Understanding Work Group Culture on Rehabilitation Units: The Key to Facilitating Group Innovation and Promoting Integration

Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/93523/1/j.2048-7940.1996.tb01666.x.pd

Mechanisms of growth inhibition of primary prostate epithelial cells following gamma irradiation or photodynamic therapy including senscence, necrosis, and autophagy, but not apoptosis

In comparison to more differentiated cells, prostate cancer stem-like cells are radioresistant, which could explain radio-recurrent prostate cancer. Improvement of radiotherapeutic efficacy may therefore require combination therapy. We have investigated the consequences of treating primary prostate epithelial cells with gamma irradiation and photodynamic therapy (PDT), both of which act through production of reactive oxygen species (ROS). Primary prostate epithelial cells were cultured from patient samples of benign prostatic hyperplasia and prostate cancer prior to treatment with PDT or gamma irradiation. Cell viability was measured using MTT and alamar blue assay, and cell recovery by colony-forming assays. Immunofluorescence of gamma-H2AX foci was used to quantify DNA damage, and autophagy and apoptosis were assessed using Western blots. Necrosis and senescence were measured by propidium iodide staining and beta-galactosidase staining, respectively. Both PDT and gamma irradiation reduced the colony-forming ability of primary prostate epithelial cells. PDT reduced the viability of all types of cells in the cultures, including stem-like cells and more differentiated cells. PDT induced necrosis and autophagy, whereas gamma irradiation induced senescence, but neither treatment induced apoptosis. PDT and gamma irradiation therefore inhibit cell growth by different mechanisms. We suggest these treatments would be suitable for use in combination as sequential treatments against prostate cancer

Radical political unionism reassessed

Defections from European social-democratic parties and a resurgence of union militancy have prompted some to diagnose a new left-wing trade unionism across Europe. This comment on the article by Connolly and Darlington scrutinizes trends in France and Germany but primarily analyses recent developments in Britain. While there are some instances of disaffiliation from the Labour Party, support for electoral alternatives, growth in political militancy and emphasis on new forms of internationalism, these have been limited. There is insufficient evidence to suggest that we are witnessing the making of a new radical collectivism

The application of time-series MODIS NDVI profiles for the acquisition of crop information across Afghanistan

We investigated and developed a prototype crop information system integrating 250 m Moderate Resolution Imaging Spectroradiometer (MODIS) normalized difference vegetation index (NDVI) data with other available remotely sensed imagery, field data, and knowledge as part of a wider project monitoring opium and cereal crops. NDVI profiles exhibited large geographical variations in timing, height, shape, and number of peaks, with characteristics determined by underlying crop mixes, growth cycles, and agricultural practices. MODIS pixels were typically bigger than the field sizes, but profiles were indicators of crop phenology as the growth stages of the main first-cycle crops (opium poppy and cereals) were in phase. Profiles were used to investigate crop rotations, areas of newly exploited agriculture, localized variation in land management, and environmental factors such as water availability and disease. Near-real-time tracking of the current years’ profile provided forecasts of crop growth stages, early warning of drought, and mapping of affected areas. Derived data products and bulletins provided timely crop information to the UK Government and other international stakeholders to assist the development of counter-narcotic policy, plan activity, and measure progress. Results show the potential for transferring these techniques to other agricultural systems

Survey and monitoring of opium poppy and wheat in Afghanistan: 2003-2009

An integrated application of remote-sensing technology was devised and applied in Afghanistan during 2003–2009 providing critical information on cereal and poppy cultivation and poppy eradication. The results influenced UK and international policy and counter-narcotics actions in Afghanistan

Morphology and biomechanics of the nests of the Common Blackbird Turdus merula

Capsule Common blackbirds select different materials, with varying biomechanical properties, to construct different parts of their nest. Aims This study tested the hypothesis that outer components of a nest have a more structural role and so are stronger than materials used to line the cup. Methods Blackbird nests were measured prior to being dismantled to isolate structural components which were tested for mechanical strength and rigidity. Results Outer nest wall materials were significantly thicker, stronger and more rigid than materials in the inner structural wall or the cup lining. In the vertical plane materials used in the structural wall did not differ. By contrast, lining materials from the bottom of the nest cup were significantly thicker, stronger and more rigid than materials from the top of the cup. Conclusion Blackbirds use different materials in nest construction roles suited to their properties and so may be able to recognise the structural properties of these materials. Materials on the outside of the nest may have a key structural role during construction

Banks-Zaks fixed point analysis in momentum subtraction schemes

We analyse the critical exponents relating to the quark mass anomalous dimension and beta-function at the Banks-Zaks fixed point in Quantum Chromodynamics (QCD) in a variety of representations for the quark in the momentum subtraction (MOM) schemes of Celmaster and Gonsalves. For a specific range of values of the number of quark flavours, estimates of the exponents appear to be scheme independent. Using the recent five loop modified minimal subtraction (MSbar) scheme quark mass anomalous dimension and estimates of the fixed point location we estimate the associated exponent as 0.263-0.268 for the SU(3) colour group and 12 flavours when the quarks are in the fundamental representation.Comment: 33 latex pages, 25 tables, anc directory contains txt file with electronic version of renormalization group function