Zero--Temperature Quantum Phase Transition of a Two--Dimensional Ising Spin--Glass

We study the quantum transition at $T=0$ in the spin-$\frac12$ Ising spin--glass in a transverse field in two dimensions. The world line path integral representation of this model corresponds to an effective classical system in (2+1) dimensions, which we study by Monte Carlo simulations. Values of the critical exponents are estimated by a finite-size scaling analysis. We find that the dynamical exponent, $z$, and the correlation length exponent, $\nu$, are given by $z = 1.5 \pm 0.05$ and $\nu = 1.0 \pm 0.1$. Both the linear and non-linear susceptibility are found to diverge at the critical point.Comment: RevTeX 10 pages + 4 figures (appended as uuencoded, compressed tar-file), THP21-9

Random bond Ising chain in a transverse magnetic field: A finite-size scaling analysis

We investigate the zero-temperature quantum phase transition of the random bond Ising chain in a transverse magnetic field. Its critical properties are identical to those of the McCoy-Wu model, which is a classical Ising model in two dimensions with layered disorder. The latter is studied via Monte Carlo simulations and transfer matrix calculations and the critical exponents are determined with a finite-size scaling analysis. The magnetization and susceptibility obey conventional rather than activated scaling. We observe that the order parameter-- and correlation function--probability distribution show a nontrivial scaling near the critical point which implies a hierarchy of critical exponents associated with the critical behavior of the generalized correlation lengths.Comment: RevTeX 13 pages + 4 figures (appended as uuencoded compressed tar-file), THP61-9

Common trends in the critical behavior of the Ising and directed walk models

We consider layered two-dimensional Ising and directed walk models and show that the two problems are inherently related. The information about the zero-field thermodynamical properties of the Ising model is contained into the transfer matrix of the directed walk. For several hierarchical and aperiodic distributions of the couplings, critical exponents for the two problems are obtained exactly through renormalization.Comment: 4 pages, RevTeX file + 1 figure, epsf needed. To be published in PR

Orexin Receptor Antagonism, a New Sleep-Enabling Paradigm: A Proof-of-Concept Clinical Trial

Peer reviewe

Volume 03

Introduction from Dean Dr. Charles Ross Little Shop of Horrors by Longwood Theater Department Who Has the Hottest Hotsauce in Farmville: A Quantitative Comparison of Sauces from Local Restaurants by Cheryl Peck and Charles Hoever Precipitation Effects on the Growth of White Oaks and Virginia Pines on the Mt. Vernon Plantation by Brittany Anderson Design and Synthesis of Novel Ion Binding Molecules for Self-Assembly and Sensing Applications by J. Ervin Sheldon A Statistical Analysis of Algorithms for Playing SameGame by Richard Hayden Intersecting Cylinders at Arbitrary Angles by Yuri Calustro Putting a Foot in the Revolving Door: Strategies for Reducing Teacher Attrition by Candice Fleming and Rebecca Franklin The Effect of Presentation on Spanish Vocabulary Recall by Ashley Yocum How Attractive Are You? Individuals Sensitivity to Number of Sexual Partners by Danielle M. Jagoda and Cristina M. Valdivieso Culturally Relevant Practices for Teaching Code-Switching to African-American Students in Kindergarten Classrooms by Jameka Jones Two Poems – “Dust” and “Check Out Girls” by Amy Ellis Three Poems – “Rosewood Massacre, 1923”, “Jarring” and “Reverence” by Ashley Maser Three Poems – “Dirty Thunderstorm”, “Summer Hide \u27N Seek Car Tag” and “Bliss” by Erikk Shupp Analysis of the Wilton Diptych by Jamie Yurasits “Nod”, “Corriline” “Flying” “Familiar” by Alexander Leonhart Papermaking by Kenny Wolfe and Sally Meadows “Plant” by J. Haley, Amy Jackson, and Morgan Howard “Dare to Dart” by Amy Jackson, Adrienne Heinbaugh and Melissa Dorton Untitled Photographs by Hopson “Lockets” by Morgan Howard Graphic Designs and Untitled Photographs by Ciarra Stalker Selections from a Senior Recital by Joshua Davi

Glycyrrhizin Exerts Antioxidative Effects in H5N1 Influenza A Virus-Infected Cells and Inhibits Virus Replication and Pro-Inflammatory Gene Expression

Glycyrrhizin is known to exert antiviral and anti-inflammatory effects. Here, the effects of an approved parenteral glycyrrhizin preparation (Stronger Neo-Minophafen C) were investigated on highly pathogenic influenza A H5N1 virus replication, H5N1-induced apoptosis, and H5N1-induced pro-inflammatory responses in lung epithelial (A549) cells. Therapeutic glycyrrhizin concentrations substantially inhibited H5N1-induced expression of the pro-inflammatory molecules CXCL10, interleukin 6, CCL2, and CCL5 (effective glycyrrhizin concentrations 25 to 50 µg/ml) but interfered with H5N1 replication and H5N1-induced apoptosis to a lesser extent (effective glycyrrhizin concentrations 100 µg/ml or higher). Glycyrrhizin also diminished monocyte migration towards supernatants of H5N1-infected A549 cells. The mechanism by which glycyrrhizin interferes with H5N1 replication and H5N1-induced pro-inflammatory gene expression includes inhibition of H5N1-induced formation of reactive oxygen species and (in turn) reduced activation of NFκB, JNK, and p38, redox-sensitive signalling events known to be relevant for influenza A virus replication. Therefore, glycyrrhizin may complement the arsenal of potential drugs for the treatment of H5N1 disease