Of Higgs, Unitarity and other Questions

On the verge of conclusive checks on the Standard Model by the LHC, we discuss some of the basic assumptions. The reason for this analysis stems from a recent proposal of an Electroweak Model based on a nonlinearly realized gauge group SU(2) X U(1), where, in the perturbative approximation, there is no Higgs boson. The model enjoys the Slavnov-Taylor identities and therefore the perturbative unitarity. On the other hand, it is commonly believed that the existence of the Higgs boson is entangled with the property of unitarity, when high energy processes are considered. The argument is based mostly on the Froissart bound and on the Equivalence Theorem. In this talk we briefly review some of our objections on the validity of such arguments. Some open questions are pointed out, in particular on the limit of zero mass for the vector mesons and on the fate of the longitudinal polarizations.Comment: 23 pages, 1 figure, presented by Ruggero Ferrari at the International Conference "Gauge Fields. Yesterday, Today, Tomorrow" in honor of A.A. Slavnov. Moscow, January 19-24 201

The Wide-field High-resolution Infrared TElescope (WHITE)

The Wide-field High-resolution Infrared TElescope (WHITE) will be dedicated in the first years of its life to carrying out a few (well focused in terms of science objectives and time) legacy surveys. WHITE would have an angular resolution of ~0.3'' homogeneous over ~0.7 sq. deg. in the wavelength range 1 - 5 um, which means that we will very efficiently use all the available observational time during night time and day time. Moreover, the deepest observations will be performed by summing up shorter individual frames. We will have a temporal information that can be used to study variable objects. The three key science objectives of WHITE are : 1) A complete survey of the Magellanic Clouds to make a complete census of young stellar objects in the clouds and in the bridge and to study their star formation history and the link with the Milky Way. The interaction of the two clouds with our Galaxy might the closest example of a minor merging event that could be the main driver of galaxy evolution in the last 5 Gyrs. 2) The building of the first sample of dusty supernovae at z<1.2 in the near infrared range (1-5 um) to constrain the equation of state from these obscured objects, study the formation of dust in galaxies and build the first high resolution sample of high redshift galaxies observed in their optical frame 3) A very wide weak lensing survey over that would allow to estimate the equation of state in a way that would favourably compete with space projects.Comment: Invited talk to the 2nd ARENA Conference : "The Astrophysical Science Cases at Dome C" Potsdam 17-21 September, 200

Interference in interacting quantum dots with spin

We study spectral and transport properties of interacting quantum dots with spin. Two particular model systems are investigated: Lateral multilevel and two parallel quantum dots. In both cases different paths through the system can give rise to interference. We demonstrate that this strengthens the multilevel Kondo effect for which a simple two-stage mechanism is proposed. In parallel dots we show under which conditions the peak of an interference-induced orbital Kondo effect can be split.Comment: 8 pages, 8 figure

Effect of recombinant human nerve growth factor eye drops in patients with dry eye: a phase IIa, open label, multiple-dose study

Background: Dry eye disease (DED) affects more than 14% of the elderly population causing decrease of quality of life, high costs and vision impairment. Current treatments for DED aim at lubricating and controlling inflammation of the ocular surface. Development of novel therapies targeting different pathogenic mechanisms is sought-after. The aim of this study is to evaluate safety and efficacy of recombinant human nerve growth factor (rhNGF) eye drops in patients with DED. Methods: Forty consecutive patients with moderate to severe DED were included in a phase IIa, prospective, open label, multiple-dose, clinical trial to receive rhNGF eye drops at 20 μg/mL (Group 1: G1) or at 4 μg/mL (Group 2: G2) concentrations, two times a day in both eyes for 28 days (NCT02101281). The primary outcomes measures were treatment-emerged adverse events (AE), Symptoms Assessment in Dry Eye (SANDE) scale, ocular surface staining and Schirmer test. Results: Of 40 included patients, 39 completed the trial. Both tested rhNGF eye drop concentrations were safe and well tolerated. Twenty-nine patients experienced at least one AE (14 in G1 and 15 in G2), of which 11 had at least 1 related AE (8 in G1 and 3 in G2). Both frequency and severity of DED symptoms and ocular surface damage showed significant improvement in both groups, while tear function improved only in G1. Conclusions: The data of this study indicate that rhNGF eye drops in both doses is safe and effective in improving symptoms and signs of DED. Randomised clinical trials are ongoing to confirm the therapeutic benefit of rhNGF in DED. Trial registration number: NCT02101281

Hadronic interactions of primary cosmic rays with the FLUKA code

The measured fluxes of secondary particles produced by the interactions of cosmic rays with the astronomical environment represent a powerful tool to infer some properties of primary cosmic rays. In this work we investigate the production of secondary particles in inelastic hadronic interactions between several cosmic rays species of projectiles and different target nuclei of the interstellar medium. The yields of secondary particles have been calculated with the FLUKA simulation package, that provides with very good accuracy the energy distributions of secondary products in a large energy range. An application to the propagation and production of secondaries in the Galaxy is presented.Comment: 8 pages, 4 figures; Contribution to the 34th International Cosmic Ray Conference, July 30 to August 6, The Hague, Netherlands; fixing a typo in the y-axis label of Fig.

Effect of ELF e.m. fields on metalloprotein redox-active sites

The peculiarity of the distribution and geometry of metallic ions in enzymes pushed us to set the hypothesis that metallic ions in active-site act like tiny antennas able to pick up very feeble e.m. signals. Enzymatic activity of Cu2+, Zn2+ Superoxide Dismutase (SOD1) and Fe2+ Xanthine Oxidase (XO) has been studied, following in vitro generation and removal of free radicals. We observed that Superoxide radicals generation by XO is increased by a weak field having the Larmor frequency fL of Fe2+ while the SOD1 kinetics is sensibly reduced by exposure to a weak field having the frequency fL of Cu2+ ion.Comment: 18 pages, 4 figure

On Abelian Multi-Chern-Simons Field Theories

In this paper a class of multi-Chern-Simons field theories which is relevant to the statistical mechanics of polymer systems is investigated. Motivated by the problems which one encounters in the treatment of these theories, a general procedure is presented to eliminate the Chern-Simons fields from their action. In this way it has been possible to derive an expression of the partition function of topologically linked polymers which depends explicitly on the topological numbers and does not have intractable nonlocal terms as it happened in previous approaches. The new formulation of multi-Chern-Simons field theories is then used to remove and clarify some inconsistencies and ambiguities which apparently affect field theoretical models of topologically linked polymers. Finally, the limit of disentangled polymers is discussed.Comment: 18 pages, plain LaTe

Glueball operators and the microscopic approach to N=1 gauge theories

We explain how to generalize Nekrasov's microscopic approach to N=2 gauge theories to the N=1 case, focusing on the typical example of the U(N) theory with one adjoint chiral multiplet X and an arbitrary polynomial tree-level superpotential Tr W(X). We provide a detailed analysis of the generalized glueball operators and a non-perturbative discussion of the Dijkgraaf-Vafa matrix model and of the generalized Konishi anomaly equations. We compute in particular the non-trivial quantum corrections to the Virasoro operators and algebra that generate these equations. We have performed explicit calculations up to two instantons, that involve the next-to-leading order corrections in Nekrasov's Omega-background.Comment: 38 pages, 1 figure and 1 appendix included; v2: typos and the list of references corrected, version to appear in JHE