1,223 research outputs found

    Economic position of the grape industry in Missouri

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    Cover title.Includes bibliographical references

    Who are our nomads today?: Deleuze's political ontology and the revolutionary problematic

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    This paper will address the question of the revolution in Gilles Deleuze's political ontology. More specifically, it will explore what kind of person Deleuze believes is capable of bringing about genuine and practical transformation. Contrary to the belief that a Deleuzian program for change centres on the facilitation of 'absolute deterritorialisation' and pure 'lines of flight', I will demonstrate how Deleuze in fact advocates a more cautious and incremental if not conservative practice that promotes the ethic of prudence. This will be achieved in part through a critical analysis of the dualistic premises upon which much Deleuzian political philosophy is based, alongside the topological triads that can also be found in his work. In light of this critique, Deleuze's thoughts on what it is to be and become a revolutionary will be brought into relief, giving rise to the question of who really is Deleuze's nomad, his true revolutionary or figure of transformation

    Matrix metalloproteinase-8 activity in gingival crevicular fluid: development of a novel assay.

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    Background and Objective: The matrix metalloproteinases (MMPs) play a role in regulating turnover and metabolism of connective tissues in health but they have also been implicated in a wide variety of pathological conditions, including periodontal disease. MMP-8 has been extensively studied in periodontal health and disease using ELISA, although this technique is limited by its inability to determine enzyme activity. The aim was to develop an assay specifically to measure MMP-8 activity and to demonstrate its use in the analysis of gingival crevicular fluid samples.Material and Methods: A specific antibody was used to coat black 96-well microtitre plates to capture MMP-8 selectively. The activity of bound MMP-8 was measured using a fluorogenic substrate. Gingival crevicular fluid samples, from healthy and periodontally diseased sites, were collected using PerioPaper strips and tested for MMP-8 activity.Results: Significantly higher MMP-8 activity was demonstrated in gingival crevicular fluid from periodontally diseased sites compared with healthy sites that exhibited basal or no MMP-8 activity. No cross-reactivity with other MMPs was noted.Conclusion: We show, for the first time, that MMP-8 activity can be specifically detected and quantified in gingival crevicular fluid samples. Measurement of MMP-8 activity could prove to be useful in monitoring periodontal disease progression

    Missouri farm prices for 25 years

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    Publication authorized February 15, 1935

    A Study to Validate a Self-Reported Version of the ONS Drug Dependence Questionnaire

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    Aim: A prospective study to establish the reliability of a self-completion version of the Office for National Statistics (ONS) questionnaire for assessing drug dependence of substance misuse clients. Method: A total of 47 treatment seeking opioid-dependent clients completed the self-complete version of the ONS questionnaire (ONS-sc) followed by the interviewer-administered ONS questionnaire (ONS-ia) at a single clinic appointment. Scores for four Class A drugs (heroin, methadone, speed and crack/cocaine) from both formats were compared. Results: The observed agreement was 87% or more and Cohen's kappa was 0.7 (p < 0.001) or more for all four Class A drugs. Sensitivity for each Class A drugs was 56% or higher and specificity was 87% or higher. Sensitivity for severe heroin dependency was 98% (CI 89–100%). There was a 100% correlation between the ONS-sc and positive urine analysis for heroin use. However, methadone and crack/cocaine drug use appeared under reported. Conclusion: ONS-sc is a feasible, practical and time-saving alternative to a detailed interview on drug dependence. Further research with a larger sample size and non-opiate-dependent clients are needed, as this could prove a useful tool for monitoring clients in everyday practice, or for survey purposes where interviews are impractical

    Graphic Views of Changes in South Dakota Agriculture

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    Because many significant changes have taken place in South Dakota agriculture in recent decades, it seems desirable to visualize what has happened. Such a backward look may be necessary in order to arrive at sound plans for today and tomorrow. Information presented in a properly constructed graph or chart can be seen at a glance and understood quite readily. Usually it takes more time to grasp the same ideas or information when presented either in written form or in a statistical table. It is to be hoped that the following graphic presentation will contribute toward a better understanding of some phases of South Dakota agriculture. Basic to the problems of any agricultural area are its soil, its climate and its population. Available and pertinent information on these subjects is presented in map, chart or graph form, with a minimum of written explanation. Historical changes in the relative size of the town and country population, land area in farms, size and number of farms, farm ownership and income are likewise visualized graphically. Maps and graphs show where the important crops are produced, trends in acreage and production, price relationships ,taxes, power, livestock numbers, etc. Changes in the financial condition of farmers are shown in graphs on loans, foreclosures, cash farm income and related data. Some of the graphs present information on a state-wide basis. Other charts and maps depict data by counties or by agricultural areas. Some maps and charts picture the situation as of a given time, whereas others show the changes that have taken place over a period of time

