845 research outputs found
Southern Chesapeake Bay water color and circulation analysis
There are no author-identified significant results in this report
Phase Transitions in a Dusty Plasma with Two Distinct Particle Sizes
In semiconductor manufacturing, contamination due to particulates
significantly decreases the yield and quality of device fabrication, therefore
increasing the cost of production. Dust particle clouds can be found in almost
all plasma processing environments including both plasma etching devices and in
plasma deposition processes. Dust particles suspended within such plasmas will
acquire an electric charge from collisions with free electrons in the plasma.
If the ratio of inter-particle potential energy to the average kinetic energy
is sufficient, the particles will form either a liquid structure with short
range ordering or a crystalline structure with long range ordering. Otherwise,
the dust particle system will remain in a gaseous state. Many experiments have
been conducted over the past decade on such colloidal plasmas to discover the
character of the systems formed, but more work is needed to fully understand
these structures. The preponderance of previous experiments used monodisperse
spheres to form complex plasma systems
Dusty Plasma Correlation Function Experiment
Dust particles immersed within a plasma environment, such as those in
protostellar clouds, planetary rings or cometary environments, will acquire an
electric charge. If the ratio of the inter-particle potential energy to the
average kinetic energy is high enough the particles will form either a "liquid"
structure with short-range ordering or a crystalline structure with long range
ordering. Many experiments have been conducted over the past several years on
such colloidal plasmas to discover the nature of the crystals formed, but more
work is needed to fully understand these complex colloidal systems. Most
previous experiments have employed monodisperse spheres to form Coulomb
crystals. However, in nature (as well as in most plasma processing
environments) the distribution of particle sizes is more randomized and
disperse. This paper reports experiments which were carried out in a GEC rf
reference cell modified for use as a dusty plasma system, using varying sizes
of particles to determine the manner in which the correlation function depends
upon the overall dust grain size distribution. (The correlation function
determines the overall crystalline structure of the lattice.) Two dimensional
plasma crystals were formed of assorted glass spheres with specific size
distributions in an argon plasma. Using various optical techniques, the pair
correlation function was determined and compared to those calculated
numerically.Comment: 6 pages, Presented at COSPAR '0
Nonlinear vertical oscillations of a particle in a sheath of a rf discharge
A new simple method to measure the spatial distribution of the electric field
in the plasma sheath is proposed. The method is based on the experimental
investigation of vertical oscillations of a single particle in the sheath of a
low-pressure radio-frequency discharge. It is shown that the oscillations
become strongly nonlinear and secondary harmonics are generated as the
amplitude increases. The theory of anharmonic oscillations provides a good
qualitative description of the data and gives estimates for the first two
anharmonic terms in an expansion of the sheath potential around the particle
equilibrium.Comment: 11 pages, 4 figure
A Comprehensive Archival Search for Counterparts to Ultra-Compact High Velocity Clouds: Five Local Volume Dwarf Galaxies
We report five Local Volume dwarf galaxies (two of which are presented here
for the first time) uncovered during a comprehensive archival search for
optical counterparts to ultra-compact high velocity clouds (UCHVCs). The UCHVC
population of HI clouds are thought to be candidate gas-rich, low mass halos at
the edge of the Local Group and beyond, but no comprehensive search for stellar
counterparts to these systems has been presented. Careful visual inspection of
all publicly available optical and ultraviolet imaging at the position of the
UCHVCs revealed six blue, diffuse counterparts with a morphology consistent
with a faint dwarf galaxy beyond the Local Group. Optical spectroscopy of all
six candidate dwarf counterparts show that five have an H-derived
velocity consistent with the coincident HI cloud, confirming their association,
the sixth diffuse counterpart is likely a background object. The size and
luminosity of the UCHVC dwarfs is consistent with other known Local Volume
dwarf irregular galaxies. The gas fraction () of the five
dwarfs are generally consistent with that of dwarf irregular galaxies in the
Local Volume, although ALFALFA-Dw1 (associated with ALFALFA UCHVC
HVC274.68+74.70123) has a very high 40. Despite the
heterogenous nature of our search, we demonstrate that the current dwarf
companions to UCHVCs are at the edge of detectability due to their low surface
brightness, and that deeper searches are likely to find more stellar systems.
