359 research outputs found

    On the trophic fate of Phaeocystis pouchetii: VII. Sterols and fatty acids reveal sedimentation of Phaocystis-derived organic matter via krill fecal strings

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    As part of a joint project on the fate of phytoplankton in Balsfjorden in Northern Norway, we investigated the trophic fate and sedimentation potential of Phaeocystis pouchetii by tracing the transition of biomarker patterns from a phytoplankton bloom to sediment traps and during a gut passage experiment. The phytoplankton biomass during the spring bloom 1996 was dominated by colonial P. pouchetii (ca. 85 %) and four members of the diatom family Thalassiosiraceae (ca. 10%). Particulate organic carbon in sediment traps largely consisted of fecal material from the Arctic krill Thysanoessa sp.. Sterol and fatty acid biomarker patterns in the phytoplankton bloom could be reproduced by combining the individual biomarker patterns of the isolated phytoplankters P. pouchetii and Thalassiosira decipiens in a ratio of ca. 75:25. In a laboratory experiment, Arctic krill (Thysanoessa raschii) fed with similar efficiency on Phaeocystis colonies and the Thalassiosiraceae. During gut passage, the abundance of Thalassiosiraceae biomarkers in fecal strings increased relative to Phaeocystis biomarkers, while biomarkers from krill became dominant. This transition of biomarker patterns due to gut passage in T. raschii closely resembled the biomarker transition from the surface bloom to material in sediment traps at 40-170 m depth, which was mainly composed of krill fecal strings. We conclude that krill grazed efficiently on Phaeocystis colonies in Balsfjorden, and caused sedimentation of Phaeocystis-derived organic matter below the euphotic zone via fecal strings. Hence, both transfer to higher trophic levels and sedimentation of Phaeocystis-derived organic matter can be more effective than commonly believed

    The Critics of Wuthering Heights

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    The study will deal with the history of criticism of the novel from 1847 to the present time with special emphasis on the contemporary attitudes which explain the unreasoned damnation under which it was smothered for so many years

    De novo mutations in SMCHD1 cause Bosma arhinia microphthalmia syndrome and abrogate nasal development

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    Bosma arhinia microphthalmia syndrome (BAMS) is an extremely rare and striking condition characterized by complete absence of the nose with or without ocular defects. We report here that missense mutations in the epigenetic regulator SMCHD1 mapping to the extended ATPase domain of the encoded protein cause BAMS in all 14 cases studied. All mutations were de novo where parental DNA was available. Biochemical tests and in vivo assays in Xenopus laevis embryos suggest that these mutations may behave as gain-of-function alleles. This finding is in contrast to the loss-of-function mutations in SMCHD1 that have been associated with facioscapulohumeral muscular dystrophy (FSHD) type 2. Our results establish SMCHD1 as a key player in nasal development and provide biochemical insight into its enzymatic function that may be exploited for development of therapeutics for FSHD

    Adopsjon til Guds barn "Hvordan er det å bli adoptert til Guds barn en kontrast til å være under loven, ifølge Galaterne 4,1-7?"

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    Denne avhandlingen svarer på følgende forskningsspørsmål: «Hvordan er det å bli adoptert til Guds barn en kontrast til å være under loven, ifølge Galaterne 4,1-7?» Dette blir gjort gjennom historisk eksegetiske metoder. Først blir den jødiske bakgrunnen for Paulus’ bruk av adopsjonsbegrepet υἱοθεσία undersøkt. Deretter blir den romerske rettspraksisen for adopsjon undersøkt, før bakgrunnen for uttrykket αββα i Gal 4,6 blir undersøkt. Eksegesen av Gal 4,1-7 viser at Paulus sammenligner det å være under loven med å være en umyndig arving som ikke på noen måte er forskjellig fra en slave (vers 1-2). Det å være under loven innebærer at en er slave under verdens grunnelementer (vers 3). Disse grunnelementene kan forstås som verdens elementære og styrende prinsipper. Vi var slaver under verdens styrende prinsipper inntil Gud sendte sin Sønn for å frigjøre oss fra loven og adoptere oss til sine sønner. Det å bli adoptert til sønner er slik en motsetning til slavekåret under loven og verdens grunnelementer. Undersøkelsen av den romerske rettspraksisen viser at den adopterte får alle rettigheter som hører med å tilhøre den nye familien. Gal 4,1-7 uttrykker følgelig en statusendring fra slave til sønn med alle tilhørende rettigheter. Paulus’ argument om adopsjon kulminerer i påstanden om at den troende er blitt arving (vers 7). Denne arveretten får en ikke gjennom den mosaiske loven (Gal 3,18), men kun gjennom guddommelig adopsjon. Den troende er ikke lenger under den mosaiske lovens autoritet men under Faderens autoritet. Forestillingen om gudommelig adopsjon alluderer til adopsjonsløftet i 2 Sam 7,14 og tradisjonen etter dette løftet. Den tidligjødiske tradisjonen anvendte løftet om guddommelig adopsjon anvendt både på Messias og på Israel, og den knytter adopsjonsløftet til den nye pakt. I lys av tradisjonen etter 2 Sam 7,14, sammen med Gal 3,26-27, kan en tolke adopsjonen i Gal 4,5 til å innebære at den troende deltar i løftet om guddommelig adopsjon og får del i Jesu sønnekår. Videre roper Den Hellige Ånd «αββα» fra den troendes hjerte (Gal 4,6). Dette er det samme begrepet Jesus brukte for å tiltale sin far (Mark 14,36). Sett i forhold til å være under loven, innebærer det å bli adoptert til Guds sønner følgelig en statusendring, et skifte i autoritet og et nytt paktforhold til Gud.publishedVersio

