Open access journals: transparent science or shady business?

OA journals consequences for Science/ The scientific community; OA journals advantages/disadvantages for the publisher/reader/author; What can be done?N/

Mouse model of Schistosomiasis: infection with Schistosoma mansoni in CD-1 mice

Schistosomiasis is a parasitic disease that affects almost 240 million worldwide. CD1 mice were infected with cercariae of S. mansoni, after which infection developed for 8 weeks. Tissues were processed to immuno-histological techniques. It was performed H&E staining for overall analyses, Sirius Red for fibrosis and immunohistochemistry for inflammation biomarkers. The most infected organ was the liver, fibrosis decreased with egg development and Galectin-3 (Gal3) and Interleukin 6 (IL-6) were expressed inside granulomasThis work was also supported by FCT – Fundação para a Ciência e Tecnologia (REF UID/BIM/04293/2013) and by the project NORTE-01-0145-FEDER-000012 and by a scholarship to Carla Luís with the reference SAICT2016/FEDER/BIO4DIA/BTI under the supervision of Dr. Rúben Fernandes.N/

Who and how should participate in health care priority setting? Evidence from a Portuguese survey

This article provides highlights of the evolution of the health care rationing debate towards a more transparent and open approach involving public participation. Discretionary models that have dominated health sector decision-making are being questioned by different sectors of society. Using data from 442 college students, we explore public’s views on its involvement in health care rationing decisions. Findings suggest that although citizens wish to be consulted, they believe doctors should play the most important role on the rationing decisions. Nonetheless, the confidence in doctors is not independent of the criteria used to support their decisions.Priorities setting, Public involvement; Explicit rationing; Health-care.

Environmental tobacco smoke risk perception and smoking behavior in Portugal

This study analyzes public attitudes towards environmental tobacco smoking (ETS) risks. ETS legislation and smoking behaviors using recent data from Special Eurobarometer 272 that is a unique database on public perception of ETS. Some major conclusions are drawn: (1) both smokers and non-smokers are aware of health consequences from ETS, (2) moderate and heavy smokers tend to be less concerned with seriousness of the health consequences, (3) that the belief that ETS increases the risk of a serious disease decreases the probability of being smoker, (4)ETS beliefs do not affect the quitting decision, (5) those who smoke at home appear to be aware of health consequences of ETS, (6) ETS health risk beliefs is negatively associated with the number of cigarette consumed.

Two-Dimensional Bosonization from Variable Shifts in the Path Integral

A method to perform bosonization of a fermionic theory in (1+1) dimensions in a path integral framework is developed. The method relies exclusively on the path integral property of allowing variable shifts, and does not depend on the explicit form of Greens functions. Two examples, the Schwinger model and the massless Thirring model, are worked out.Comment: 4 page

Asbestose pulmonar: mecanismos celulares da sua patogenia

A asbestose pulmonar continua a ser uma das doenças ocupacionais mais graves do nosso tempo. Apesar de clínica e epidemiologicamente bem caracterizada pouco se sabe ainda dos mecanismos celulares responsáveis pela sua ocorrência. Assim, a partir da informação até ao momento disponível sobre este assunto, tentámos delinear os vários mecanismos envolvidos na resposta do pulmão profundo à inalação de fibras de asbesto. Numa primeira parte caracterizam-se os vários tipos de fibras de asbesto existentes bem como os seus diferentes padrões de deposição e transporte. Numa segunda parte descrevem-se os possíveis mecanismos celulares envolvidos na patogenia da asbestose pulmonar, nomeadamente a acção dos macrófagos alveolares, dos neutrófilos e dos respectivos mediadores. A análise do perfil linfocitário de lavados bronco-alveolares de pacientes com asbestose é também descrita, salientando-se um acentuado aumento na relação CD4/CD8.Pulmonary asbestosis is still one serious occupational disease ofour times. Although the clinical and epidemiological featu res ofthe disease are well caracterized, the cellular mechanisms involved are still poorly understood. Taking advantage ofall the information available on this subject, we tried to depict the several mechanisms involved in the answer ofthe deep lung to the inhalation ofasbestos jibers. ln the jirst part ofthis article we characterized the diferent kinds ofasbestos jibers as well as their patterns oftransport and deposition in the deep lung.ln the second part we discribed the possible cellular mechanisms underlying the pathogeny of pulmonary asbestosis. The e.fJect ofthe alveolar macrophages, polinuclear neuthrophils and the action oftheir mediators is discribed. Analysis of the bronco alveolar lavage jluid lynphocitary profile of pacients with pulmonary asbestosis is also discribed, revealing significant increase in the CD4/CD8 ratio

From Metaphors to Mechanisms: Gender Sorting In(to) an Organizational Hierarchy

Numerous studies have examined patterns of gender inequality in organizational advancement, with some showing results indicative of “glass ceilings,” where gender disparities are strong at the upper reaches of the organization, while others suggest “sticky floors,” where the gender differences in advancement occur at the lower levels of the organization. These studies, however, have been less clear on the mechanisms that produce these descriptive patterns. With few exceptions, extant studies have focused on internal promotion practices and have not addressed the extent to which these patterns might reflect gender differences in external recruitment and hiring into the organization. We construct queues consisting of both external and internal candidates—the set of candidates under consideration—for over 2,200 job openings during a 27-month period for a large retail bank. We find that women are more likely than men to be hired, and that this pattern holds for jobs up and down the organizational hierarchy. The applicant pools are themselves gendered, however, with women comprising a lower percentage of the applicant pools for high-level jobs, but a greater proportion of the pools for lower-level jobs. Since women are more likely than men to advance from each applicant pool to hire at all levels of the hierarchy, the apparent “glass ceiling” observed among job incumbents is not due to gendered screening practices. Instead, the roots of gender inequality in this firm lie in the initial sorting of applicants into queues

Avaliação da resistência à ferrugem em progênies de cafeeiro F4 obtidas por cruzamentos de 'icatu' com catimor.

Com o objetivo de selecionar progênies de cafeeiro resistentes à ferrugem foram instalados e conduzidos experimentos em Três Pontas, São Sebastião do Paraíso e Machado. Foram avaliadas 17 progênies desenvolvidas pelo programa de Melhoramento Genético do Cafeeiro em Minas Gerais, coordenado pela EPAMIG e obtidas pelo cruzamento ?Icatu? x Catimor, e a cultivar Rubi MG 1192 utilizada como testemunha. O delineamento foi o de blocos casualizados com três repetições. Foram analisadas as características incidência da ferrugem no primeiro semestre de 2006.Os resultados obtidos permitem verificar que as progênies avaliadas apresentam variabilidade para a resistência a ferrugem, isso é confirmado pelas estimativas da herdabilidade que foram de boa magnitude, chegando até o valor de 92,8%. Essa condição aliada à baixa incidência da doença apresentada por algumas progênies, demonstrou que é possível selecionar progênies superiores em relação à resistência a ferrugem na população estudada