Landsat : water quality surveillance of Roodeplaat Dam

Bibliography: pages 104-118.The need for accurate, synoptic, up to date information, concerning the quality of South African impoundments, prompted a study into the relationship between Landsat reflectance data and chlorophyll ~ and turbidity in Roodeplaat Dam. Surface and integrated chlorophyll a as well as surface and integrated turbidity were collected simultaneously with the satellite's overpass, from 32 sampling sites on the impoundment. Six days, between 81.10 .14 and 82 .11.16, were cloud free and the data were analysed in order to establish the relationship between the specific water quality conditions and the satellite reflectance data. Prior to the analysis certain factors required attention. Firstly, it was important to accurately align the sampling sites with their corresponding Landsat pixels. Secondly, the satellite reflectance data were corrected for influences of haze and the angle of the sun. Thirdly, the requirement that the water quality surface reference data be representative of the range of conditions in the impoundment was recognised. Lastly, the interrelationship between chlorophyll a and turbidity and the multicollinearity evident between the four reflectance bands, demanded that a multi-variate statistical technique be implemented, in order to adequately analyse the available data

Management of patients with persistent medically unexplained symptoms: a descriptive study

Background: In 2013 the Dutch guideline for management of medically unexplained symptoms (MUS) was published. The aim of this study is to assess medical care for patients with persistent MUS as recorded in their electronic medical records, to investigate if this is in line with the national guideline for persistent MUS and whether there are changes in care over time. Methods: We conducted an observational study of adult primary care patients with MUS. Routinely recorded health care data were extracted from electronic medical records of patients participating in an ongoing randomised controlled trial in 30 general practices in the Netherlands. Data on general practitioners’ (GPs’) management strategies during MUS consultations were collected in a 5-year period for each patient prior. Management strategies were categorised according to the options offered in the Dutch guideline. Changes in management over time were analysed. Results: Data were collected from 1035 MUS consultations (77 patients). Beside history-taking, the most frequently used diagnostic strategies were physical examination (24.5%) and additional investigations by the GP (11.1%). Frequently used therapeutic strategies were prescribing medication (24.6%) and providing explanations (11.2%). As MUS symptoms persisted, GPs adjusted medication, discussed progress and scheduled follow-up appointments more frequently. The least frequently used strategies were exploration of all complaint dimensions (i.e. somatic, cognitive, emotional, behavioural and social) (3.5%) and referral to a psychologist (0.5%) or psychiatrist (0.1%). Conclusions: Management of Dutch GPs is partly in line with the Dutch guideline. Medication was possibly prescribed more frequently than recommended, whereas exploration of all complaint dimensions, shared problem definition and referral to mental health care were used less

Pheasants in Asia 1982: Proceedings of the Second International Pheasant Symposium (September 1982 : Srinagar, Kashmir)

Chapter 1: Pheasant Conservation in India and Nepal Conservation of pheasants in India through biosphere reserves, N. D. Jayal Pheasant conservation in Nepal, BISWA N. UPRETI The Machhapuchare Wildlife Conservation Project in Nepal, James Roberts Planning for the management of a Himalayan pheasant reserve, J. A. Forster The role of mapping in future management and conservation of pheasants, Christopher D. W. Savage Chapter 2: Population Studies of Himalayan Pheasants Surveys, census, monitoring and research: Their role in pheasant conservation, A. J . GASTON Popluation dynamics of the Koklas pheasant (Pucrasia macolopha) in Malkandi Forests, Pakistan, Wazir Mohammad Khan and Iqmail Hussain Shah Status and distribution of the western tragopan in northeastern Pakistan, Kamal Islam Pheasant census survey of Kashmir Valley: A report, B. S. Lambda et al. Nepal-Himalaya pheasant surveys ay Pipar, Macchapucahre, Pralad B. Yonzon Survey of cheer pheasants near Dhorpatan, west Nepal, 1981, A. D. Lelliott Chapter 3: Pheasant Distribution and Status Maps of recent pheasant observations in the Himalayas, A. J. Gaston Population survey of the pheasant Phasianus colchicus in Iran, Jamshid Mansoori Pheasants and quail in Bangladesh, Fazlul Karim Pheasants of Skkim, P. O. Pazo New measures to protect the pheasants of Nagaland, D. K. Zeilang Recent pheasant surveys in peninsular Malaysia, G. W. H. Davison and K. W. Scriven Thailand\u27s rarest pheasant, Lophura nycthermera lewisi, Somtob Norapuck Chapter 4: Pheasant Biology and Habitat Conservation of pheasant habitat in Asia and a possible role for hunters and aviculturists, G. R. Potts The relevance of social organisation to conservation in pheasants, M. W. Ridley Patterns of summer habitat use by Himalayan snowcock (Tetraogallus himalayensis) in Nevada, U.S.A., James D. Bland Ecology and behaviour of great argus in sub-optimal habitat, G. W .H. Davison Chapter 5: Pheasant Aviculture and Re-introductions Pheasant aviculture and its role in conservation, Keith C. R. Howman and Charles Sivelle Some problems associated with pheasant aviculture in a tropical climate Kr. Suresh Singh and Kr. Raghavendra Singh Experience in partridge rearing, Keith Chalmers-Watson Report on Cheer Pheasant Re-introduction Project, Pakistan M. W. Ridley and Kamal Islam Resolutions and Recommendations List of Participant

