: a case report

<p>Abstract</p> <p>Introduction</p> <p>Hemoglobin Q-Iran (α75Asp→His) is an important member of the hemoglobin Q family, molecularly characterized by the replacement of aspartic acid by histidine. The first report of hemoglobin Q-Iran and the nomenclature of this hemoglobinopathy dates back to 1970. Iran is known as a country with a high prevalence of α- and β-thalassemia and different types of hemoglobinopathy. Many of these variants are yet to be identified as the practice of molecular laboratory techniques is limited in this part of the world. Applying such molecular methods, we report the first hemoglobin Q-Iran cases in Northern Iran.</p> <p>Case presentation</p> <p>An unusual band was detected in an isoelectric focusing test and cellulose acetate electrophoresis of a sample from a 22-year-old Iranian man from Mazandaran Province. Capillary zone electrophoresis analysis identified this band as hemoglobin Q. A similar band was also detected in his mother's electrophoresis (38 years, Iranian ethnicity). The cases underwent molecular investigation and the presence of a hemoglobin Q-Iran mutation was confirmed by the amplification refractory mutation system polymerase chain reaction method. Direct conventional sequencing revealed a single guanine to cytosine missense mutation (c.226G > C; <it>G</it>AC ><it>C</it>AC) at codon 75 in the α-globin gene in both cases.</p> <p>Conclusion</p> <p>The wide spectrum and high frequency of nondeletional α-globin mutations in Mazandaran Province is remarkable and seem to differ considerably from what has been found in Mediterranean populations. This short communication reports the first cases of patients with hemoglobin Q found in that region.</p

Miscellaneous personal letters of Alex Lachlan Williams, 1894-1897

Miscellaneous personal letters from Geoffrey J. Judge of Zeehan in regard to repairs to T. Gibbins' shop, lack of mining jobs and mines "commencing to look up" dated 1 July and 19 August 1894. From James Duncan regarding the tenancy of Williams' property at Zeehan dated 12 September 1896. From Ada Proctor of Sandy Bay on hearing ALW was about to leave Hobart to thank him for all he did for her Aunt dated 29 August 1897. From E.A Lorkin of North Lyell regarding the lease, amalgamation, and section not complying with labour clause written on 18 October 1897. From J. McDonald of Strahan, correspondence regarding mill timber and accompanying list of measurements of logs dated 6 September 1897. These personal letters of Alex Lachlan Williams 1894-1897 are from the papers of Oscar Jones, solicitor of Murdoch & Jones Queenstown branch and his predecessor Alex Lachlan Williams, apparently found at Strathelie at Broadmarsh formerly the Jones family home. The Queenstown practice was established by Alex Lachlan Williams in 1896. Later Charles Page became a partner and established an office at Zeehan. George Murdoch of the Stone Buildings, Hobart, later Murdoch and Jones, acted as Hobart agent and early in 1898 the two firms merged as Williams and Page of Hobart, Queenstown and Zeehan. In April 1899, however, Williams sold out to Murdoch and Jones, Oscar Jones managed the Queenstown branch and by July the firm's name was changed to Murdoch & Jones. Williams & Page remained in Zeehan, under C.S. Page. Private Deposit Collection M14/13 1-

Person

This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/57799Lorkin, a member of the Amalgamated Engineering Union, was a Communist activist at the Newport Railway Workshops before becoming an organizer with the AMWSU

PAPERS OF MAX LORKIN

This record was harvested from a previous catalogue system and will be withdrawn in 2025. Information in this record may be superseded or incomplete. Visit this record in UMA's new catalogue at: https://archives.library.unimelb.edu.au/nodes/view/65691Material regarding curriculum for the Victorian school of the Eureka Youth League; syllabus and constitution. Max Lorkin 'On the Path to Unity'. Notes, circulars 1956; articles on the Chinese Youth League; notes regarding culture, party and united front; extracts from Soviet Weekly 1959.113983 Consolidation: [1979.0132] "PAPERS OF MAX LORKIN

Localised population collapse of the invasive brown alga, Undaria pinnatifida: Twenty years of monitoring on Wellington's south coast

Invasive species pose a significant threat to marine environments around the world. Monitoring and research of invasive species is needed to provide direction for management programmes. This thesis is a continuation of research conducted on the invasive alga Undaria pinnatifida following its discovery on Wellington’s south coast in 1997. By compiling the results from previous monitoring surveys (1997-2000 and 2008) and carrying out additional seasonal surveys in 2018, I investigate the distribution and spread of U. pinnatifida on Wellington’s south coast, how this may have changed over time and what impacts it may have had on native macroalgal and invertebrate grazer communities. Intertidal macroalgal composition and U. pinnatifida abundance was recorded on fifteen occasions between 1997 and 2018 at two sites at Island Bay and two sites at Owhiro Bay. In addition, the subtidal abundance of six invertebrate grazers was recorded eight times within the same sampling period. Microtopography was also measured at each site to determine if topography had an influence on macroalgal composition. From 1997 to 2000 U. pinnatifida abundance gradually increased per year, but its spread remained localised to Island Bay. In 2008 U. pinnatifida had spread westward to Owhiro Bay where it was highly abundant. However, in 2018 no U. pinnatifida was recorded at any of the sites indicating a collapse of the invasion front. Further investigation revealed that U. pinnatifida was still present along the south coast with the nearest population only 500 m away from the nearest study site. The cause of the U. pinnatifida collapse is not known for certain, but it is unlikely that biotic resistance in the form of competitive exclusion or grazing or a change in environmental parameters such as temperature or nutrient concentration were contributing factors. It is speculated that the collapse arose from a multitude of confounding effects of which further research is needed to identify the exact cause. U. pinnatifida had no impact on macroalgal or grazer community composition. Additionally, microtopography also had no significant impact on macroalgal composition. This study reports the first ever invasion front collapse of U. pinnatifida in the world, and as a result, provides a new insight on U. pinnatifida distribution and invasion ecology. These findings can assist in predicting the future spread of U. pinnatifida populations as well as aid in formulation of new management strategies