    Women in Public Relations (1982-2019)

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    Purpose This paper aims to analyse the current literature on women in public relations to establish trends and areas of inquiry in the literature and identify research gaps for future research. Design/methodology/approach A total of 223 articles have been empirically analysed using thematic analysis to identify trends in the existing literature. The data has been coded and analysed per decade (1982–1989, 1990–1999, 2000–2009, 2010–2019). The articles have been identified by searching major journals in the field of public relations and communications, as well as snowballing from identified articles. Findings The results show that the majority of academic articles have been produced by using lived experiences of women working in the public relations industry and thus reflect the professional situation of female public relations employees. The results show that the position of women has reached a full circle in four decades of research and returned to the discriminatory work environment. Finally, the results show that a liberal feminist perspective has an advantage in the literature since the majority of works have been produced in the United States; however, there is an increase in authors calling for the use of socialist and radical feminism. Originality/value The paper provides a comprehensive literature review of works published in the field. The paper takes an empirical approach to the analysis rather than the descriptive one, which helped in identifying major trends in the research and identified a research gap for future inquiries

    The endocannabinoid system links gut microbiota to adipogenesis

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    We investigated several models of gut microbiota modulation: selective (prebiotics, probiotics, high-fat), drastic (antibiotics, germ-free mice) and mice bearing specific mutations of a key gene involved in the toll-like receptors (TLR) bacteria-host interaction (Myd88−/−). Here we report that gut microbiota modulates the intestinal endocannabinoid (eCB) system-tone, which in turn regulates gut permeability and plasma lipopolysaccharide (LPS) levels.The activation of the intestinal endocannabinoid system increases gut permeability which in turn enhances plasma LPS levels and inflammation in physiological and pathological conditions such as obesity and type 2 diabetes.The investigation of adipocyte differentiation and lipogenesis (both markers of adipogenesis) indicate that gut microbiota controls adipose tissue physiology through LPS-eCB system regulatory loops and may play a critical role in the adipose tissue plasticity during obesity.In vivo, ex vivo and in vitro studies indicate that LPS acts as a master switch on adipose tissue metabolism, by blocking the cannabinoid-driven adipogenesis

    Sea-ice dynamics in an Arctic coastal polynya during the past 6500 years

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    The production of high-salinity brines during sea-ice freezing in circum-arctic coastal polynyas is thought to be part of northern deep water formation as it supplies additional dense waters to the Atlantic meridional overturning circulation system. To better predict the effect of possible future summer ice-free conditions in the Arctic Ocean on global climate, it is important to improve our understanding of how climate change has affected sea-ice and brine formation, and thus finally dense water formation during the past. Here, we show temporal coherence between sea-ice conditions in a key Arctic polynya (Storfjorden, Svalbard) and patterns of deep water convection in the neighbouring Nordic Seas over the last 6500 years. A period of frequent sea-ice melting and freezing between 6.5 and 2.8 ka BP coincided with enhanced deep water renewal in the Nordic Seas. Near-permanent sea-ice cover and low brine rejection after 2.8 ka BP likely reduced the overflow of high-salinity shelf waters, concomitant with a gradual slow down of deep water convection in the Nordic Seas, which occurred along with a regional expansion in sea-ice and surface water freshening. The Storfjorden polynya sea-ice factory restarted at ~0.5 ka BP, coincident with renewed deep water penetration to the Arctic and climate amelioration over Svalbard. The identified synergy between Arctic polynya sea-ice conditions and deep water convection during the present interglacial is an indication of the potential consequences for ocean ventilation during states with permanent sea-ice cover or future Arctic ice-free conditions

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