Mate value discrepancy and attachment anxiety predict the perpetration of digital dating abuse

Research suggests that individual differences in attachment style predict the perpetration of digital dating abuse. In addition to attachment style, no research, to our knowledge, has explored the role of mate value in the perpetration of digital dating abuse. In this paper, we argue that digital dating abuse is a contemporary cost-inflicting mate retention behaviour, where larger mate value discrepancies between partners are associated with higher levels of digital dating abuse (n = 167). As expected, high mate value discrepancy and attachment anxiety were associated with high levels of digital dating abuse. We provide novel support for the relationship between mate value discrepancy and digital dating abuse. Our findings provide support for additional, unexplored factors which lead to the perpetration of digital dating abus

Does undertaking an intercalated BSc influence first clinical year exam results at a London medical school?

Background: Intercalated BScs (iBScs) are an optional part of the medical school curriculum in many Universities. Does undertaking an iBSc influence subsequent student performance? Previous studies addressing this question have been flawed by iBSc students being highly selected. This study looks at data from medical students where there is a compulsory iBSc for non-graduates. Our aim was to see whether there was any difference in performance between students who took an iBSc before or after their third year (first clinical year) exams.Methods: A multivariable analysis was performed to compare the third year results of students at one London medical school who had or had not completed their iBSc by the start of this year (n = 276). A general linear model was applied to adjust for differences between the two groups in terms of potential confounders (age, sex, nationality and baseline performance).Results: The results of third year summative exams for 276 students were analysed (184 students with an iBSc and 92 without). Unadjusted analysis showed students who took an iBSc before their third year achieved significantly higher end of year marks than those who did not with a mean score difference of 4.4 (0.9 to 7.9 95% CI, p = 0.01). (overall mean score 238.4 "completed iBSc" students versus 234.0 "not completed", range 145.2 - 272.3 out of 300). There was however a significant difference between the two groups in their prior second year exam marks with those choosing to intercalate before their third year having higher marks. Adjusting for this, the difference in overall exam scores was no longer significant with a mean score difference of 1.4 (-4.9 to +7.7 95% CI, p = 0.66). (overall mean score 238.0 "completed iBSc" students versus 236.5 "not completed").Conclusions: Once possible confounders are controlled for (age, sex, previous academic performance) undertaking an iBSc does not influence third year exam results. One explanation for this confounding in unadjusted results is that students who do better in their second year exams are more likely to take an iBSc before their third year

An MRD-stratified pediatric protocol is as deliverable in adolescents and young adults as in children with ALL

