665 research outputs found

    Radionuclide Imaging Evaluation of the Patient with Trauma

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    Trauma is now a major medical problem. Accidental injuries constitute the fourth leading cause of death in the United States, and the primary cause of death below the age of 37. The costs of immediate medical and surgical care, prolonged hospitalization, and lost productivity amount to several billions of dollars annually

    Molecular basis of heavy-chain class switching and switch region deletion in an Abelson virus-transformed cell line

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    We demonstrated that a subclone of an Abelson murine leukemia virus-transformed B-lymphoid cell line switched from mu to gamma 2b expression in vitro, by the classical recombination-deletion mechanism. In this line, the expressed VHDJH region and the C gamma 2b constant region gene were juxtaposed by a recombination event which linked the highly repetitive portions of the S mu and S gama 2b regions and resulted in the loss of the C mu gene from the intervening region. An additional recombination event in this subclone involved an internal deletion in the S mu region of the expressed (switched) allele. One end of this deletion occurred very close to the switch recombination point. Despite the recombination-deletion mechanism of switching, the gamma 2b-producing line retained two copies of the C mu gene and two copies of the sequence just 5' to the S gamma 2b recombination point. The possible significance of the retention of these sequences to the mechanism of class switching is discussed

    Plant capitalism and company science: the Indian career of Nathaniel Wallich

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    The career of the Danish-born botanist Nathaniel Wallich, superintendent of the Calcutta Botanic Garden from 1815 to 1846, illustrates the complex nature of botanical science under the East India Company and shows how the plant life of South Asia was used as a capital resource both in the service of the Company's economic interests and for Wallich's own professional advancement and international reputation. Rather than seeing him as a pioneer of modern forest conservation or an innovative botanist, Wallich's attachment to the ideology of ‘improvement’ and the Company's material needs better explain his longevity as superintendent of the Calcutta garden. Although aspects of Wallich's career and botanical works show the importance of circulation between Europe and India, more significant was the hierarchy of knowledge in which indigenous plant lore and illustrative skill were subordinated to Western science and in which colonial science frequently lagged behind that of the metropolis

    Edith Pechey-Phipson, M.D.: untold story.

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    Spontaneous variations in the peripheral circulation

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    Thesis (M.A.)--Boston University This item was digitized by the Internet Archive.Evidence for the nature of spontaneous variations in the peripheral circulation has been obtained from a review of the literature on the subject, supplemented by observation in the laboratory, under the direction of Professor Brenton R. Lutz, of the exposed mesentery and bladder of the frog. Contractility of the arterioles, with typical circularly arranged smooth muscle ceils and abundant sympathetic innervation, is generally accepted. The controversial point has been how important a role the capillary, with its longitudinally arranged adventitial cells and sparse sympathetic supply, plays in variations in the peripheral distribution of blood

    The Unheimlich Man‐Oeuvre

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    Peer Reviewedhttps://deepblue.lib.umich.edu/bitstream/2027.42/136524/1/ae.2001.28.4.909.pd

    Why a Universal Population-Level Approach to the Prevention of Child Abuse is Essential

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    This paper argues for the importance of adopting a population-level approach to promote more effective parenting and to reduce the risk of child maltreatment. Family-based interventions based on social learning principles have been shown to make a useful contribution in the treatment of child maltreatment. However, typically such programmes have been used to treat parents who have already become involved in the child protection system. We argue that the creation of community-wide support structures to support positive parenting is needed to reduce the prevalence of child maltreatment. Such an approach requires several criteria to be met. These include having knowledge about the prevalence rates for the targeted child outcomes sought, knowledge about the prevalence of various parenting and family risk factors, evidence that changing family risk factors reduces the prevalence of targeted problems, having culturally appropriate, cost-effective, evidence-based interventions available and making these widely accessible

    Artistic practice in Waldorf teacher education: a sensory-aesthetic concept for a digital age

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    One of the general concepts underlying Waldorf education is that teaching is an art. Although this idea is certainly not unique to Waldorf education, what is unique is the way it has been integrated into Waldorf teacher education. While Waldorf teacher education programs are diverse, both in national and international contexts, one of the central elements which they share is the prominent role which different forms of artistic practice play throughout the course of pre-service and in-service programs. This article explores the reasons and aims behind the inclusion of subjects such as music, sculpture, and speech in Waldorf teacher education, at first within the larger context of viewing different perspectives and justifications for the inclusion of the arts in teacher education outside of Waldorf pedagogy. In light of the educational challenges posed by widespread sensory deficits among children and adolescents, viewed here as being connected to the extensive role/s which different forms of digital media play in their lives, the case is made for the potentials of the arts as a way to address those deficits. In examining both the arguments for arts-based courses in teacher education and the pedagogical challenges of our times I propose a concept for the inclusion of the arts in teacher education connected to the concept of aesthesis, from the Ancient Greek concept of aisthésis, understood here as the primary perceptual-sensory basis of aesthetic experience. The integration of scientific courses with arts-based practice in teacher education is seen as providing a fruitful basis for teachers to be able to take on these educational challenges

    Reducing problem behavior during care-giving in families of preschool-aged children with developmental disabilities

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    This study evaluated two variants of a behavioral parent training program known as Stepping Stones Triple P (SSTP) using 74 preschool-aged children with developmental disabilities. Families were randomly allocated to an enhanced parent training intervention that combined parenting skills and care-giving coping skills (SSTP-E), standard parent training intervention alone (SSTP-S) or waitlist control (WL) condition. At post-intervention, both programs were associated with lower levels of observed negative child behavior, reductions in the number of care-giving settings where children displayed problem behavior, and improved parental competence and satisfaction in the parenting role as compared with the waitlist condition. Gains attained at post-intervention were maintained at 1-year follow-up. Both interventions produced significant reductions in child problem behavior, with 67% of children in the SSTP-E and 77% of children in the SSTPS showing clinically reliable change from pre-intervention to follow-up. Parents reported a high level of satisfaction with both interventions
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