898 research outputs found

    Breast cancer cells exploit mitophagy to exert therapy resistance

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    Extracting Scattering Phase-Shifts in Higher Partial-Waves from Lattice QCD Calculations

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    L\"uscher's method is routinely used to determine meson-meson, meson-baryon and baryon-baryon s-wave scattering amplitudes below inelastic thresholds from Lattice QCD calculations - presently at unphysical light-quark masses. In this work we review the formalism and develop the requisite expressions to extract phase-shifts describing meson-meson scattering in partial-waves with angular-momentum l<=6 and l=9. The implications of the underlying cubic symmetry, and strategies for extracting the phase-shifts from Lattice QCD calculations, are presented, along with a discussion of the signal-to-noise problem that afflicts the higher partial-waves.Comment: 79 pages, 41 figure

    The pion-pion Interaction in the rho Channel in Finite Volume

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    The aim of this paper is to investigate an efficient strategy that allows to obtain pi-pi phase shifts and rho meson properties from QCD lattice data with high precision. For this purpose we evaluate the levels of the pi-pi system in the rho channel in finite volume using chiral unitary theory. We investigate the dependence on the pi mass and compare with other approaches which use QCD lattice calculations and effective theories. We also illustrate the errors induced by using the conventional Luscher approach instead of a more accurate one recently developed that takes into account exactly the relativistic two meson propagators. Finally we make use of this latter approach to solve the inverse problem, getting pi-pi phase shifts from "synthetic" lattice data, providing an optimal strategy and showing which accuracy is needed in these data to obtain the ρ\rho properties with a desired accuracy.Comment: 16 pages, 13 figures, 1 table, substantially modified with practical examples of use to lattice researchers, new comments and references adde

    Experimental quantum tossing of a single coin

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    The cryptographic protocol of coin tossing consists of two parties, Alice and Bob, that do not trust each other, but want to generate a random bit. If the parties use a classical communication channel and have unlimited computational resources, one of them can always cheat perfectly. Here we analyze in detail how the performance of a quantum coin tossing experiment should be compared to classical protocols, taking into account the inevitable experimental imperfections. We then report an all-optical fiber experiment in which a single coin is tossed whose randomness is higher than achievable by any classical protocol and present some easily realisable cheating strategies by Alice and Bob.Comment: 13 page

    An evidence review of research on health interventions in humanitarian crises. Final Report

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    This review was conducted to provide a rigorous assessment of the current quality and depth of the evidence-base that informs humanitarian public health programming globally. It assesses the quantity and quality of intervention studies, rather than measuring the actual effectiveness of the intervention itself. The review addresses evidence on interventions in humanitarian crises (including early recovery and forced displacement) for health topics of: communicable disease control water, sanitation and hygiene (WASH) nutrition sexual and reproductive health (SRH), including gender-based violence (GBV) mental health and psychosocial support non-communicable disease (NCD) injury and physical rehabilitation health services health systems. In addition, contextual factors influencing the delivery of health-related interventions are included in the project, consisting of: * access to health services * health assessment methods * coordination * accountability * health worker security * urbanisation. The evidence review used the following two main methods: (i) A series of systematic literature reviews on evidence of humanitarian interventions related to the health topics and on the influence of contextual factors on the interventions. The systematic review on evidence of interventions for the different health topics included quantitative evidence from published and grey literature. The systematic review on the contextual factors included quantitative and qualitative evidence from the published literature. Standard systematic review methodologies were used. (ii) Qualitative individual interviews with expert practitioners, policy makers and academics to identify critical weaknesses and gaps in the evidence base for humanitarian public health actions (including related to the contextual factors) and to recommend priority areas for further research. A series of more general consultations with humanitarian health experts through meetings in London, Geneva, Paris, and New York

    Urban agriculture: a global analysis of the space constraint to meet urban vegetable demand