    Mortgage Loans on Farm Real Estate in Clark County South Dakota, 1910 - 1930

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    Purpose of Study.-This circular dealing with conditions in Clark County is part of a larger research project involving also a study of the farm mortgage situation in the counties of Brookings, Hyde, Haakon and Turner. Ever since the post-war deflation began in 1920 the farm credit problem has been more or less acute. This is an inevitable result of falling prices after a period of inflation such as that brought on by the World War. Because the bulk of the farm credit is based on real estate mortgages it has seemed particularly appropriate and timely to try to determine at this time the actual farm mortgage situation in representative areas of South Dakota. The collection of factual information about past and present farm mortgage conditions is a necessary preliminary for any plan of improvement. The immediate purpose of this study is thus to assemble all available and pertinent data respecting the farm mortgage situation in the areas studied. The ultimate purpose of the study is to bring about some improvement in prevailing conditions by the application of the relationships and principles developed. By assembling and analyzing the information as to the source of funds, amount of indebtedness, cost of credit, term of loans, volume of delinquency and of foreclosures, indebtedness per acre, etc., as these have changed during the twenty years from 1910 to 1930, some basis will be laid for recommendations aimed at the betterment of the relationship between borrower and lender and the solution of their mutual problems

    Mortgage Loans on Farm Real Estate in Haakon County, South Dakota, 1910 - 1930

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    Purpose of Study.-The unfavorable relationship between farm income and farm expense since the post-war deflation began in 1920 makes it desirable to study the farm real estate mortgage debt, as one of the important divisions of agricultural credit. The bulk of the farmer\u27s investment is in land; consequently, the method of financing that investment is an important part of the farm problem. A number of considerations are involved in the question of how to finance the ownership of farm land. Attention must be given to the value of the farm, both present and prospective, and how these values are determined. How large a loan should be placed on the farm, for what length of time should the mortgage run, what rate of interest can be paid, and how should the loan be repaid? These and a number of other important questions relating to the farm mortgage problem can be answered best only after some information has been acquired about actual conditions in a given vicinity. It is the purpose of this study to assemble and present such information with reference to Haakon County. The conditions in that county should be quite typical of the surrounding region. It is hoped that the picture of the farm mortgage situation in the area studied, as presented in the following pages, will be of help in suggesting possible improvements

    Mortgage Loans on Farm Real Estate in Turner County, South Dakota, 1910 - 1930

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    Purpose of Study. – This study of the farm mortgage situation in Turner County is a part of a larger research project including also the counties of Brookings, Clark, Haakon and Hyde. The immediate purpose has been to determine the facts with respect to the actual farm mortgage situation as revealed by the records in the office of the register of deeds. It is expected that analysis of the data will give rise to certain findings and conclusions on the basis of which recommendations can be made for the improvement of the farm mortgage conditions. Such improvements must benefit both borrowers and lenders if they are to be permanent. Thus, greater safety for the lenders should result in lower interest rates for the borrowers. If the customary loan contract does not fit present needs of farmer borrowers a modification of the terms of the contract in the interest of the mortgagors should in the long run also redound to the advantage of the mortgagees

    Mortgage Loans on Farm Real Estate in Brookings County, South Dakota

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    The purpose of this investigation in Brookings county, which is a part of a larger project including the counties of Clark, Haakon, Hyde, and Turner, is to obtain a historical picture of the changes that have taken place in the farm mortgage situation in typical areas of South Dakota. It is hope to show the sources of funds and the conditions under which farm mortgage funds have been obtained. The ultimate aim has been to discover what problems the farmers have had to face in the financing of land and buildings, and to discover and formulate principles for the safe and profitable use of land mortgage credit. Although the study has been made from the point of view of the farmer-borrower, it is obvious that no permanently satisfactory farm credit arrangement can be developed without also giving due consideration to the interests of the lender
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