Pediatric regimens have improved outcomes in adolescent and young adult (AYA) acute lymphoblastic leukemia (ALL). However, results remain inferior to children with ALL. The Australasian Leukaemia and Lymphoma Group (ALLG) ALL06 study (anzctr.org.au/ ACTRN12611000814976) was designed to assess whether a pediatric ALL regimen (Australian and New Zealand Children’s Haematology and Oncology Group [ANZCHOG] Study 8) could be administered to patients aged 15 to 39 years in a comparable time frame to children as assessed by the proportion of patients completing induction/ consolidation and commencing the next phase of therapy (protocol M or high-risk [HR] treatment) by day 94. Minimal residual disease (MRD) response stratified patients to HR treatment and transplantation. From 2012 to 2018, a total of 86 patients were enrolled; 82 were eligible. Median age was 22 years (range, 16-38 years). Induction/consolidation was equally deliverable in ALL06 as in Study 8. In ALL06, 41.5% (95% confidence interval [CI], 30.7-52.9) commenced protocol M or HR therapy by day 94 vs 39.3% in Study 8 (P = .77). Median time to protocol M/HR treatment was 96 days (interquartile range, 87.5-103 days) in ALL06 vs 98 days in Study 8 (P = .80). Induction mortality was 3.6%. With a median follow-up of 44 months (1-96 months), estimated 3-year disease-free survival was 72.8% (95% CI, 62.8-82.7), and estimated 3-year overall survival was 74.9% (95% CI, 65.3-84.5). End induction/consolidation MRD negativity rate was 58.6%. Body mass index ≥30 kg/m2 and day 79 MRD positivity were associated with poorer disease-free survival and overall survival. Pediatric therapy was safe and as deliverable in AYA patients as in children with ALL. Intolerance of pediatric ALL induction/consolidation is not a major contributor to inferior outcomes in AYA ALL

Inflammatory and haematological markers in the maternal, umbilical cord and infant circulation in histological chorioamnionitis

BACKGROUND: The relationship between histological chorioamnionitis and haematological and biochemical markers in mothers and infants at delivery, and in infants postnatally, is incompletely characterised. These markers are widely used in the diagnosis of maternal and neonatal infection. Our objective was to investigate the effects of histological chorioamnionitis (HCA) on haematological and biochemical inflammatory markers in mothers and infants at delivery, and in infants post-delivery. METHODS: Two hundred and forty seven mothers, delivering 325 infants, were recruited at the only tertiary perinatal centre in Western Australia. Placentae were assessed for evidence of HCA using a semi-quantitative scoring system. Maternal high sensitivity C-reactive protein (hsCRP), procalcitonin, and umbilical cord hsCRP, procalcitonin, white cell count and absolute neutrophil count were measured at delivery. In infants where sepsis was clinically suspected, postnatal CRP, white cell count and absolute neutrophil count were measured up to 48 hours of age. The effect of HCA on maternal, cord and neonatal markers was evaluated by multivariable regression analysis. RESULTS: The median gestational age was 34 weeks and HCA was present in 26 of 247 (10.5%) placentae. Mothers whose pregnancies were complicated by HCA had higher hsCRP (median 26 (range 2-107) versus 5.6 (0-108) mg/L; P<0.001). Histological chorioamnionitis was associated with higher umbilical cord hsCRP (75(th) percentile 2.91 mg/L (range 0-63.9) versus 75(th) percentile 0 mg/L (0-45.6); P<0.001) and procalcitonin (median 0.293 (range 0.05-27.37) versus median 0.064 (range 0.01-5.24) ug/L; P<0.001), with a sustained increase in neonatal absolute neutrophil count (median 4.5 (0.1-26.4)x10(9)/L versus 3.0 (0.1-17.8)x10(9)/L), and CRP up to 48 hours post-partum (median 10 versus 6.5 mg/L) (P<0.05 for each). CONCLUSION: Histological chorioamnionitis is associated with modest systemic inflammation in maternal and cord blood. These systemic changes may increase postnatally, potentially undermining their utility in the diagnosis of early-onset neonatal infection

Quantitative Microscopy Reveals Centromeric Chromatin Stability, Size, and Cell Cycle Mechanisms to Maintain Centromere Homeostasis

The deposited item is a book chapter and is part of the series "Centromeres and Kinetochores" published by the publisher Springer Verlag. The deposited book chapter is a post-print version and has been submitted to peer reviewing. There is no public supplementary material available for this publication. This publication hasn't any creative commons license associated.Centromeres are chromatin domains specified by nucleosomes containing the histone H3 variant, CENP-A. This unique centromeric structure is at the heart of a strong self-templating epigenetic mechanism that renders centromeres heritable. We review how specific quantitative microscopy approaches have contributed to the determination of the copy number, architecture, size, and dynamics of centromeric chromatin and its associated centromere complex and kinetochore. These efforts revealed that the key to long-term centromere maintenance is the slow turnover of CENP-A nucleosomes, a critical size of the chromatin domain and its cell cycle-coupled replication. These features come together to maintain homeostasis of a chromatin locus that directs its own epigenetic inheritance and facilitates the assembly of the mitotic kinetochore.There are no funders and sponsors indicated explicitly in the document.info:eu-repo/semantics/publishedVersio