If more sensitive searches do not reveal further stellar counterparts to
UCHVCs, then the dearth of such systems around the Local Group may be in
conflict with CDM simulations.Comment: 18 pages, 4 tables, 4 figures, ApJ Accepte
Transcriptional Signatures of Brain Aging and Alzheimer\u27s Disease: What Are Our Rodent Models Telling Us?
Aging is the biggest risk factor for idiopathic Alzheimer’s disease (AD). Recently, the National Institutes of Health released AD research recommendations that include: appreciating normal brain aging, expanding data-driven research, using open-access resources, and evaluating experimental reproducibility. Transcriptome data sets for aging and AD in humans and animal models are available in NIH-curated, publically accessible databases. However, little work has been done to test for concordance among those molecular signatures. Here, we test the hypothesis that brain transcriptional profiles from animal models recapitulate those observed in the human condition. Raw transcriptional profile data from twenty-nine studies were analyzed to produce p-values and fold changes for young vs. aged or control vs. AD conditions. Concordance across profiles was assessed at three levels: (1) # of significant genes observed vs. # expected by chance; (2) proportion of significant genes showing directional agreement; (3) correlation among studies for magnitude of effect among significant genes. The highest concordance was found within subjects across brain regions. Normal brain aging was concordant across studies, brain regions, and species, despite profound differences in chronological aging among humans, rats and mice. Human studies of idiopathic AD were concordant across brain structures and studies, but were not concordant with the transcriptional profiles of transgenic AD mouse models. Further, the five transgenic AD mouse models that were assessed were not concordant with one another. These results suggest that normal brain aging is similar in humans and research animals, and that different transgenic AD model mice may reflect selected aspects of AD pathology
Risks Involved in the Use of Enrofloxacin for Salmonella Enteritidis or Salmonella Heidelberg in Commercial Poultry
The objectives of the present study were to evaluate the risks involved in the use of Enrofloxacin for Salmonella Enteritidis (SE) or Salmonella Heidelberg (SH) in commercial poultry and determine the effects of a probiotic as an antibiotic alternative. Two experiments were conducted to evaluate the risks involved in the use of Enrofloxacin for SE or SH in commercial poultry. Exp 1 consisted of 2 trials. In each trial, chickens were assigned to one of three groups; control + SE challenged; Enrofloxacin 25 mg/kg + SE; Enrofloxacin 50 mg/kg + SE. Chickens received Enrofloxacin in the drinking water from days 1 to 5 of age. On day 6, all groups received fresh water without any treatment. All chickens were orally gavaged with 107 cfu/chick of SE at 7 days of age and euthanized on 8 days of age. In Exp 2, turkey poults were assigned to one of the three groups; control + SH; probiotic + SH; Enrofloxacin 50 mg/kg + SH. Poults received probiotic or Enrofloxacin in the drinking water from days 1 to 5 of age. On day 6, poults received fresh water without any treatment. Poults were orally gavaged with 107 cfu/poult of SH at 7 days of age. Poults were weighted and humanely killed 24 h post-SH challenge to evaluate serum concentration of FITC-D to evaluate intestinal permeability, metagenomics and SH infection. In both trials of Exp 1, chickens treated with Enrofloxacin were more susceptible to SE organ invasion and intestinal colonization when compared with control non-treated chickens (P < 0.05). In Exp 2, poults treated with 50 mg/kg of Enrofloxacin showed an increase in body weight, however, this group also showed an increase in SH susceptibility, intestinal permeability and lower proportion of Firmicutes and Bacteroidetes, but with control group had the highest proportion of Proteobacteria. In contrast, poults that received the probiotic had the highest proportion of Firmicutes and Bacteroidetes, but lowest Proteobacteria. The results of the present study suggest that prophylactic utilization of Enrofloxacin at 5 times the recommended dose in poultry, increases the susceptibility to salmonellae infections, and confirms probiotics may be a
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