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    Urban agriculture (UA) has been drawing a lot of attention recently for several reasons: the majority of the world population has shifted from living in rural to urban areas; the environmental impact of agriculture is a matter of rising concern; and food insecurity, especially the accessibility of food, remains a major challenge. UA has often been proposed as a solution to some of these issues, for example by producing food in places where population density is highest, reducing transportation costs, connecting people directly to food systems and using urban areas efficiently. However, to date no study has examined how much food could actually be produced in urban areas at the global scale. Here we use a simple approach, based on different global-scale datasets, to assess to what extent UA is constrained by the existing amount of urban space. Our results suggest that UA would require roughly one third of the total global urban area to meet the global vegetable consumption of urban dwellers. This estimate does not consider how much urban area may actually be suitable and available for UA, which likely varies substantially around the world and according to the type of UA performed. Further, this global average value masks variations of more than two orders of magnitude among individual countries. The variations in the space required across countries derive mostly from variations in urban population density, and much less from variations in yields or per capita consumption. Overall, the space required is regrettably the highest where UA is most needed, i.e., in more food insecure countries. We also show that smaller urban clusters (i.e., <100 km2 each) together represent about two thirds of the global urban extent; thus UA discourse and policies should not focus on large cities exclusively, but should also target smaller urban areas that offer the greatest potential in terms of physical space

    Methods for removal of unwanted signals from gravity time-series : comparison using linear techniques complemented with analysis of system dynamics

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    We thanks the participants of the 35th General Assembly of the European Seismological Commission for comments on preliminary results. The authors are grateful to all IGETS contributors, particularly to the station operators and to ISDC/GFZ-Potsdam for providing the original gravity data used in this study. We also thank the developers of ATLANTIDA3.1 and UTide. Part of this work was performed using the ICSMB High Performance Computing Cluster, University of Aberdeen. We also thanks M. Thiel and A. Moura for reviewing a preliminary version and making comments on the methods section and M.A. Ara´ujo for comments on Lyapunov exponents. Funding: A. Valencio is supported by CNPq, Brazil [206246/2014-5]; and received a travel grant from the School of Natural and Computing Sciences, University of Aberdeen [PO2073498], for a presentation including preliminary results.Peer reviewedPostprintPublisher PD

    Hidden charm molecules in finite volume

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    In the present paper we address the interaction of pairs of charmed mesons with hidden charm in a finite box. We use the interaction from a recent model based on heavy-quark spin symmetry that predicts molecules of hidden charm in the infinite volume. The energy levels in the box are generated within this model, and from them some synthetic data are generated. These data are then employed to study the inverse problem of getting the energies of the bound states and phase shifts for D (D) over bar or D*(D) over bar*. Different strategies are investigated using the lowest two levels for different values of the box size, and the errors produced are studied. Starting from the upper level, fits to the synthetic data are carried out to determine the scattering length and effective range plus the binding energy of the ground state. A similar strategy using the effective range formula is considered with a simultaneous fit to the two levels-one above and the other one below the threshold. This method turns out to be more efficient than the previous one. Finally, a method based on the fit to the data by means of a potential and a conveniently regularized loop function, turns out to be very efficient and allows us to produce accurate results in the infinite volume starting from levels of the box with errors far larger than the uncertainties obtained in the final results. A regularization method based on Gaussian wave functions turns out to be rather efficient in the analysis and as a byproduct a practical and fast method to calculate the Luscher function with high precision is presented

    Domain wall QCD with physical quark masses

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    We present results for several light hadronic quantities (fπf_\pi, fKf_K, BKB_K, mudm_{ud}, msm_s, t01/2t_0^{1/2}, w0w_0) obtained from simulations of 2+1 flavor domain wall lattice QCD with large physical volumes and nearly-physical pion masses at two lattice spacings. We perform a short, O(3)%, extrapolation in pion mass to the physical values by combining our new data in a simultaneous chiral/continuum `global fit' with a number of other ensembles with heavier pion masses. We use the physical values of mπm_\pi, mKm_K and mΩm_\Omega to determine the two quark masses and the scale - all other quantities are outputs from our simulations. We obtain results with sub-percent statistical errors and negligible chiral and finite-volume systematics for these light hadronic quantities, including: fπf_\pi = 130.2(9) MeV; fKf_K = 155.5(8) MeV; the average up/down quark mass and strange quark mass in the MSˉ\bar {\rm MS} scheme at 3 GeV, 2.997(49) and 81.64(1.17) MeV respectively; and the neutral kaon mixing parameter, BKB_K, in the RGI scheme, 0.750(15) and the MSˉ\bar{\rm MS} scheme at 3 GeV, 0.530(11).Comment: 131 pages, 30 figures. Updated to match published versio
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