Protective efficiacy of taurine against pulmonary edema progression: experimental study

Re-expansion pulmonary edema (RPE) is an acute, rare and potentially lethal complication [1,2]. Its beginning is sudden and dramatic. The mechanism is not yet fully understood [1]. Some authors suggest that it may occur after rapid re-inflation of a collapsed lung [1]. It was reported by other authors that it may relate to surfactant depletion or may result from hypoxic capillary damage, leading to increased capillary permeability [1,3]. In RPE, unilateral lung injury is initiated by cytotoxic oxygen metabolites and temporally associated with an influx of polymorphonuclear neutrophils [1]. These toxic oxygen products are the results of re-oxygenation of a collapsed lung. Treatment of re-expansion pulmonary edema is basically preventive [4]

Protective efficiacy of taurine against pulmonary edema progression: experimental study

Re-expansion pulmonary edema (RPE) is an acute, rare and potentially lethal complication [1,2]. Its beginning is sudden and dramatic. The mechanism is not yet fully understood [1]. Some authors suggest that it may occur after rapid re-inflation of a collapsed lung [1]. It was reported by other authors that it may relate to surfactant depletion or may result from hypoxic capillary damage, leading to increased capillary permeability [1,3]. In RPE, unilateral lung injury is initiated by cytotoxic oxygen metabolites and temporally associated with an influx of polymorphonuclear neutrophils [1]. These toxic oxygen products are the results of re-oxygenation of a collapsed lung. Treatment of re-expansion pulmonary edema is basically preventive [4]

Accidents of the elderly living in Kocaeli Region (Turkey)

The accidents seen in the elderly have a remarkable impact on their family life and the society they live in. In this study, we have aimed to assess the prevalence, types and characteristics of the accidents seen among the elderly. We performed a cross-sectional study. The data was collected from 486 old people living in Kocaeli Region, in 2003. Demographic features, numbers and the variety of accidents were recorded after interviews. The data were also obtained from a questionnaire given after a physical examination. The ratio of accidents was found to be 9.5% (46 cases) in the study group; of those 71.7% were indoor and 28.3% outdoor accidents. The causes of the accidents were falls (69.6%), cuts (13.0%) and stings (10.9%). The distribution of the indoor accidents was 72.7% for falls, 12.1% for cuts, 9.1% for stings and 6.1% for other injuries. The distribution of the outdoor accidents was 61.5% for falls, 15.4% for cuts, 15.4% for stings and 7.7% for burns. Fall-induced injuries seem to be a major problem among the elderly. The results of our study indicate that the occurrence of indoor accidents is an important health problem in the geriatric population. Crown Copyright (C) 2008 Published by Elsevier Ireland Ltd. All rights reserved

The volume prediction on the experimental design hippocampus using stereological method.

The application of stereologic techniques to the analysis of the nervous system has greatly contributed to the evaluation of the normal and pathological anatomy of the aging brain. Currently, the hippocampus still holds secrets about the aging process. Experimental researches on hippocampus morphology may contribute to the future researches. This study presents the volume and weight of left hippocampus using a stereological technique on light microscope. The mean weight of the encephalon without cerebellum was 6.1 +/- 0.1 g. The mean weight and the volume of the hippocampus were (mean perpendicular to SD) 0.28 perpendicular to 0.02 g and 0.28 perpendicular to 0.02 cm(3), respectively. The mean coefficient of error for the stereological volume estimation of the hippocampus was 0.03. The individual volume estimation of the subjects may be achieved by the Cavalieri method. Investigators believed that the findings and the applied technique in this study may be useful for clinicians

The role of allopurinol in experimental acute necrotizing pancreatitis

Background & objectives: Acute pancreatitis (AP) in its severe form can lead to severe complications and death. Translocation of bacteria from the gut is one of the most important factors in the development of septic complications and mortality in acute pancreatitis. Oxygen-derived free radicals have been suggested to play a major role in the pathogenesis of AP. Xanthine oxidase enzyme is an important source of reactive oxygen metabolites. We undertook this study to evaluate the effect of allopurinol on bacterial translocation, oxidative stress and the course of AP in a rat model